OraSure Technologies, Inc. (OSUR) President and CEO and Mayor Bloomberg to Ring the NASDAQ Stock Market Opening Bell

Company and NYC Mayor Join with The National Association of People With AIDS and POZ Magazine in Recognition of National HIV Testing Day


MEDIA ADVISORY, June 26, 2006 (PRIMEZONE) --



 What:
 Douglas Michels, President and CEO of OraSure Technologies,
 Inc. (OSUR), will join New York City Mayor Michael Bloomberg,
 Frank J. Oldham Jr., Executive Director, the National
 Association of People with AIDS (NAPWA), and Regan Hofmann,
 member of the NAPWA Board of Directors and Editor-in-Chief
 of POZ Magazine, to preside over the opening bell in observance
 of the twelfth annual National HIV Testing Day (NHTD). This
 important observance is a campaign led by NAPWA to encourage
 at-risk individuals to receive voluntary HIV counselling and
 testing.

 OraSure Technologies is the manufacturer of the OraQuick(r)
 ADVANCE(tm) Rapid HIV-1/2 Antibody Test, the only U.S.
 FDA-approved rapid, HIV-1/2 test that can be used with oral
 fluid, whole blood and plasma and produce results in 20 minutes.

 The Centers for Disease Control and Prevention (CDC) reports
 that as many as one-third of the estimated one million HIV-
 infected people in the United States may be unaware that they
 are infected with the HIV virus. HIV counseling and testing
 enables people with HIV to take steps to protect their own health
 and that of their partners, and helps people who test negative
 get the information they need to stay uninfected.

 Where:
 NASDAQ MarketSite -- 4 Times Square -- 43rd & Broadway
 Broadcast Studio

 When:
 Tuesday, June 27, 2006 at 9:30 a.m. EDT

 Contacts:
 OraSure:
 Erika Freed; 917-359-7974
 Erika@0to5.com

 NASDAQ MarketSite:
 Stephanie Lowenthal; 646-441-5220

Feed Information:

The opening bell is available from 9:20 a.m. to 9:35 a.m. on uplink IA-5 C-band/transponder 14. The downlink frequency is 3980 horizontal; audio: 6.2/6.8. The feed can also be found on Waterfront fiber 1623. If you have any questions, please contact Stephanie Lowenthal at (646) 441-5220.

Photos:

To obtain a hi-resolution photograph of the Market Open, please go to http://www.nasdaq.com/reference/marketsite_events.stm and click on the market open of your choice.

About OraSure Technologies

OraSure Technologies develops, manufactures and markets oral fluid specimen collection devices using proprietary oral fluid technologies, diagnostic products including immunoassays and other in vitro diagnostic tests, and other medical devices. These products are sold in the United States as well as internationally to various clinical laboratories, hospitals, clinics, community-based organizations and other public health organizations, distributors, government agencies, physicians' offices, and commercial and industrial entities.

OraSure Technologies is the leading supplier of oral-fluid collection devices and assays to hospitals, the life insurance industry and public health markets for the detection of HIV. In addition, the Company supplies oral-fluid testing solutions for drugs of abuse testing. For more information on the Company, please go to http://www.orasure.com.