Report pursuant to the Danish Securities Trading Act, Section 28a


TopoTarget A/S
Symbion
Fruebjergvej 3
DK 2100 Copenhagen Ø
Denmark
Tel: +45 39 17 83 92
Fax: +45 39 17 94 92
CVR-nr: 25695771
www.topotarget.com

Copenhagen - 2 July, 2009 - Pursuant to the Danish Securities Trading Act,
Section 28a TopoTarget A/S (OMX: TOPO) is obliged to report on transactions by
members of its board of directors, senior management and their related parties
in shares issued by TopoTarget A/S and related securities. 


Name	             Buhl Krone Holding ApS, a company wholly-owned by CEO
Reason	             of TopoTarget A/S, Peter Buhl Jensen
Issuer 	             TopoTarget A/S
ISIN code            DK0060003556
Transaction	     Acquisition (subscription) of TopoTarget shares
Trade date	     29 June 2009 
Market	             NASDAQ OMX Copenhagen A/S
Number	             239.222
Market value in DKK  478.444

Name	             Håkan Åström 
Reason	             Chairman of TopoTarget A/S
Issuer	             TopoTarget A/S
ISIN code	     DK0060003556
Transaction	     Acquisition (subscription) of TopoTarget shares
Trade date	     29 June 2009
Market	             NASDAQ OMX Copenhagen A/S
Number	             317.000
Market value in DKK  634.000


TopoTarget A/S

For further information, please contact:

Peter Buhl Jensen	    Telephone	+45 39 17 83 92
CEO		        Mobile	    +45 21 60 89 22
	
Background information

About TopoTarget 
TopoTarget (OMX: TOPO) is an international biotech company headquartered in
Denmark, dedicated to finding ''Answers for Cancer'' and developing improved
cancer therapies. The company was founded and is run by clinical cancer
specialists and combines years of hands-on clinical experience with in-depth
understanding of the molecular mechanisms of cancer. 
TopoTarget has a broad clinical pipeline but is currently focusing on the
development of belinostat, which has shown proof of concept as monotherapy in
treating haematological malignancies and positive results in solid tumours
where it can be used in combination with full doses of chemotherapy, and is in
phase III in PTCL. TopoTarget's expertise in translational research is
utilizing its highly predictive in vivo and in vitro cancer models. TopoTarget
is directing its efforts on key cancer targets including HDACi, NAD+, mTOR,
FasLigand and topoisomerase II inhibitors. The company's first marketed product
Savene®/Totect® was approved by EMEA in 2006 and the FDA in 2007 and is
marketed by TopoTarget's own sales force in Europe and the US. For more
information, please refer to www.topotarget.com.

Attachments

announcement no  32-09 report pursuant to the danish securities trading act section 28a.pdf