Express Scripts Reports Strong Second Quarter Earnings

Company Raises 2007 Earnings Per Share Guidance; Announces Increase in Share Repurchase Authorization


ST. LOUIS, July 25, 2007 (PRIME NEWSWIRE) -- Express Scripts, Inc. (Nasdaq:ESRX) announced second quarter net income of $152.7 million, or $0.57 per diluted share. Excluding a non-recurring gain on the sale of stock that is discussed below, earnings per diluted share was $0.56, a 47 percent increase over $0.38 per diluted share for the same quarter last year. All per share amounts have been adjusted to reflect the Company's 2-for-1 stock split, which was effective June 22, 2007.

During the quarter, Express Scripts repurchased 17.0 million shares of common stock (on a split-adjusted basis) for $826.7 million, and to date, the Company has repurchased 100.7 million shares. The Board approved an increase in the share repurchase program by an additional 8 million shares to an aggregate program of 120 million shares. The Company reported year-to-date cash flow from operations of $251.3 million compared to $193.8 million for the same period last year, and is on track to generate $750 to $850 million for the year.

"Our formulary strategy reinforces our business model, which is built around alignment of interests with plan sponsors and patients," stated George Paz, president, chief executive officer and chairman. "We demonstrated the power of teaming up with plan sponsors and patients to move market share to generics and lower-cost preferred drugs. Together, we seized opportunities to lower the cost of prescription drugs, and at the same time, changed the marketplace."

Second Quarter Review

Generic utilization reached a record 61.1 percent compared to 56.3 percent last year. Total adjusted claims for the quarter were 126.0 million. Retail network claims processed in the second quarter were 94.1 million, home delivery claims were 10.2 million, and Specialty and Ancillary Services ("SAAS") claims were 1.2 million.

Gross profit for the second quarter increased 22 percent to $443.4 million from $363.6 million last year. The increase reflects higher generic utilization and lower retail and home delivery drug purchasing costs. Gross profit per adjusted claim was a record $3.52, a 25 percent increase over $2.81 for the same quarter last year.

Operating income increased 35 percent to $260.3 million from $192.5 million last year. Operating income for the SAAS segment decreased $5.9 million sequentially from $16.4 million in the first quarter of 2007 to $10.5 million in the second quarter. This decrease was due to a $4.0 million charge to bad debt expense in the infusion business and normal seasonality in the mix of drugs dispensed in the specialty pharmacy. The Company believes that the combination of its PBM and specialty offerings provides a cost-effective single source solution for its clients, and contributed to strong operating income in the PBM segment, which increased 47 percent to $249.8 million compared to $169.9 million last year.

Higher generic utilization and lower retail and home delivery drug purchasing costs translated into strong EBITDA growth. EBITDA increased 31 percent to $286.5 million from $218.6 million last year and reached a record $2.27 per adjusted claim, a 34 percent increase over $1.69 last year.

During the quarter, the Company recorded a non-recurring gain of $4.2 million ($2.7 million, net of tax), or $0.01 per diluted share resulting from the sale of its CVS/Caremark shares in April 2007.

2007 Earnings Guidance

Changes to the Average Wholesale Price ("AWP") drug pricing benchmark required by a settlement of a class action suit against a drug price reporting service are no longer expected to take effect in 2007. As a result, the Company is eliminating the allowance for the potential impact of the AWP settlement in its current earnings forecast.

After eliminating the allowance for AWP changes that the Company had previously announced and further evaluating the strong underlying trends in the business, the Company is raising its previous 2007 diluted earnings per share guidance from a range of $2.15 to $2.21 to a range of $2.23 to $2.29. This guidance range excludes the non-recurring items identified in Tables 3 and 4 below.

Express Scripts, Inc. is one of the largest PBM companies in North America, providing PBM services to over 50 million members through thousands of client groups, including managed-care organizations, insurance carriers, employers, third-party administrators, public sector, workers compensation, and union-sponsored benefit plans.

