BIOTIE THERAPIES CORP. STOCK EXCHANGE RELEASE February 3, 2009, at 2 p.m. Notification according to Chapter 2, Section 10 of the Finnish Securities Market Act Biotie Therapies Corp. ("Company") has gained knowledge of the notifications regarding the following changes in holdings in accordance with Chapter 2, Section 9 of the Finnish Securities Markets Act. Pequot Healthcare Fund, L.P., Pequot Healthcare Offshore Fund, Inc., Premium Series PCC Limited - Cell 32, Pequot Diversified Master Fund, Ltd., Pequot Healthcare Institutional Fund, L.P. and Pequot Healthcare Emerging Markets Master Fund, Ltd. have notified that as a result of share transactions carried out on 30 January, 2009, the aggregate holdings of these shareholders have decreased from above 15 % to 13.66 %. Moreover, as a result of these share transactions carried out on 30 January 2009, the holdings of Pequot Healthcare Fund, L.P. have decreased from above 5 % to 4.69 %. The changes in holdings in accordance with Chapter 2, Section 9 of the Finnish Securities Markets Act of which the Company has gained knowledge are described below. Name of the shareholder Shares Shares % of shares prior to the after the after the transactions transactions transactions Pequot Healthcare Fund, L.P. 7,244,966 6,767,801 4.69 Pequot Healthcare Offshore 6,387,783 5,321,783 3.69 Fund, Inc. Premium Series PCC 2,111,387 1,741,590 1.21 Limited - Cell 32 Pequot Diversified Master 1,314,100 1,084,000 0.75 Fund, Ltd. Pequot Healthcare 2,254,305 1,859,906 1.29 Institutional Fund, L.P. Healthcare Emerging 3,571,637 2,946,170 2.04 Markets Fund, Ltd. SUBTOTAL 22,884,178 19,721,250 13.66 The registered number of shares in Biotie Therapies Corp. is 144 320 560 and the number of voting rights attached to the shares amounts to 144 320 560. Turku, February 3, 2009 Timo Veromaa President and CEO For further information, please contact: Timo Veromaa, President and CEO, Biotie Therapies Corp. tel. +358 2 274 8900, e-mail: timo.veromaa@biotie.com www.biotie.com DISTRIBUTION NASDAQ OMX Helsinki Ltd Main Media
Notification according to Chapter 2, Section 10 of the Finnish Securities Market Act
| Source: Biotie Therapies