QIAGEN Reports Strong Fourth Quarter and Fiscal 2007 Results




 * 34% Constant Currency and 12% Organic Revenue Growth in 2007
 * 31% Growth in Adjusted Net Income in 2007
 * Fourth Quarter 2007 Adjusted EPS Exceeds Guidance by $0.02
 * Guidance 2008: Revenues $875 to $905 million (growth rate 35% to 40%)
                  Adj. EPS $0.76 to $0.80

VENLO, The Netherlands, Feb. 11, 2008 (PRIME NEWSWIRE) -- QIAGEN N.V. (Nasdaq:QGEN) (Frankfurt:QIA) today announced the results of operations for the fourth quarter and the fiscal year ended December 31, 2007.

The reported net sales and adjusted earnings per share for the fourth quarter and fiscal 2007 exceeded the guidance provided by the Company on November 11, 2007.

QIAGEN's fourth quarter and fiscal 2007 results include the results of operations of Digene Corporation and eGene, Inc. from the dates of acquisition as well as charges related to these acquisitions.

Fourth Quarter 2007 Results

The Company reported that consolidated net sales for its fourth quarter 2007 increased 67% to $210.2 million from $125.9 million for the same quarter in 2006. Reported operating income for the quarter decreased 7% to $25.0 million from $26.9 million in the same quarter of 2006, and net income for the quarter decreased 23% to $15.0 million from $19.4 million in the same quarter of 2006. Diluted earnings per share for the fourth quarter decreased to $0.07 in 2007 (based on 205.2 million weighted average shares and share equivalents outstanding) from $0.13 in 2006 (based on 154.8 million weighted average shares and share equivalents outstanding).

On an adjusted basis, fourth quarter operating income increased 55% to $51.8 million in 2007 from $33.5 million in 2006, and fourth quarter 2007 adjusted net income increased 31% to $32.0 million from $24.4 million in 2006. Adjusted diluted earnings per share were $0.16 in both the fourth quarter 2007 and 2006.



 ---------------------------------------------------------------------
 QIAGEN's Fiscal 2007 (in US$ millions, except per share information)
 ---------------------------------------------------------------------
                                       FY 2007    FY 2006    Growth
 ---------------------------------------------------------------------
 Net sales                              649.8      465.8       40%
 Operating income, adj.(1)              164.3      120.9       36%
 Net income, adj.(1)                    111.5       85.3       31%
 EPS, adj.(1) (US$)                      0.63       0.56       13%
 ---------------------------------------------------------------------

 (1) excluding acquisition, integration and restructuring related
     charges as well as amortization of acquired IP and
     equity-based compensation (SFAS 123R) as detailed in the
     table below.

Fiscal Year 2007 Results

For the year ended December 31, 2007, net sales increased 40% to $649.8 million compared to $465.8 million in 2006. Operating income as reported for fiscal 2007 decreased 17% to $83.1 million from $100.6 million for 2006, and net income decreased 29% to $50.1 million in 2007 from $70.5 million in 2006, and diluted earnings per share decreased to $0.28 in 2007 from $0.46 in 2006.

On an adjusted basis, operating income for the year ended December 31, 2007 increased 36% to $164.3 million from $120.9 million in 2006, and adjusted net income increased 31% to $111.5 million in 2007 from $85.3 million in 2006. Adjusted diluted earnings per share for the year ended December 31, 2007 increased 13% to $0.63 per share, from $0.56 per share in 2006.

QIAGEN has regularly reported adjusted results to give an additional insight into its financial performance. Adjusted results should be considered in addition to the reported results prepared in accordance with generally accepted accounting principles, but should not be considered a substitute. The Company believes certain items should be excluded from adjusted results when they are either outside of our ongoing core operations or vary significantly from period to period, which affects the comparability of results with the Company's competitors and its own prior periods. Costs and charges excluded from adjusted results include acquisition, integration, restructuring and related costs, acquisition-related amortization, and compensation cost due to equity based compensation in accordance with Statement of Financial Accounting Standards No. 123 (Revised) (SFAS 123R).



