Novo Nordisk A/S - Share repurchase programme On 15 August 2008 Novo Nordisk initiated its share repurchase programme in accordance with the provisions of the European Commission's regulation no 2273/2003 of 22 December 2003, also referred to as the Safe Harbour rules. Under the programme Novo Nordisk will repurchase B shares for an amount of up to DKK 1.7 billion in the period from 15 August 2008 to 19 December 2008. Since the announcement as of 3 November 2008, the following transactions have been made under the programme: Number of Average Transaction shares purchase price value, DKK Accumulated, last announcement 3,088,500 866,659,744 3 November 2008 58,000 307.0700 17,810,060 4 November 2008 50,000 321.4400 16,072,000 5 November 2008 80,000 316.0400 25,283,200 6 November 2008 50,000 310.3600 15,518,000 7 November 2008 50,000 305.6100 15,280,500 Accumulated under the programme 3,376,500 956,623,504 Transactions related to Novo Nordisk's incentive programmes have resulted in a net sale by Novo Nordisk of 93,950 B-shares in the period from 3 November 2008 to 7 November 2008. The shares in these transactions were not part of the Safe Harbour repurchase programme. With the transactions stated above, Novo Nordisk owns a total of 24,426,590 treasury shares, corresponding to 3.9% of the share capital. The total amount of shares in the company is 634,000,000 including treasury shares. Novo Nordisk is a healthcare company and a world leader in diabetes care. In addition, Novo Nordisk has a leading position within areas such as haemostasis management, growth hormone therapy and hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical products and services that make a significant difference to patients, the medical profession and society. With headquarters in Denmark, Novo Nordisk employs approximately 26,550 employees in 80 countries, and markets its products in 179 countries. Novo Nordisk's B shares are listed on the stock exchanges in Copenhagen and London. Its ADRs are listed on the New York Stock Exchange under the symbol 'NVO'. For more information, visit novonordisk.com. Further information: Media: Investors: Elin K Hansen Mads Veggerby Lausten Tel: (+45) 4442 3450 Tel: (+45) 4443 7919 ekh@novonordisk.com mlau@novonordisk.com Hans Rommer Tel: (+45) 4442 4765 hrmm@novonordisk.com In North America: Sean Clements Tel: (+1) 609 514 8316 secl@novonordisk.com Company Announcement no 74 / 2008