Novartis Continues to Outpace The Market, Delivering Strong First Quarter 2005 Sales and Earnings Growth


BASEL, Switzerland, April 21, 2005 (PRIMEZONE) -- Novartis (NYSE:NVS): Key figures


 First quarter
                              Q1 2005           Q1 2004      % Change 
                                 % of              % of 
                     USD m  net sales  USD m  net sales       USD  lc 

 Net sales           7,341             6,639                   11   7 
  Pharmaceuticals    4,789             4,310                   11   8 
  Sandoz               803               719                   12   7 
  Consumer Health    1,749             1,610                    9   6 
 Operating income    1,680       22.9  1,454(a)    21.9        16 
 Net income          1,477       20.1  1,270(a)    19.1        16 
 Basic earnings 
  per share/ADS        USD               USD    
                      0.63            0.54(a)                  17
 (a) Pro forma basis

 -- Group net sales rise 11% (+7% lc) based on strong sales growth 
    in Pharmaceuticals and Sandoz generics
 -- Pharmaceuticals, led by oncology and cardiovascular portfolios, 
    delivers sales growth of 11% (+8% lc) in a challenging 
    environment 
 -- Sandoz performs well as sales rise 12% (+7% lc), thanks to 
    strong European performance; Hexal and Eon Labs integration 
    plans on track
 -- Consumer Health sales up 9% (+6% lc) as focus on key brands and 
    new product launches underpin sales expansion
 -- Operating income climbs 16%
 -- Net income rises 16% and earnings per share increases 17% to USD 
    0.63

(a) This quarterly report incorporates for the first time the adoption of new IFRS accounting standards that became effective on January 1, 2005, and other presentational changes. In order to provide a comparable basis, the 2004 pro forma statements reflect these changes as if they had been in effect already during 2004.

Commenting on the first-quarter results published today, Dr. Daniel Vasella, Chairman and CEO of Novartis, said, "We are off to a strong start in 2005. In Pharmaceuticals, we once more gained market share, especially through the dynamic performance of our oncology portfolio. Our plans to integrate Hexal and Eon Labs, making Sandoz the world leader in generics are on track, and will further strengthen our ability to fulfill customer needs with a broad health-care portfolio in the context of an aging population and rising health-care needs. We anticipate delivering a competitive performance in 2005 with record sales and, on a comparable basis, record earnings."

Net sales

Group net sales up 11% to USD 7.3 billion

Double-digit sales growth of 11% (+7% in local currencies, or lc) to USD 7.3 billion was driven by Pharmaceuticals, which once again gained market share, and Sandoz, which posted a solid performance. Volume increases accounted for seven percentage points of Group net sales growth. Currency benefits contributed four percentage points, while acquisitions added one percentage point. Net price decreases led to a decline of one percentage point. Pharmaceuticals provided 65% of total Group net sales, Sandoz 11% and Consumer Health 24%. Geographically, the U.S. accounted for 38% of total Group net sales, Europe 39% and other regions for 23%.

Novartis increased its share of the global health-care market to 4.5% for the first two months of 2005, up from 4.4% in the same year-ago period, according to IMS Health.

Pharmaceuticals net sales rise 11% to USD 4.8 billion

The Pharmaceuticals Division, led by the performance of the key brands Diovan, Gleevec/Glivec, Femara, Lamisil and Zometa, reported a net sales increase of 11% (+8% lc). This is after deducting a one-time adjustment of USD 62 million to reflect the change in accounting for sales rebates in prior years in the U.S. on inventory held by wholesalers and retailers. Excluding this one-time adjustment, net sales would have risen 13% (+10% lc).