 ---------------------------------------------------------------------
 QIAGEN's Adjustments to Gross Profit, Operating Income,
 Net Income and EPS
 ---------------------------------------------------------------------
 In US$ millions
  unless indicated    Q4 2007       Q4 2006     FY 2007      FY 2006
 ---------------------------------------------------------------------

 Gross profit
  reported                138.8         86.4        433.6        318.5
 Acquisition related
  charges                   1.5          0.3          2.8          2.1
 Amortization of
  acquired IP              11.4          1.8         23.6          6.1
 SFAS 123R impact           0.3          0.0          0.4          0.0
 Gross profit,
  adjusted                152.0         88.5        460.4        326.7

 Operating income,
  reported                 25.0         26.9         83.1        100.6
 Acquisition and
  integration related
  charges (incl. COS)       9.6          1.4         17.6          8.1
 Purchased in-process
  research &
  development               0.0          1.9         25.9          2.2
 Relocation and
  restructuring
  charges                   0.0          0.7          0.6          1.5
 Amortization of
  acquired IP
  (incl. COS)              14.8          2.5         31.3          8.2
 SFAS 123R impact
  (incl. COS)               2.4          0.1          5.8          0.3
 Operating income,
  adjusted                 51.8         33.5        164.3        120.9

 Net income, reported      15.0         19.4         50.1         70.5
 Acquisition and
  integration
  related charges           6.1          1.0         11.3          6.1
 Purchased in-process
  research &
  development               0.0          1.9         25.9          2.2
 Relocation and
  restructuring
  charges                   0.0          0.5          0.4          1.0
 Amortization of
  acquired IP               9.4          1.6         20.0          5.3
 SFAS 123R impact           1.5          0.0          3.8          0.2
 Net income, adjusted      32.0         24.4        111.5         85.3

 Weighted average
  number of basic
  common shares     194,852,000  150,009,000  168,457,000  149,504,000
 Weighted average
  number of diluted
  common shares     205,233,000  154,783,000  175,959,000  153,517,000
 EPS, reported in
  US$                      0.07         0.13         0.28         0.46
 EPS, adjusted in
  US$                      0.16         0.16         0.63         0.56
 ---------------------------------------------------------------------

"2007 was a very successful year for QIAGEN. We executed on our strategy and significantly increased our technology and market leadership in sample and assay technologies in all of our customer segments," said Peer Schatz, QIAGEN's Chief Executive Officer. "In particular, the integration of the rapidly growing QIAGEN molecular diagnostics business with Digene's in terms of size and growth comparable molecular diagnostics leadership in HPV testing resulted in a very strong leadership position for QIAGEN in molecular diagnostics overall. Molecular diagnostics today represents about 50% of our current sales and presents a very strong growth outlook.

"The launches of 72 new products in 2007 contributed 4% to 2007 net sales growth. This result is another demonstration of the success of QIAGEN's innovation strategy. New products included innovative sample and assay technologies for research in the areas of epigenetics, gene expression, micro RNA, proteomics, RNAi, applied testing and molecular diagnostics as well as innovative platform solutions such as the very successful QIAcube. Our full pipeline of new products and a strong strategic position build a solid basis for our success in 2008 and beyond.

"We expect a number of exciting new market introductions in 2008. These include a further expansion of our sample and assay technology portfolio for research in applied testing and molecular diagnostics. We are significantly investing in clinical trials for a number of molecular diagnostic products with the goal of adding more regulated products to our portfolio," Mr. Schatz added. "Our pipeline of automated solutions for our sample and assay technologies is exceptionally strong. The major launch within this portfolio was the launch of QIAsymphonySP in January -- the first module of a novel modular processing platform which can integrate entire workflows in molecular processing. QIAsymphony is already generating a lot of excitement and has the potential to bring significant value to our customers.

"Our acquisition strategy remained focused, consistent and value-creating, providing complementary technologies, new commercial capabilities and/or geographic reach. With the acquisition of Digene we added an exciting new product portfolio in women's health to our molecular diagnostics franchise, which approximated Digene's size and growth rates prior to the acquisition. This acquisition catapulted QIAGEN into a fast growing leadership position for sample and assay technologies in molecular diagnostics (excluding viral load and blood banking). Our assay portfolio is considered to be the broadest and our sales and marketing force in molecular diagnostics the most powerful in the industry.

"Even more exciting, we achieved our strong financial results in 2007 while experiencing significant strategic momentum and executing on a significant integration effort. I want to thank our employees around the world for their contributions to our performance in 2007 and to building long-term success and leadership for QIAGEN."

"QIAGEN experienced an exciting fourth quarter and fiscal year 2007. Reported revenues and adjusted earnings per share exceeded our increased guidance and reflected our good progress in integrating acquired businesses," said Roland Sackers, QIAGEN's Chief Financial Officer. "Revenue growth for the full year was 40% and was fueled by strong organic growth of 12% and positive contribution of 22% from acquisitions. Our consumable portfolio contributed 34% growth at constant exchange rates in 2007.

