Novo Nordisk, reduction in face value with effect from 3 December 2007


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|                                      |          Copenhagen, 23 November 2007 |
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Novo Nordisk A/S - reduction in face value                                      

The face value and ISIN of the following share will be changed with effect from 
3 December 2007:                                                                

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| ISIN                     | New ISIN              | Name                      |
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| DK0010280817             | DK0060102614          | Novo Nordisk B            |
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The face value will be reduced from DKK 2 to DKK 1.                             

The price information which is dependent on the face value will be adjusted to  
reflect the new face value.                                                     

For further information, please contact: Asta Jepsen, Surveillance, tel. +45 33 
93 33 66                                                                        
ISIN: DK0060102614 (VP: 6010261)                                                

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| Name:                               | Novo Nordisk B                         |
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| Volume before change:               | 269,736,400 shares of DKK 2 (DKK       |
|                                     | 539,472,800)                           |
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| Volume after change:                | 539,472,800 shares of DKK 1 (DKK       |
|                                     | 539,472,800)                           |
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| Face value:                         | DKK 1                                  |
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| Short name:                         | NOVO B                                 |
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| Share type:                         | AKTIE                                  |
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GENERAL INFORMATION                                                             

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| Name/bearer:                        | Bearer                                 |
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| Voting rights on listed shares:     | Limited                                |
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| Financial year:                     | 1 January - 31 December                |
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| Unlisted capital:                   | DKK 107,487,200 of A shares            |
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| Issuing bank:                       | Danske Bank A/S                        |
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| Changed trading lot:                | 50                                     |
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| CBR no.:                            | 24 25 67 90                            |
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| GICS:                               | 35 20 20 10                            |
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| Type:                               | 11                                     |
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Attachments

novo nordisk - ny aktiestrrelse - uk.pdf