Report pursuant to the Danish Securities Trading Act, Section 28a


TopoTarget A/S
Symbion
Fruebjergvej 3
DK 2100 Copenhagen
Denmark
Tel: +45 39 17 83 92
Fax: +45 39 17 94 92
CVR-nr: 25695771
www.topotarget.com

To the Copenhagen Stock Exchange
Announcement No. 23-07 / Copenhagen 26 June 2007 

Report pursuant to the Danish Securities Trading Act, Section 28a

Copenhagen - 26 June 2007 - Pursuant to the Danish Securities Trading Act,
Section 28a TopoTarget A/S (Copenhagen Stock Exchange: TOPO) is obliged to
report on transactions by members of its senior management and their related
parties in shares issued by TopoTarget A/S and related securities. 

Name	                  Peter Buhl Jensen
Reason	                  CEO
Issuer and ISIN code	TopoTarget A/S, DK0060086072
Transaction	         Purchase
Trade date	         25 June 2007
Market	                  Copenhagen Stock Exchange
Number	                  10,010
Market value in DKK        300,300

Name	                  Leif Hamø
Reason	                  CFO
Issuer and ISIN code	TopoTarget A/S, DK0060086072
Transaction	         Purchase
Trade date	         25 June 2007
Market	                  Copenhagen Stock Exchange
Number	                  26,677
Market value in DKK	800,310

TopoTarget A/S
 
For further information, please contact:

Dr. Peter Buhl Jensen		Telephone	 +45 39 17 83 41
Chief Executive Officer		Mobile	 +45 21 60 89 22

Background information

About TopoTarget
TopoTarget (OMX - The Nordic Exchange: TOPO) is a biopharmaceutical company,
headquartered in Denmark and with subsidiaries in the UK, Germany and the USA,
dedicated to finding ''Answers for Cancer'' and developing improved cancer
therapies. TopoTarget is founded and run by clinical cancer specialists and
combines years of hands-on clinical experience with in-depth understanding of
the molecular mechanisms of cancer. Focus lies on highly predictive cancer
models and key cancer enzyme regula-tors (mainly HDAC, mTOR, and topoisomerase
II inhibitors) and a strong development foundation has been built. TopoTarget
has a broad portfolio of small molecule preclini-cal drug candidates and seven
drugs are in clinical development, including both novel anti-cancer
therapeutics and new cancer indications for existing drugs. Savene™ is
TopoTarget's first product on the market. In addition to organic growth,
TopoTarget consistently looks for opportunities to strengthen and expand its
activities through acquisitions and in-licensing. For more information, please
refer to www.topotarget.com.

Attachments

announcement no. 23 07 28a 26 june 2007.pdf