Express Scripts provides integrated PBM services, including network-pharmacy claims processing, home delivery services, benefit-design consultation, drug-utilization review, formulary management, disease management, and medical- and drug-data analysis services. The Company also distributes a full range of injectable and infusion biopharmaceutical products directly to patients or their physicians, and provides extensive cost-management and patient-care services.

Express Scripts is headquartered in St. Louis, Missouri. More information can be found at http://www.express-scripts.com, which includes expanded investor information and resources.

SAFE HARBOR STATEMENT

This press release contains forward-looking statements, including, but not limited to, statements related to the Company's plans, objectives, expectations (financial and otherwise) or intentions. Actual results may differ significantly from those projected or suggested in any forward-looking statements. Factors that may impact these forward-looking statements include but are not limited to:



 * uncertainties associated with our acquisitions, which include
   integration risks and costs, uncertainties associated with client
   retention and repricing of client contracts, and uncertainties
   associated with the operations of acquired businesses
 * costs and uncertainties of adverse results in litigation, including
   a number of pending class action cases that challenge certain of
   our business practices
 * investigations of certain PBM practices and pharmaceutical pricing,
   marketing and distribution practices currently being conducted by
   the U.S. Attorney offices in Boston, and by other regulatory
   agencies including the Department of Labor, and various state
   attorneys general
 * changes in industry pricing benchmarks such as average wholesale
   price ("AWP") and average manufacturer price ("AMP") , which could
   have the effect of reducing prices and margins, including the
   impact of a proposed settlement in a class action case involving
   First DataBank, an AWP reporting service
 * uncertainties regarding the implementation of the Medicare Part D
   prescription drug benefit, including the financial impact to us to
   the extent that we participate in the program on a risk-bearing
   basis, uncertainties of client or member losses to other providers
   under Medicare Part D, and increased regulatory risk
 * uncertainties associated with U.S. Centers for Medicare &
   Medicaid's ("CMS") implementation of the Medicare Part B
   Competitive Acquisition Program ("CAP"), including the potential
   loss of clients/revenues to providers choosing to participate in
   the CAP
 * increased compliance relating to our contracts with the DoD TRICARE
   Management Activity and various state governments and agencies
 * our ability to maintain growth rates, or to control operating or
   capital costs
 * continued pressure on margins resulting from client demands for
   lower prices, enhanced service offerings and/or higher service
   levels, and the possible termination of, or unfavorable
   modification to, contracts with key clients or providers
 * competition in the PBM and specialty pharmacy industries, and our
   ability to consummate contract negotiations with prospective
   clients, as well as competition from new competitors offering
   services that may in whole or in part replace services that we now
   provide to our customers
 * results in regulatory matters, the adoption of new legislation or
   regulations (including increased costs associated with compliance
   with new laws and regulations), more aggressive enforcement of
   existing legislation or regulations, or a change in the
   interpretation of existing legislation or regulations
 * the possible loss, or adverse modification of the terms, of
   relationships with pharmaceutical manufacturers, or changes in
   pricing, discount or other practices of pharmaceutical
   manufacturers or interruption of the supply of any pharmaceutical
   products
 * the possible loss, or adverse modification of the terms, of
   contracts with pharmacies in our retail pharmacy network
 * the use and protection of the intellectual property we use in our
   business
 * our leverage and debt service obligations, including the effect of
   certain covenants in our borrowing agreements
 * our ability to continue to develop new products, services and
   delivery channels
 * general developments in the health care industry, including the
   impact of increases in health care costs, changes in drug
   utilization and cost patterns and introductions of new drugs
 * increase in credit risk relative to our clients due to adverse
   economic trends
 * our ability to attract and retain qualified personnel
 * other risks described from time to time in our filings with the SEC

We do not undertake any obligation to release publicly any revisions to such forward-looking statements to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.