"QIAGEN's instrumentation products showed a very strong growth rate at constant exchange rates of 35% in 2007," Mr. Sackers continued. "Net sales for the fiscal year 2007 recorded in North America represented approximately 46% of our overall business and recorded a growth rate of 47% whereby European sales, which represent approximately 41% of our revenues, showed a growth rate of approximately 21% at constant exchange rates. Net sales in Asia showed a very strong growth rate of 39% at constant exchange rates in fiscal 2007 driven by a strong demand primarily in molecular diagnostics."

Guidance for 2008

QIAGEN expects revenues between $875 and $905 million in 2008 representing a revenue growth rate between 35% and 40% when compared to 2007 and adjusted diluted earnings per share between $0.76 and $0.80. The Company will provide detailed guidance in the Company's conference call on February 12, 2008.

Detailed information on the Company's business and financial performance will be presented in the Company's conference call on February 12, 2008 at 9:30 a.m. ET. The corresponding presentation slides will be available for download on the Company's website at www.qiagen.com/goto/120208. A webcast of the conference call will be available on the same website at www.qiagen.com/goto/120208.

QIAGEN -- Sample and Assay Technologies Highlights:



 * QIAGEN introduced QIAsymphony SP, the first system of a novel
   modular processing platform which can be integrated to automate
   entire workflows -- from sample to result. The QIAsymphony offers
   highest flexibility, convenience and safety for a broad range of
   sample and assay applications.

 * QIAGEN and BioOne* Capital entered into an joint venture to
   establish Dx Assay Pte Ltd one of the first centers in Singapore for
   assay development in which molecular diagnostics for infectious and
   genetic diseases will be developed.

 * QIAGEN has been awarded an exclusive contract by the Singapore
   Ministry of Health to supply sample preparation solutions and
   molecular tests for the specific detection of Influenza H5N1 viruses
   (avian flu virus). The contract with the Singapore Ministry of
   Health is the latest supply agreement of QIAGEN with public and
   private institutions engaged in H5N1 surveillance. More than 80
   institutes worldwide involved in the surveillance of avian flu
   infection use procedures and reagents developed and offered by
   QIAGEN.

 ---------------------------------------------------------------------
 QIAGEN's Fiscal 2007 at Constant Currencies
 ---------------------------------------------------------------------
                                  2007                 Growth Rates
 As percentage         2007        FY      2006     -------------------
  of net sales,         FY      Constant    FY                Constant
  unless indicated    Reported  Currency  Reported  Reported  Currency
 ---------------------------------------------------------------------
 Consumables            89%        89%       89%       40%       34%
 Instruments            10%        10%       10%       40%       35%
 Others                  1%         1%        1%       30%       22%
 ---------------------------------------------------------------------
 Total revenues        100%       100%      100%       40%       34%
 ---------------------------------------------------------------------

 Gross margin           67%        67%       68%       36%       32%
 Gross margin, adj.(1)  71%        71%       70%       41%       36%

 Operating income
  margin                13%        13%       22%      -17%      -20%
 Operating income
  margin, adj.(1)       25%        26%       26%       36%       33%

 Net income margin       8%         8%       15%      -29%      -32%
 Net income margin,
  adj.(1)               17%        17%       18%       31%       28%

 EPS in US$ per
  share               0.28       0.27      0.46       -39%      -41%
 EPS in US$ per
  share, adj.(1)      0.63       0.62      0.56        13%       11%

 ---------------------------------------------------------------------
 (1) excluding acquisition, integration and restructuring related
     charges as well as amortization of acquired IP and equity-based
     compensation (SFAS 123R) as detailed in the table above.

About QIAGEN:

QIAGEN N.V., a Netherlands holding company, is the leading provider of innovative sample and assay technologies and products. QIAGEN's products are considered standards in areas such as pre-analytical sample preparation and assay solutions in research for life sciences, applied testing and molecular diagnostics. QIAGEN has developed a comprehensive portfolio of more than 500 proprietary, consumable products and automated solutions for sample collection, nucleic acid and protein handling, separation, and purification and open and target specific assays. The company's products are sold to academic research markets, to leading pharmaceutical and biotechnology companies, to applied testing customers (such as in forensics, veterinary, biodefense and industrial applications) as well as to molecular diagnostics laboratories. QIAGEN employs more than 2,600 people worldwide. QIAGEN products are sold through a dedicated sales force and a global network of distributors in more than 40 countries. Further information about QIAGEN can be found at www.qiagen.com.