Both Primary Care and Specialty Medicines, in particular the oncology and cardiovascular portfolios, contributed to the strong Pharmaceuticals performance. Sales growth was driven by volume expansion, contributing eight percentage points, while currency benefits added three percentage points. Primary Care (excluding Mature Products) reported a net sales increase of 13% (+10% lc). The Cardiovascular franchise improved 12% (+9% lc) despite increased competition. Net sales in Specialty Medicines, which includes activities in Oncology, Transplantation & Immunology, and Ophthalmics, rose 20% (+16% lc). Oncology delivered dynamic growth of 26% (+22% lc) based on leading performances of the "best-in-class" oncology drugs Gleevec/Glivec, Zometa and Femara.

First-quarter net sales in the U.S. rose 5% to USD 1.8 billion after deducting the change in accounting, but were up 9% excluding the impact. In Europe, net sales rose 15% (+9% lc), while net sales advanced 19% (+16% lc) in Japan and 12% (+9% lc) in Latin America. Sales in the emerging growth markets climbed 17% (+11% lc).

Sandoz sales up 12% to USD 803 million

First-quarter sales were up 12% (+7% lc) to USD 803 million, helped by strong growth in Europe and the benefits of the Durascan and Sabex acquisitions made in 2004. The U.S. generics business remained very competitive, but Anti-infectives delivered solid growth, benefiting from substantial volume increases. Overall, volumes contributed eight percentage points to growth. Currencies and acquisitions each contributed five percentage points, with continued pricing pressure resulting in a decline of six percentage points.

Consumer Health net sales up 9% to USD 1.7 billion

Net sales rose 9% (+6% lc) to USD 1.7 billion thanks to strong double-digit sales growth in Medical Nutrition and Animal Health as well as solid performances in CIBA Vision, OTC and Infant & Baby. Medical Nutrition continued to benefit from the Mead Johnson acquisition, while growth in Animal Health was driven by the continued strong performance of new products in the U.S. and major European markets. CIBA Vision growth came from the U.S. launch of O2OPTIX breathable contact lenses and continued success of Focus DAILIES lenses. OTC sales were supported by a strong cough/cold brands performance, which was partially offset by a shrinking smoking-cessation market in Europe. Infant & Baby continued to perform well in the U.S. based on an innovative product strategy. Overall, increased volumes accounted for five percentage points of sales growth, currencies for three percentage points and acquisitions for one percentage point. There was no significant impact from price changes.


 Operating income

 First quarter

                              Q1 2005         Q1 2004(a)    Change   
                                 % of              % of 
                     USD m  net sales  USD m  net sales       in %


 Pharmaceuticals     1,364       28.5  1,251       29.0          9 
 Sandoz                110       13.7     91       12.7         21
 Consumer Health       286       16.4    265       16.5          8
 Corporate income &
  expense, net         -80              -153 
 Total               1,680       22.9  1,454       21.9         16 

 (a) Pro forma basis

Group operating income up 16% to USD 1.7 billion

Operating income advanced faster than sales, driven by the strong business performance across all three divisions, leading to a one percentage point improvement in the operating margin. A divestment gain of USD 135 million for the anti-hypertension product Cibacen in Europe also boosted the performance. Excluding the change in accounting for sales rebates in prior years in the U.S. and gain from the Cibacen divestment, operating income would have grown 11%, in line with sales.

Pharmaceuticals operating income climbs 9% to USD 1.4 billion

Operating income expanded 9% to USD 1.4 billion in the first quarter. Cost of Goods Sold (COGS) increased 0.7 percentage points to 17.1% of sales, which was mainly affected by the weaker U.S. dollar. Marketing & Sales expenses rose 14%, in particular for pre-launch and launch investments in products such as Enablex (incontinence), Femara (extended adjuvant breast cancer) and Aclasta (Paget's disease), which were partially offset by productivity gains. Research & Development expenses advanced faster than sales, rising 16% and accounting for 18.9% of sales following the ramp-up of late-stage clinical trials, in particular for LAF237 (diabetes) and SPP100 (hypertension) as well as investments in the Novartis Institute for BioMedical Research (NIBR) and one-time provisions for closing a research site in London. Other Income & Expense decreased 45%, mainly as a result of the divestments gains related to Cibacen. General & Administrative expenses rose slower than sales and accounted for 3.2% of sales.