                         EXPRESS SCRIPTS, INC.
            Unaudited Consolidated Statement of Operations

                         Three months ended       Six months ended
                              June 30,                June 30,
                       ----------------------  ----------------------
 (in millions, except
  per share data)         2007        2006        2007        2006
                       ----------  ----------  ----------  ----------

 Revenues (1)          $ 4,600.4   $ 4,421.1   $ 9,139.9   $ 8,801.1
 Cost of revenues (1)    4,157.0     4,057.5     8,270.4     8,092.9
                       ----------  ----------  ----------  ----------
  Gross profit             443.4       363.6       869.5       708.2
 Selling, general and
  administrative           183.1       171.1       355.8       332.2
                       ----------  ----------  ----------  ----------
 Operating income          260.3       192.5       513.7       376.0
                       ----------  ----------  ----------  ----------
 Other (expense)
  income:
  Non-operating gains
   (charges), net            4.2          --       (18.8)         --
  Undistributed loss
   from joint venture       (0.4)       (0.3)       (0.8)       (0.8)
  Interest income            2.6         4.0         5.4         9.0
  Interest expense         (25.6)      (23.7)      (47.8)      (44.2)
                       ----------  ----------  ----------  ----------
                           (19.2)      (20.0)      (62.0)      (36.0)
                       ----------  ----------  ----------  ----------
 Income before income
  taxes                    241.1       172.5       451.7       340.0
 Provision for income
  taxes                     88.4        64.7       165.3       127.5
                       ----------  ----------  ----------  ----------
 Net income            $   152.7   $   107.8   $   286.4       212.5
                       ==========  ==========  ==========  ==========
 Basic earnings per
  share                $    0.58   $    0.38   $    1.07   $    0.74
                       ==========  ==========  ==========  ==========
 Weighted average
  number of common
  shares outstanding
   during the period
   - Basic EPS             263.6       282.4       267.6       287.6
                       ==========  ==========  ==========  ==========
 Diluted earnings per
  share                $    0.57   $    0.38   $    1.06   $    0.73
                       ==========  ==========  ==========  ==========
 Weighted average
  number of common
  shares outstanding
   during the period
   - Diluted EPS           267.0       286.8       271.1       292.4
                       ==========  ==========  ==========  ==========

 (1) Excludes estimated retail pharmacy co-payments of $943.9 and
 $1,045.7 for the three months ended June 30, 2007 and 2006,
 respectively and $1,932.1 and $2,266.5 for the six months ended
 June 30, 2007 and 2006, respectively.  These are amounts we
 instructed retail pharmacies to collect from members.  We have no
 information regarding actual co-payments collected.


                            EXPRESS SCRIPTS, INC.
                 Unaudited Consolidated Balance Sheet

                                                June 30,  December 31,
 (in millions, except share data)                 2007        2006

 Assets                                       -----------  -----------
 Current assets:
  Cash and cash equivalents                   $    111.2   $    131.0
  Receivables, net                               1,303.9      1,334.4
  Inventories                                      198.4        194.6
  Deferred taxes                                   107.1         90.9
  Prepaid expenses and other current assets         24.2         21.2
                                              -----------  -----------
   Total current assets                          1,744.8      1,772.1
 Property and equipment, net                       198.5        201.4
 Goodwill                                        2,688.0      2,686.0
 Other intangible assets, net                      360.5        378.4
 Other assets                                       41.1         70.2
                                              -----------  -----------
   Total assets                               $  5,032.9   $  5,108.1
                                              ===========  ===========
 Liabilities and Stockholders' Equity
 Current liabilities:
  Claims and rebates payable                  $  1,198.3   $  1,275.7
  Accounts payable                                 570.2        583.4
  Accrued expenses                                 346.4        390.2
  Current maturities of long-term debt             220.1        180.1
                                              -----------  -----------
   Total current liabilities                     2,335.0      2,429.4
 Long-term debt                                  1,700.3      1,270.4
 Other liabilities                                 310.2        283.4
                                              -----------  -----------
   Total liabilities                             4,345.5      3,983.2
                                              -----------  -----------
 Stockholders' equity:
 Preferred stock, 5,000,000 shares
  authorized, $0.01 par value per share;
  and no shares issued and outstanding                --           --
 Common stock, 1,300,000,000 shares
  authorized, $0.01 par value per share;
  shares issued: 318,867,000 and 159,442,000,
  respectively; shares outstanding:
  257,851,000 and 135,650,000, respectively          3.2          1.6
 Additional paid-in capital                        538.1        495.3
 Accumulated other comprehensive income             15.0         11.9
 Retained earnings                               2,303.5      2,017.3
                                              -----------  -----------
                                                 2,859.8      2,526.1
 Common stock in treasury at cost,
  61,016,000 and 23,792,000 shares,
  respectively                                  (2,172.4)    (1,401.2)
                                              -----------  -----------
   Total stockholders' equity                      687.4      1,124.9
                                              -----------  -----------
   Total liabilities and stockholders'
    equity                                    $  5,032.9   $  5,108.1
                                              ===========  ===========

