BRISBANE, Calif. and PARIS, May 18, 2009 (GLOBE NEWSWIRE) -- Results from a Phase II clinical trial of BiPar Sciences' -- a wholly-owned sanofi-aventis subsidiary -- lead PARP inhibitor, BSI-201, will be a featured oral plenary presentation at the 45th annual meeting of the American Society of Clinical Oncology (ASCO), Orlando, FL.
The study (Abstract #3 in the ASCO Proceedings 1) is a randomized Phase II trial of BSI-201, a poly (ADP-ribose) polymerase-1(PARP1) inhibitor, in combination with gemcitabine/carboplatin in patients with metastatic triple negative breast cancer (TNBC). Results will be highlighted through the following ASCO venues:
ASCO Oral Plenary Session Sunday, May 31 from 1:00 - 4:00 p.m. ET Science of PARP and PARP inhibition introduction is scheduled for 2:45 p.m. ET BSI-201 Phase 2 data presentation is scheduled for 3:00-3:15 p.m. ET Presented by lead investigator Dr. Joyce O'Shaughnessy Level 2, West Hall D2 ASCO Press Conference Sunday, May 31 at 8:30 a.m. ET Woman's Cancers ASCO Press Briefing Best of ASCO 2009 educational program intended to highlight the most relevant, cutting-edge science in oncology today. Sessions will be held in Los Angeles and Atlanta in the United States and in several countries across the globe in the months following the ASCO annual meeting.
ASCO is the world's leading professional organization representing physicians who care for people with cancer. Approximately 30,000 cancer specialists from around the world are expected to gather at ASCO to discuss the latest advances in cancer care, treatment, prevention and survivorship. More than 4,000 abstracts have been accepted to the meeting. For information on abstract embargo schedules and other ASCO information and resources, visit www.asco.org/presscenter.
Among other investigational PARP inhibitors in the industry, BSI-201 is the furthest along in clinical development in metastatic TNBC. BSI-201 is currently being evaluated for its potential to enhance the effect of chemotherapy-induced DNA damage. The clinical development of BSI-201 is supported by well documented safety profile based on studies of more than 200 patients.
Sanofi-aventis, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to help improve the lives of patients. Sanofi-aventis is listed in Paris (EURONEXT:SAN) and in New York (NYSE:SNY). For more information, visit: www.sanofi-aventis.us or www.sanofi-aventis.com.
About BiPar Sciences
BiPar Sciences is a biopharmaceutical organization pioneering novel tumor-selective therapies being investigated in settings of urgent unmet need for cancer patients. BiPar Sciences, located in Brisbane, California, is a wholly-owned sanofi-aventis subsidiary. For more information, please visit www.biparsciences.com.
BiPar Sciences Stephan Herrera 1-415-794-4005