Sandoz operating income rises 21% to USD 110 million

Operating income rose significantly, advancing 21% to USD 110 million. The strong business expansion was a key factor, which was supported by a decline in Marketing & Sales expenses as a percentage of sales due to cost containment measures. In addition, other Income & Expense in the first quarter benefited from one-time gains on the disposal of distributorship businesses in Eastern Europe, while General & Administrative expenses were negatively affected by costs associated with litigation. These developments more than offset an increase in Cost of Goods Sold (COGS) as a result of product mix changes, ongoing pricing pressure in certain markets and higher R&D spending in support of major initiatives, in particular in biopharmaceuticals.

Consumer Health operating income advances 8% to USD 286 million

Operating income increased 8%, in line with sales. Cost of Goods Sold, Research & Development and General & Administrative expenses were close to year-ago levels as a percentage of sales, while Marketing & Sales rose following new product launches, in particular the O2OPTIX launch by CIBA Vision.

Group net income rises 16% to USD 1.5 billion

Net income rose 16% to USD 1.5 billion in the first quarter from USD 1.3 billion (pro forma) in the year-ago period based on the strong business performance. As a percentage of net sales, net income rose to 20.1% from 19.1 % in the 2004 first quarter.

Group outlook (barring any unforeseen events)

Novartis reaffirms its 2005 outlook. Further gains in market share are expected to keep Novartis positioned as one of the fastest-growing pharmaceutical companies, delivering high single-digit net sales growth for the Group and Pharmaceuticals in local currencies.

Barring any unforeseen events, Group operating and net income should reach new record levels on a comparable basis.

Pharmaceutical business and key product highlights

(Note: All net sales percentage figures refer to first-quarter 2005 results)

Primary Care

Diovan (+17%; +14% lc; +10% U.S.), the No. 1 angiotensin-receptor blocker (ARB) worldwide, maintained its share of this market segment in the U.S. at 38%. Diovan remained one of the fastest-growing branded anti-hypertension medicines despite increased competition (IMS Health data as of March 2005). More than 200,000 patients have been enrolled in a Novartis-sponsored U.S. hypertension awareness and education program since its inception, helping to support ongoing growth. Novartis remains in discussion with the U.S. Food and Drug Administration (FDA) regarding an approvable letter granted in early 2005 for Diovan to treat and protect patients after suffering a heart attack, an indication already approved in 37 countries, including the U.K., Sweden and Switzerland. European sales growth was strong with key performances in France, Italy and Germany, in particular from the Co-Diovan formulation.

In March 2005, Novartis received a letter from a generic company with notification of its Abbreviated New Drug Application (ANDA) to the FDA seeking to market a generic version of valsartan, the active ingredient in Diovan. In its ANDA, a so-called "505(j) application," the company submitted a Paragraph IV certification that its generic version did not infringe the claims of a patent expiring in 2017 covering the formulation of Diovan. However, the ANDA included no challenge (a so-called Paragraph III certification) against a compound patent expiring in 2012 covering the valsartan active ingredient. As a result, the generic company cannot market a product until at least 2012. Novartis has decided not to initiate patent litigation at this time against the generic company on its application. Novartis will continue to vigorously defend its intellectual property related to Diovan.

Lotrel (+4% U.S.), the No. 1 U.S. fixed combination treatment for hypertension, increased its market share in the first quarter, helped by data showing that more than 60% of patients in the U.S. require two or more drugs to bring hypertension under control. Sales growth, however, was negatively affected by inventory de-stocking. Lotrel continues to be ranked as the No. 1 branded combination therapy, a position held since 2002. This product also benefited from the disease and education awareness initiatives in the U.S.