                         EXPRESS SCRIPTS, INC.
            Unaudited Consolidated Statement of Cash Flows

                                                     Six months ended
                                                         June 30,
                                                  --------------------
 (in millions)                                       2007       2006
                                                  ---------  ---------
 Cash flow from operating activities:
 Net income                                       $  286.4   $  212.5
  Adjustments to reconcile net income to
   net cash provided by operating
  activities:
   Depreciation and amortization                      52.1       51.9
   Non-cash adjustments to net income                 23.5       13.4
   Changes in operating assets and liabilities:
    Claims and rebates payable                       (77.4)    (175.8)
    Other net changes in operating assets and
     liabilities                                     (33.3)      91.8
                                                  ---------  ---------
 Net cash provided by operating activities           251.3      193.8
                                                  ---------  ---------
 Cash flows from investing activities:
  Purchases of property and equipment                (29.9)    ( 20.7)
  Sale of marketable securities                       34.2         --
  Other                                               (0.6)      (0.1)
                                                  ---------  ---------
 Net cash provided by (used in) investing
  activities                                           3.7      (20.8)
                                                  ---------  ---------

 Cash flows from financing activities:
  Proceeds from long-term debt                       600.0         --
  Repayment of long-term debt                        (80.1)     (80.1)
  Repayments of revolving credit line, net           (50.0)     285.0
  Tax benefit relating to employee stock
   compensation                                       39.3       27.5
  Treasury stock acquired                           (826.7)    (707.7)
  Net proceeds from employee stock plans              42.1       19.7
  Deferred financing fees                             (1.3)      (0.3)
                                                  ---------  ---------
 Net cash used in financing activities              (276.7)    (455.9)
                                                  ---------  ---------

 Effect of foreign currency translation adjustment     1.9        0.9
                                                  ---------  ---------
 Net decrease in cash and cash equivalents           (19.8)    (282.0)
 Cash and cash equivalents at beginning of period    131.0      477.9
                                                  ---------  ---------
 Cash and cash equivalents at end of period       $  111.2   $  195.9
                                                  =========  =========


                           EXPRESS SCRIPTS, INC.
       (in millions, except per claim, per share and ratio data)
                                Table 1
                           Unaudited Operating Statistics

                   3 months  3 months   3 months  3 months  3 months
                    ended     ended      ended     ended     ended
                   6/30/2007 3/31/2007 12/31/2006 9/30/2006 6/30/2006
                   --------- --------- ---------- --------- ---------
 Revenues
 --------
 PBM (1)            3,669.3   3,608.9   3,626.3   3,465.1   3,528.4
 SAAS                 931.1     930.6     902.4     865.1     892.7
                   --------- --------- --------- --------- ---------
   Total
    consolidated
    revenues        4,600.4   4,539.5   4,528.7   4,330.2   4,421.1
                   ========= ========= ========= ========  =========