The QIAGEN N.V. logo is available at http://www.primenewswire.com/newsroom/prs/?pkgid=3692

Certain of the statements contained in this news release may be considered forward-looking statements within the meaning of Section 27A of the U.S. Securities Act of 1933, as amended, and Section 21E of the U.S. Securities Exchange Act of 1934, as amended. To the extent that any of the statements contained herein relating to QIAGEN's products, markets, strategy or operating results are forward-looking, such statements are based on current expectations that involve a number of uncertainties and risks. Such uncertainties and risks include, but are not limited to, risks associated with management of growth and international operations (including the effects of currency fluctuations and risks of dependency on logistics), variability of operating results, the commercial development of the applied testing markets, clinical research markets and proteomics markets, women's health/HPV testing markets, nucleic acid-based molecular diagnostics market, and genetic vaccination and gene therapy markets, changing relationships with customers, suppliers and strategic partners, competition, rapid or unexpected changes in technologies, fluctuations in demand for QIAGEN's, products (including fluctuations due to the level and timing of customers' funding, budgets, and other factors), our ability to obtain regulatory approval of our infectious disease panels, difficulties in successfully adapting QIAGEN's products to integrated solutions and producing such products, the ability of QIAGEN to identify and develop new products and to differentiate its products from competitors' products, market acceptance of QIAGEN's new products and the integration of acquired technologies and businesses. For further information, refer to the discussions in reports that QIAGEN has filed with, or furnished to, the U.S. Securities and Exchange Commission (SEC).



                              QIAGEN N.V.
              CONDENSED CONSOLIDATED STATEMENTS OF INCOME
                              (unaudited)

                                              Three months ended
                                                  December 31,
                                              2007            2006
                                          ------------    ------------
 Net sales                                $210,224,000    $125,891,000
 Cost of sales                              58,572,000      37,439,000
 Cost of sales - acquisition related         1,496,000         301,000
 Cost of sales - acquisition related
  intangible amortization                   11,359,000       1,789,000
                                          ------------    ------------
   Gross profit                            138,797,000      86,362,000
                                          ------------    ------------
 Operating Expenses:
  Research and development                  22,844,000      11,012,000
  Sales and marketing                       56,230,000      32,054,000
  General and administrative                23,172,000      12,075,000
  Purchased in-process research
   and development                                  --       1,900,000
  Acquisition, integration and
   related costs                             8,126,000       1,082,000
  Acquisition related intangible
   amortization                              3,354,000         674,000
  Relocation and restructuring costs            60,000         667,000
                                          ------------    ------------
 Total operating expenses                  113,786,000      59,464,000
                                          ------------    ------------

 Income from operations                     25,011,000      26,898,000
                                          ------------    ------------
 Other Income (Expense):
  Interest income                            3,669,000       5,559,000
  (Interest expense)                       (11,099,000)     (3,980,000)
  Other income (expense), net                2,574,000        (653,000)
                                          ------------    ------------
 Total other (expense) income               (4,856,000)        926,000
                                          ------------    ------------
 Income before provision for
  income taxes and minority interest        20,155,000      27,824,000
 Provision for income taxes                  5,099,000       8,377,000
 Minority interest income                       56,000              --
                                          ------------    ------------
 Net income                               $ 15,000,000    $ 19,447,000
                                          ============    ============
 Weighted average number
  of diluted common shares                 205,233,000     154,783,000

 Diluted net income per common share      $       0.07    $       0.13

 Diluted net income per common share
  excluding acquisition, integration
  and restructuring related charges
  as well as amortization of acquired
  IP and equity-based compensation
  (SFAS 123R)                             $       0.16    $       0.16


                              QIAGEN N.V.
              CONDENSED CONSOLIDATED STATEMENTS OF INCOME
                              (unaudited)
                                             Twelve months ended
                                                 December 31,
                                            2007             2006
                                       -------------    -------------
 Net sales                             $ 649,774,000    $ 465,778,000
 Cost of sales                           189,773,000      139,122,000
 Cost of sales - acquisition related       2,839,000        2,046,000
 Cost of sales - acquisition related
  intangible amortization                 23,615,000        6,135,000
                                       -------------    -------------
   Gross profit                          433,547,000      318,475,000
                                       -------------    -------------
 Operating Expenses:
  Research and development                64,935,000       41,560,000
  Sales and marketing                    164,690,000      115,942,000
  General and administrative              71,932,000       48,574,000
  Purchased in-process research
   and development                        25,900,000        2,200,000
  Acquisition, integration and
   related costs                          14,708,000        6,061,000
  Acquisition related intangible
   amortization                            7,711,000        2,085,000
  Relocation and restructuring costs         538,000        1,452,000
                                       -------------    -------------
 Total operating expenses                350,414,000      217,874,000
                                       -------------    -------------