Lamisil (+13%; +11% lc; +9% U.S.), the leading treatment worldwide for fungal nail infections, delivered a strong performance, driven by greater disease awareness in the U.S. and robust-double digit growth in Europe, particularly in U.K., France, Belgium and Holland.

Elidel (+34%; +32% lc; +30% U.S.), a leading medicine for eczema, reported higher sales in the first quarter. Novartis is currently in product labeling discussions with the FDA after an FDA Advisory Committee in February recommended the inclusion of a "black box" warning for Elidel and Protopic(r) to warn the public of a theoretical risk of cancer. Novartis and independent experts do not agree that these actions are justified. Further, Novartis remains confident in the safety and efficacy of Elidel in its approved indications.

Zelnorm/Zelmac (+18%; +16% lc +17% U.S.), a breakthrough therapy for irritable bowel syndrome (IBS) with constipation (IBS-C) and the first and only prescription medicine for chronic idiopathic constipation, delivered solid double-digit sales growth. Zelnorm has reached a 60% share of the IBS market in the U.S., where it is also the only branded treatment for chronic constipation, a condition that affects more than 20 million people. Novartis is launching a series of initiatives in 2005 to grow awareness about the benefits of Zelnorm for treating chronic constipation.

Specialty Medicines

Oncology

Gleevec/Glivec (+41%; +36% lc; +55% U.S.), for all stages of Philadelphia-chromosome positive (Ph+) chronic myeloid leukemia (CML) and certain forms of gastro-intestinal stromal tumors (GIST), maintained a strong double-digit growth rate amid solid performances in the U.S. as well as in key European markets. Growth drivers included further penetration of both the CML and GIST markets, in part through improved diagnosis and educational programs, and an increase in the average daily dose. More than 100 clinical trials are underway with Gleevec/Glivec, including Phase II trials in combination with hydroxyurea in glioblastoma multiforme (GBM), a type of brain tumor, and a Phase III NCI-sponsored study in the adjuvant GIST setting. The FDA has granted an expanded label in the U.S. for CML that includes longer-term and molecular response data. The Glivec International Patient Assistance Program is now open in 74 countries, and the combined Gleevec/Glivec patient assistance programs are providing treatments to 10,800 patients worldwide who otherwise would not have access to this innovative therapy.

Zometa (+17%; +15% lc; +13% U.S.), the leading intravenous bisphosphonate worldwide for bone metastases, delivered double-digit growth after achieving blockbuster status in 2004. Growth in 2005 is expected to moderate slightly given high penetration rates in breast cancer and myeloma as well as the continuing impact of U.S. reimbursement reforms and increasing competition. At the same time, Zometa continues to make progress in increasing the use of intravenous (IV) bisphosphonates in the treatment of prostate and lung cancer patients, two of the most common forms of cancer.

Femara (+51%; +47% lc; +85% U.S.) continued to grow at high double-digit rates in the first quarter, supported by robust clinical data supporting its position as a leading therapy for early and advanced breast cancer in postmenopausal women. Initial data from the BIG 1-98 study, presented in January, showed Femara provided a disease-free survival advantage over tamoxifen in the adjuvant treatment (post-surgery) of early breast cancer. The BIG 1-98 data will be featured at the upcoming American Society of Clinical Oncology meeting in May and forms the basis for U.S. and EU submissions planned for the second quarter of 2005 for this indication. Femara was approved in the first quarter in Germany, France and seven other countries as the only hormone therapy given after standard tamoxifen treatment for postmenopausal women with early breast cancer, an indication now approved in more than 75 countries, including the U.S. This approval was based on the landmark MA-17 study, which showed Femara significantly increases a woman's chance of staying cancer-free following five years of adjuvant tamoxifen therapy.