 Claims Detail
 -------------
 Network (2)           94.1      96.8      97.8      93.2      96.9
 Home delivery         10.2      10.0      10.3      10.2      10.4
                   --------- --------- --------- --------- ---------
  Total PBM claims    104.3     106.8     108.1     103.4     107.3
                   --------- --------- --------- --------- ---------
  Adjusted PBM
   claims (3)         124.8     126.8     128.7     123.8     128.1
                   --------- --------- --------- --------- ---------
 SAAS claims (4)        1.2       1.2       1.3       1.3       1.5
                   --------- --------- --------- --------- ---------
  Total adjusted
   claims (5)         126.0     128.0     130.0     125.1     129.6
                   ========= ========= ========= ========  =========

 Per Adjusted Claim
 ------------------
 Adjusted Gross
  profit           $   3.52  $   3.26  $   3.19  $   2.99  $   2.81
 Adjusted EBITDA   $   2.27  $   2.11  $   2.06  $   1.84  $   1.69

                            Selected Ratio Analysis
                                    Table 2

                     As of     As of     As of      As of     As of
                   6/30/2007 3/31/2007 12/31/2006 9/30/2006 6/30/2006
                   --------- --------- ---------- --------- ---------
 Debt to EBITDA
  ratio (7)             1.8x      1.4x      1.6x      1.9x      2.1x
 EBITDA interest
  coverage (8)         10.7x     10.2x      9.7x      9.4x     11.5x
 Operating cash
  flow interest
  coverage (9)          7.2x      7.9x      6.9x      6.6x      9.3x
 Debt to
  capitalization (10)  73.6%     51.4%     56.3%     62.7%     62.4%

 See Notes to Unaudited Operating Statistics and Selected Ratio
 Analysis


           Unaudited Earnings Excluding Non-recurring Items
                              Table 3

                               3 months  3 months  6 months   6 months
                                ended      ended     ended     ended
                              6/30/2007  6/30/2006 6/30/2007 6/30/2006
                              ---------  --------- --------- ---------

 Reported income before taxes   $ 241.1   $ 172.5   $ 451.7   $ 340.0
  Transaction costs for
   terminated proposal to
   acquire Caremark, less
   special dividend received on
   Caremark stock and gain on
   sale of Caremark stock          (4.2)    --         18.8        --
  Settlement of contractual
   item with supply chain
   vendor                          --       --         (9.0)       --
                              ---------  --------- --------- ---------
 Income before taxes excluding
  net non-recurring charges       236.9     172.5     461.5     340.0

 Adjusted provision for
  income taxes                     86.9      64.7     168.9     127.5
                              ---------  --------- --------- ---------
 Net income excluding net
  non-recurring charges         $ 150.0   $ 107.8   $ 292.6   $ 212.5
                              =========  ========= ========= =========

 Weighted average number of
  shares outstanding during
  period - diluted                267.0     286.8     271.1     292.4

 Diluted earnings per share
  excluding net charges         $  0.56  $   0.38   $  1.08   $  0.73

 Diluted earnings per share
  as reported                      0.57      0.38      1.06      0.73
                              ---------  --------- --------- ---------

 Impact of non-recurring items  $  0.01   $ (0.00)  $ (0.02)  $ (0.00)

 The Company is providing diluted earnings per share excluding the
 impact of certain charges in order to compare the underlying
 financial performance to prior periods.


       Earnings Guidance Forecast Excluding Non-recurring Items
                                Table 4

                                               For the year ended
                                                December 31, 2007
                                                -----------------
 Earnings guidance range, including net
  non-recurring charges                         $ 2.21 to $ 2.27

 Impact of non-recurring items per Table 3        0.02      0.02
                                                -------   -------
 Earnings guidance range, excluding net
  non-recurring charges                         $ 2.23 to $ 2.29
                                                =======   =======

                         EXPRESS SCRIPTS, INC.

