Orion s partner discontinues development of levosimendan (Simdax) in the US



Orion's partner discontinues development of levosimendan (Simdax) in
the US

Orion has been informed by Abbott, the license holder for the
intravenously administered formulation of levosimendan (trade name
Simdax), an Orion-originated compound for acute decompensated heart
failure, that Abbott has decided not to continue the development
program for the product in the US, because it would not be
commercially reasonable. Accordingly, the considered additional Phase
3 studies will not be conducted by Abbott.

Abbott continues to assess feedback from discussions with European
authorities.

Simdax will remain available in the markets where it already has been
approved. The product has marketing authorisations or submitted
applications in more than 40 countries.

Under a renewed licensing agreement concluded in April 2004, Abbott
took over the development programme of the intravenously administered
formulation of levosimendan and received also extended marketing
rights to the product.




Orion Corporation



Jukka Viinanen                                        Olli Huotari
President and CEO                                  Senior Vice
President, Corporate Functions




Contact person:
Jukka Viinanen, President and CEO, Orion Corporation, phone +358 10
426 3710




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