Sandostatin (+11%; +7% lc; +7% U.S.), a leading treatment for patients with the hormone condition acromegaly and also for symptoms of gastro-entero-pancreatic neuroendocrine tumors, maintained recent growth rates thanks to a double-digit expansion for the patient-friendly, long-acting LAR version, which accounted for approximately 70% of global sales. A generic competitor received US approval in March to market a subcutaneous version of Sandostatin. The LAR formulation provides significant advantages for patients in terms of comfort and convenience since it is administered once-monthly compared to an average 90 injections per month for the generic formulation.

Ophthalmics

The ongoing strong performance from Visudyne (+23%; +19% lc; +13% U.S.) in the U.S. and Europe supported net sales growth of 23% (+19% lc) for the business unit despite the launch in early 2005 of a competing product in the U.S. for the treatment of "wet" AMD (age-related macular degeneration), a leading cause of blindness.

Transplantation

Sales for the business unit declined 6% (-9% lc) as the Neoral/Sandimmun franchise (-10%; -13% lc; -18% U.S.) was primarily affected by erosion from generic competition in the U.S. and other markets. Myfortic, an immunosuppressant used in kidney transplantation, continued to gain market share globally, with regional launches occurring during the first quarter in France, Canada and Spain. Certican, a proliferation signal inhibitor designed to reduce the risk for chronic allograft failure, was launched in Spain in the first quarter and received positive recommendations for approval in Australia, South Africa and Israel, continuing the momentum of world-wide approvals.

Product and regulatory update

Novartis has an attractive pipeline, which includes several projects that have the potential to become a new standard of care and the first to market in their respective classes. A number of projects are currently awaiting regulatory approval or planned to be submitted in 2005:


 -- Exjade (deferasirox), a once-daily oral iron chelator, is 
    expected to be submitted for U.S. and EU approval with Orphan 
    Drug Status in the second quarter of 2005. Formerly known as 
    ICL670, Exjade is used to treat iron overload, a cumulative, 
    potentially life-threatening condition associated with blood 
    transfusions.

 -- The FDA issued an "approvable" letter for Aclasta (zoledronic 
    acid 5 mg solution for infusion) for the treatment of Paget's 
    disease of the bone in March 2005. Novartis will be working 
    closely with the FDA with regard to the information needed to 
    obtain final approval. Aclasta is also being developed as a 
    once-yearly treatment for osteoporosis and other metabolic 
    bone disorders.

 -- Xolair is under review by European regulatory authorities. This 
    novel agent, already approved in the U.S., offers a 
    breakthrough in treating asthma, particularly as a unique 
    add-on therapy for adults and adolescents with severe 
    persistent asthma who remain inadequately controlled with 
    conventional medicines. Xolair is being developed in 
    collaboration with Genentech and Tanox.

New clinical data from a number of development compounds are planned to be presented during the second quarter, including the following:


 -- Six-month data for FTY720 in the treatment of multiple 
    sclerosis will be presented for the first time at the European 
    Neurological Society Congress in Vienna on June 21. Data 
    from the Phase II study showed a significant reduction in the 
    relapse rate and in the number of brain lesions detected by MRI 
    scan as well as a longer time to first relapse. The vast 
    majority of patients are continuing in the extension phase. 
    Novartis intends to start the Phase III clinical study program 
    for MS in mid-2005. The ongoing Phase III study program of 
    FTY720 for the prevention of acute rejection in kidney 
    transplantation is proceeding as planned.

 -- PTK/ZK (vatalanib) data from the CONFIRM1 trial in metastatic 
    colorectal cancer has been accepted as a late-breaking 
    abstract at the American Society of Clinical Oncology meeting 
    in May. In March, Novartis and Schering AG announced positive 
    drug effects in metastatic colorectal cancer based on initial 
    Phase III results from the CONFIRM1 trial. A pre-planned 
    analysis of progression-free survival as assessed by 
    investigators achieved statistical significance, while the 
    analysis of the primary endpoint as assessed by central 
    radiology review did not achieve statistical significance. 
    The independent data monitoring board recommended that the 
    CONFIRM1 trial continue to allow analysis of overall survival, 
    with data expected in the second half of 2006. An interim 
    analysis from another Phase III trial, CONFIRM2, is planned 
    for the second half of 2005, with final overall survival data 
    expected in mid-2006. As announced in March, PTK/ZK is now 
    planned to be submitted for regulatory approval in 2007.