   Notes to Unaudited Operating Statistics and Selected Ratio Analysis
                             (in millions)

 (1) We have reclassified certain amounts deemed immaterial between
 PBM revenue and PBM cost of revenue.  There is no effect on
 Consolidated Gross Profit.

 (2) Network claims exclude drug formulary only claims where we only
 administer the clients formulary and approximately 0.5 million manual
 claims per quarter.

 (3) PBM adjusted claims represent network claims plus mail claims,
 which are multiplied by 3, as mail claims are typically 90 day claims
 and network claims are generally 30 day claims.  Adjusted claims
 calculated from the table may differ due to rounding.

 (4) Specialty and Ancillary Services (SAAS) claims represent the
 distribution of pharmaceuticals through Patient Assistance Programs
 and the distribution of pharmaceuticals where we have been selected
 by the pharmaceutical manufacturer as part of a limited distribution
 network.  They also represent the distribution of specialty drugs
 through our CuraScript subsidiary.

 (5) Total adjusted claims includes PBM adjusted claims plus SAAS
 claims.

 (6) The following is a reconciliation of EBITDA to net income and to
 net cash provided by operating activities as the Company believes
 they are the most directly comparable measures calculated under
 Generally Accepted Accounting Principles:

                                  3 months ended     6 months ended
                                     June 30,            June 30,
                               ------------------- -------------------
                                 2007       2006     2007       2006
                               --------- --------- --------- ---------
 Net income                    $  152.7  $  107.8  $  286.4  $  212.5
   Income taxes                    88.4      64.7     165.3     127.5
   Depreciation and
    amortization *                 26.2      26.1      52.1      51.9
   Interest expense, net           23.0      19.7      42.4      35.2
   Undistributed loss from
    joint venture                   0.4       0.3       0.8       0.8
   Non-operating charges, net      (4.2)       --      18.8        --
                               --------- --------- --------- ---------
 EBITDA                           286.5     218.6     565.8     427.9
   Current income taxes           (87.4)    (71.4)   (170.9)   (132.9)
   Interest expense less
    amortization                  (22.5)    (19.2)    (41.4)    (34.2)
   Undistributed loss from
    joint venture                  (0.4)     (0.3)     (0.8)     (0.8)
   Non-operating charges, net       4.2        --     (18.8)       --
   Other adjustments to
    reconcile net income to
    net cash provided by
    operating activities          (84.7)     25.1     (82.6)    (66.2)
                               --------- --------- --------- ---------
 Net cash provided by
  operating activities         $   95.7  $  152.8  $  251.3  $  193.8
                               ========= ========= ========= =========

 EBITDA is earnings before other income (expense), interest, taxes,
 depreciation and amortization, or operating income plus depreciation
 and amortization.  EBITDA is presented because it is a widely
 accepted indicator of a company's ability to service indebtedness and
 is frequently used to evaluate a company's performance.  EBITDA,
 however, should not be considered as an alternative to net income, as
 a measure of operating performance, as an alternative to cash flow,
 as a measure of liquidity or as a substitute for any other measure
 computed in accordance with accounting principles generally accepted
 in the United States. In addition, our definition and calculation of
 EBITDA may not be comparable to that used by other companies.

 * Includes depreciation and amortization expense of:
     Gross profit                   8.8       9.3      17.9      18.4
     Selling, general and
      administrative               17.4      16.8      34.2      33.5
                               --------- --------- --------- ---------
                                   26.2      26.1      52.1      51.9
                               ========= ========= ========= =========

 (7) Represents debt as of the balance sheet date divided by EBITDA
 for the twelve months ended.

 (8) Represents EBITDA for the twelve months ended divided by interest
 expense for the twelve months ended.

 (9) Represents Operating Cash Flow for the twelve months ended
 divided by interest expense for the twelve months ended.

 (10) Represents debt divided by the total of debt and stockholders
 equity.


            

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