TopoTarget A/S Symbion Fruebjergvej 3 DK 2100 Copenhagen Denmark Tel: +45 39 17 83 92 Fax: +45 39 17 94 92 CVR-nr: 25695771 www.topotarget.com Copenhagen - 3 January, 2010 - TopoTarget A/S (NASDAQ OMX: TOPO.CO) hereby announces that the Company has today received a notification from Försäkringsaktiebolaget Avanza Pension (organization number 516401-6775, that Avanza Pension's holdings of shares and voting rights have now exceeded 5% of TopoTarget's total share capital and total number of voting rights. TopoTarget A/S For further information, please contact: Peter Buhl Jensen Telephone +45 39 17 83 92 CEO Mobile +45 21 60 89 22