 -- The 12-month data for Lucentis(tm) (ranibizumab) from the 
    Phase III MARINA study in patients with minimally classic or 
    occult AMD (age-related macular degeneration is expected in 
    the second quarter of 2005. Novartis and partner Genentech 
    anticipate 12-month results from another Phase III study 
    (ANCHOR) in patients with predominantly classic AMD in the 
    fourth quarter of 2005.

 -- Phase III data for LAF237 (vildagliptin) as a monotherapy and 
    in combination with other anti-diabetic agents is expected at 
    the end of 2005, while additional data on SPP100 (aliskiren) 
    in the treatment of hypertension is expected to be available 
    in the third quarter of 2005.

Novartis has more than 70 projects in clinical development, of which more than 40 are new molecular entities. Internal discovery efforts are complemented with in-licensing activities, which included two new agreements signed so far in 2005:


 -- AD 237 is an inhaled long-acting antimuscarinic agent currently 
    in Phase II for the treatment of chronic obstructive pulmonary 
    disease (COPD) that is being developed with Vectura Group plc 
    and Arakis Ltd. Novartis will be responsible for developing AD 
    237 both as a monotherapy and in combination with QAB149, its 
    once-daily, long-acting beta2 agonist currently in Phase II 
    development. Studies have demonstrated that it is well-
    tolerated, and effective over 24 hours after a single dose. 
    The Novartis late-stage pipeline now contains two promising 
    bronchodilator drugs for the treatment of COPD, the world's 
    fourth largest cause of death and a condition caused primarily 
    by smoking.

 -- Rebamipide has recently been in-licensed from Otsuka 
    Pharmaceutical Company, Ltd. as a treatment for dry eye. 
    Currently in two Phase III trials, Novartis has obtained an 
    exclusive license to sub-license rebamipide globally, excluding 
    Japan and selected Asian countries.

Hexal and Eon Labs: Integration planning on track

Integration planning is well underway to create the world leader in the generic drug industry by bringing Sandoz together with Hexal AG, the privately-held No. 2 generics company in Germany, and Eon Labs, Inc., a fast-growing U.S. generics company that has a strategic partnership with Hexal.

Novartis announced in February the strategic acquisitions of these two leading generic drug companies, which will combine Sandoz's global geographic presence and expertise in anti-infectives, Hexal's leadership in Germany and strong track record of successful product development, and Eon Labs' strong position in the U.S. for "difficult-to-make" generics. After the closing of both transactions, which is expected in the second half of 2005, Sandoz will be the global leader in generics with combined pro forma 2004 sales of USD 5.1 billion, a portfolio of over 600 active ingredients in more than 5,000 dosage forms and more than 20,000 employees.

Submissions for regulatory approval have been made in the United States and the European Union. The tender process to acquire the publicly-held shares of Eon Labs is planned to happen in coordination with the regulatory process. These transactions are expected to close before the end of 2005.

Corporate

Corporate income & expense, net

Net corporate expenses amounted to USD 80 million in the first quarter compared to an expense of USD 153 million in 2004, mainly as a result of an increase in certain legal and indirect tax accruals in the prior-year period.

Financial income, net

Net financial income amounted to USD 45 million compared with USD 28 million in the 2004 first quarter. Currency gains accounted for the significant part of the increase. Despite the low-yield environment, the overall return on net liquidity was 2.4% versus 1.8% the same period in 2004. Result from associated companies Associated companies resulted in an overall income of USD 33 million. The Group's 42% investment in Chiron Corporation contributed a loss of USD 3 million compared with income of USD 11 million in the prior-year period. The investment in Roche resulted in income of USD 35 million. This amount consists of an estimated USD 65 million as being the Novartis share of Roche's net income for the 2005 first quarter, including a positive adjustment for Roche's actual 2004 results of USD 2 million. This was offset by charges of USD 30 million related to amortization of intangible assets.

