TopoTarget A/S Symbion Fruebjergvej 3 DK 2100 Copenhagen Denmark Tel: +45 39 17 83 92 Fax: +45 39 17 94 92 CVR-nr: 25695771 www.topotarget.com Pursuant to the Danish Securities Trading Act and Executive Order on Assessment, Notification and Disclosure of Major Holdings etc. (Executive Order No. 1225 of 22 October 2007), TopoTarget A/S hereby provides notice that the company has today received a major shareholder notification from PKA A/S, informing that PKA A/S' shareholding in TopoTarget A/S now amounts to 4.73 % of TopoTarget A/S' share capital. TopoTarget A/S For further information, please contact: Ulla Hald Buhl Telephone +45 39 17 83 92 Director IR & Communications Mobile +45 21 70 10 49