Tripep secures financing of ChronSeal

Tripep secures financing of ChronSeal

Tripep has renegotiated the agreement  with its Japanese partner Kringle Pharma
Inc. regarding the wound healing project ChronSeal®. According to the new
agreement Kringle Pharma takes on the economic responsibility, including
Tripep's internal costs, for the upcoming clinical study. Tripep reduces its
share in the project but retains a right to buy back an increased share in the
project. Furthermore Kringle Pharma will pay Tripep's accrued costs related to
the ChronSeal®-project amounting to approximately 500,000 US dollars. 

The value of the agreement corresponds to slightly more 19 million SEK in saved
costs for the ChronSeal project which is now taken over by Kringle Pharma. In
return Tripep's share in the project will decrease from present 60%, but with a
right to buy back into the project with up to 50% before the 31st of March 2009
and up to 40% until the 30th of June 2010. Should Tripep chose not to buy back
sharing in the project Tripep will still retain 10% of all revenue from the
project.

 Tripep can also report that approval from the Norwegian Medicines Agency has
been obtained for conducting the clinical trial on ChronSeal®. The trial is a
placebo-controlled multicenter study on chronic leg wounds. Approval from the
ethics committees in Norway and Sweden has already been obtained. 

”The market for chronic leg ulcers is estimated to SEK  36 billion and the
growth rate is high. Really efficient treatments do not exist whilst HGF has
shown very encouraging results in a clinical pilot study. After having received
the approval from the Norwegian Medicines Agency to start the phase II study and
having renegotiated the agreement  with Kringle Pharma, the ChronSeal project
can continue as planned. At the same time Tripep keeps the right to
substantially increase its share in the project before the end of quarter I 2009
respectively quarter II 2010. Taken together it gives us and our shareholders a
possibility to  get a proof -of-concept for the new formulation of ChronSeal®
before we decide upon further investments in the project”, says Tripep's CEO Jan
Nilsson.

For more information, please contact:
Jan Nilsson, CEO, Tripep AB			
Tel: +46 8 449 84 80, Mobile phone: +46 70 466 31 63             		
E-mail: jan.nilsson@tripep.se

Anders Vahlne, Head of Research, Tripep AB
Tel: +46 8 5858 1313, Mobile phone: +46 709 28 05 28
E-mail: anders.vahlne@ki.se





About Tripep
Tripep develops drugs against chronic disease based on proprietary and other
parties' patented and patent pending technologies. Tripep is focusing on the
following research projects; wound healing therapy ChronSeal® and a therapeutic
vaccine against Hepatitis C, named ChronVac-C®, plus the RAS® technology
platform. The Tripep share is admitted to trade on First North. Remium AB is
Certified Adviser for Tripep AB.  For more information, please refer to the
company's website: www.tripep.se.

About ChronSeal® 
ChronSeal® is a HGF-based (Hepatocyte Growth Factor) treatment for chronic leg
wounds, a rapidly increasing problem among the elderly population of the Western
World. In cooperation with Tripep's partners Kringle Pharma, Inc. and Zelmic AB,
a new formulation has been developed that enables the use of ChronSeal® without
it being combined with antibiotics. The new formulation allows for controllable
release of HGF, thus avoiding antibiotic resistance, another rapidly growing
problem. An application for a patent pertaining to an antibiotic-free
formulation of ChronSeal® was filed in the US in January 2008. 

More than four million people in the US and Europe are currently suffering from
chronic leg wounds which corresponds to a market value of approximately SEK 36
billion. Accordingly, the medical need is considerable and the growth rate is
high, factors that are expected to provide ChronSeal® with substantial
commercial potential.

In the event of any discrepancy between the Swedish and English versions of this
press release, the Swedish version will take precedence.