 Income from operations                   83,133,000      100,601,000
                                       -------------    -------------
 Other Income (Expense):
  Interest income                         19,509,000       16,359,000
  (Interest expense)                     (31,455,000)     (11,918,000)
  Other income, net                        4,539,000        1,026,000
                                       -------------    -------------
 Total other (expense) income             (7,407,000)       5,467,000
                                       -------------    -------------
 Income before provision for
  income taxes and minority interest      75,726,000      106,068,000
 Provision for income taxes               25,555,000       35,529,000
 Minority interest income                     49,000               --
                                       -------------    -------------
  Net income                           $  50,122,000    $  70,539,000
                                       =============    =============
 Weighted average number of
  diluted common shares                  175,959,000      153,517,000

 Diluted net income per
  common share                         $        0.28    $        0.46

 Diluted net income per common
  share excluding acquisition,
  integration and restructuring
  related charges as well as
  amortization of acquired IP
  and equity-based compensation
  (SFAS 123R)                          $        0.63    $        0.56


                              QIAGEN N.V.
                 CONDENSED CONSOLIDATED BALANCE SHEETS
                              (unaudited)

                                         December 31,     December 31,
                                            2007             2006
                                       --------------   --------------
 Assets

 Current Assets:
  Cash and cash equivalents            $  347,320,000   $  430,357,000
  Marketable securities                     2,313,000       52,782,000
  Notes receivable                          5,139,000        4,247,000
  Accounts receivable, net                136,707,000       80,429,000
  Income taxes receivable                  10,696,000        2,901,000
  Inventories                              88,346,000       64,085,000
  Deferred income taxes                    23,732,000       18,627,000
  Prepaid expenses and other               33,693,000       29,763,000
                                       --------------   --------------
         Total current assets             647,946,000      683,191,000
                                       --------------   --------------
 Long-Term Assets:
  Property, plant and equipment, net      283,491,000      221,277,000
  Goodwill                              1,107,882,000      160,141,000
  Intangible assets, net                  639,107,000      118,492,000
  Deferred income taxes                    72,128,000        2,409,000
  Other assets                             24,620,000       26,502,000
                                       --------------   --------------
         Total long-term assets         2,127,228,000      528,821,000
                                       --------------   --------------
     Total assets                      $2,775,174,000   $1,212,012,000
                                       ==============   ==============

 Liabilities and Shareholders' Equity

 Current Liabilities:
  Short term loans                     $        4,000   $           --
  Current portion of long-term debt                --        6,599,000
  Current portion of capital lease
   obligations                              2,769,000          823,000
  Accounts payable                         40,379,000       23,806,000
  Accrued and other liabilities           104,220,000       66,197,000
  Income taxes payable                     13,456,000       13,746,000
  Deferred income taxes                     4,903,000        5,360,000
                                       --------------   --------------
         Total current liabilities        165,731,000      116,531,000
                                       --------------   --------------
 Long-Term Liabilities:
  Long-term debt, net of current
   portion                                950,000,000      489,592,000
  Capital lease obligations, net of
   current portion                         33,017,000       12,009,000
  Deferred income taxes                   225,893,000       21,705,000
  Other                                     8,405,000        6,010,000
                                       --------------   --------------
         Total long-term liabilities    1,217,315,000      529,316,000
                                       --------------   --------------
 Minority interest in consolidated
  subsidiaries                                553,000               --
                                       --------------   --------------
 Shareholders' Equity:
  Common shares, EUR .01 par value:
     Authorized -- 410,000,000 shares
     Issued and outstanding --
      195,335,076 shares in 2007 and
      150,167,540 shares in 2006            2,175,000        1,535,000
     Additional paid-in-capital           925,597,000      178,656,000
     Retained earnings                    388,779,000      344,739,000
     Accumulated other comprehensive
      income                               75,024,000       41,235,000
                                       --------------   --------------
         Total shareholders' equity     1,391,575,000      566,165,000
                                       --------------   --------------
     Total liabilities and
      shareholders' equity             $2,775,174,000   $1,212,012,000
                                       ==============   ==============


            

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