Strong balance sheet

Novartis debt continues to be rated by Standard & Poor's and Moody's as AAA and Aaa for long-term maturities and A1+ and P1 for short-term debt, respectively, making the Group one of the few non-financial companies worldwide to have attained the highest rating from these two benchmark rating agencies.

The Group's equity fell by USD 1.8 billion in the first quarter to USD 29.5 billion at March 31, 2005, as a result of the USD 2.1 billion dividend payment, a total of USD 0.5 billion in purchases of treasury shares and USD 0.7 billion of translation losses. This more than offset first quarter net income of USD 1.5 billion. The debt/equity ratio at the end of the first quarter was 0.21:1 compared to 0.22:1 as of December 31, 2004.

Novartis continued its share repurchase program in the first quarter via a second trading line on the SWX Swiss Exchange. Since the start of the fourth program in August 2004, a total of 25.2 million shares have been repurchased for USD 1.2 billion. This included 10 million shares repurchased in the first quarter for USD 0.5 billion. Shareholders approved a resolution at the Annual General Meeting on March 1, 2005, to retire 38.0 million shares bought through the repurchase programs via the second trading line until the end of 2004.

Cash flow

Cash flow from operating activities rose by USD 918 million (+88%) to USD 2.0 billion, mainly the result of a change of USD 551 million in net working capital. This was principally due to a timing difference on the payment of withholding tax on the dividend, which will be paid in the second quarter of 2005 compared to a similar payment in the 2004 first quarter.

Disclaimer

This release contains certain forward-looking statements relating to the Group's business, which can be identified by the use of forward-looking terminology such as "will", "anticipate", "outlook", "expect", "pipeline", "potential", "planned", "will be", "intends to", or similar expressions, or by express or implied discussions regarding potential future sales of new or existing products, potential new products or potential new indications for existing products, or by other discussions of strategy, plans or intentions. Such statements reflect the current views of the Group with respect to future events and are subject to certain risks, uncertainties and assumptions. There can be no guarantee that any products will reach any particular sales levels, or that any new products will be approved for sale in any market, or that any new indications will be approved for existing products in any market. In particular, management's expectations could be affected by, among other things, new clinical data; unexpected clinical trial results; unexpected regulatory actions or delays or government regulation generally; the Group's ability to obtain or maintain patent or other proprietary intellectual property protection; competition in general; government, industry, and general public pricing pressures and other risks and factors referred to in the Group's current Form 20-F on file with the U.S. Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected. Novartis is providing the information in this press release as of this date and does not undertake any obligation to update any forward-looking statements contained in this press release as a result of new information, future events or otherwise.

About Novartis

Novartis AG (NYSE:NVS) is a world leader in pharmaceuticals and consumer health. In 2004, the Group's businesses achieved sales of USD 28.2 billion and pro forma net income of USD 5.6 billion. The Group invested approximately USD 4.2 billion in R&D. Headquartered in Basel, Switzerland, Novartis Group companies employ about 81,400 people and operate in over 140 countries around the world.

For further information please consult http://www.novartis.com.


 Further Important Dates

 July 14, 2005            First half and second quarter results 
 October 18, 2005         Nine-month and third quarter results

Please find full media release in English attached.

http://hugin.info/134323/R/990214/148804.pdf

Further language versions are available through the following links:

German version is available through the following link:

http://dominoext.novartis.com/nc/ncprre01.nsf/0/cb095cab3455f6e5c1256fe9006d791c

French version is available through the following link:

http://dominoext.novartis.com/nc/ncprre01.nsf/0/f26ca698265dba7ec1256fe9006d8d77



            

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