PLAINSBORO, N.J., April 21, 2008 (PRIME NEWSWIRE) -- Integra LifeSciences Holdings Corporation (Nasdaq:IART) announced today an in-kind donation of almost $3.0 million worth of neurosurgical medical devices to three CURE International hospitals located in the Dominican Republic, Uganda and Zambia. The hospital in the Dominican Republic serves as a referral center for children with orthopedic disabilities and deformities from all over the country. In Uganda, CURE treats children with conditions such as hydrocephalus, brain tumors and other conditions that require neurosurgical care. The hospital in Zambia cares for children with both orthopedic and neurosurgical conditions.

"We are very grateful for Integra's generous donation. CURE provides life-changing surgeries to children around the world and these much needed medical devices will provide many disabled children in the Dominican Republic, Uganda and Zambia the chance to have a normal life," said Dr. Scott Harrison, founder and CEO of CURE International.

Founded in 1996, U.S.-based CURE International has a 10-year history of transforming the lives of disabled children and their families in the developing world through medical and spiritual healing. CURE primarily treats children with curable orthopedic and neurosurgical conditions and brings hope and healing to these families' lives. CURE's goal is to help families and communities understand that they no longer have to let a disability determine the outcome of a child's life. In addition, CURE provides medical education and training to national medical professionals in countries where the organization has hospitals. To date, CURE has performed 46,000 surgeries and treated more than 650,000 patients. Visit www.cureinternational.org for more information.

"Integra is very pleased that our donation will help improve the lives of children in developing countries through much needed surgeries that they might not otherwise receive," said Integra's CEO, Stuart Essig.

Integra LifeSciences Holdings Corporation, a world leader in regenerative medicine, is dedicated to improving the quality of life for patients through the development, manufacturing, and marketing of cost-effective surgical implants and medical instruments. The company's products are used to treat millions of patients every year, primarily in neurosurgery, extremity reconstruction, orthopedics and general surgery. Integra's headquarters are in Plainsboro, New Jersey, and it has research and manufacturing facilities throughout the world. www.Integra-LS.com.

IART-G

Integra LifeSciences Holdings Corporation
John B. Henneman, III, Executive Vice President, Chief 
 Administrative Officer, Acting Chief Financial Officer
  (609) 936-2481
  jhenneman@Integra-LS.com 
Gianna Sabella, Public Relations Manager 
  (609) 936-2389
  gsabella@integra-LS.com