BIOTIE THERAPIES CORP. STOCK EXCHANGE ANNOUNCEMENT 30 April 2007 SUBSCRIPTION OF SHARES IN BIOTIE ON THE BASIS OF OPTION RIGHTS A total of 231,200 new shares in Biotie Therapies Corp. have been subscribed for by exercising the series A option rights of the company's option scheme determined on 30 March 2006. The subscription price of the shares was EUR 0.60 per share. The new shares have been entered in the Finnish Trade Register on 30 April 2007. Following the increase, the total number of shares in Biotie Therapies Corp. is 90,031,860. The share capital has not been increased. The subscribed shares entitle their holders to dividend as of the financial year 2007 and to other shareholder rights as of the registration. The new shares shall be subject to public trading on the official list of the Helsinki Stock Exchange together with the old shares on 2 May 2007. The subscription period for the shares pursuant to the series A option rights of the company's option scheme determined on 30 March 2006 commenced on 1 January 2007 and it will end on 31 December 2011. So far, a total of 231,200 new shares have been subscribed for pursuant to the series A option rights of the company's option scheme determined by the company on 30 March 2006. Turku, 30 April 2007 Biotie Therapies Corp. Timo Veromaa President and CEO For further information, please contact: Timo Veromaa, President and CEO, Biotie Therapies Corp. tel. +358 2 274 8901, e-mail: timo.veromaa@biotie.com www.biotie.com Distribution: Helsinki Stock Exchange Main Media