Company Announcement no. 4/2010 To: NASDAQ OMX Copenhagen A/S Hørsholm, Denmark, March 30, 2010 LIFECYCLE PHARMA A/S SUMMONS ANNUAL GENERAL MEETING LifeCycle Pharma A/S (OMX: LCP) (the “Company”) will hold its Annual General Meeting on Wednesday, April 21, 2010 at 9:00 am at the Company's office at Kogle Allé 4, 2970 Hørsholm, Denmark. Agenda: 1. Report of the Board of Directors on the Company's activities during the year. 2. Presentation of the audited Annual Report for approval. The Board of Directors proposes that the audited Annual Report is approved. 3. Decision as to the settlement of loss according to the adopted Annual Report. The Board of Directors proposes that the year's net loss of DKK 271.0 million be carried forward by transfer to accumulated deficit. 4. Approval of the Fee to the Board of Directors. 5. Election of members of the Board of Directors. Under Article 16 of the Articles of Association, the members of the Board of Directors are elected for one year at a time. The following members of the Board of Directors are standing for re-election: Kurt Anker Nielsen, Thomas Dyrberg Gérard Soula, Jean Deleage, Anders Götzsche and Paul Edick. The Board of Directors proposes that Mette Kirstine Agger is elected as a new member of the Board of Directors. 6. Election of Auditor. The Board of Directors proposes re-election of PricewaterhouseCoopers, Statsautoriseret Revisionsaktieselskab, as the Company's elected auditor. 7. Any motions from the Board of Directors and/or shareholders. The Board of Directors has submitted the following proposals: 7.1. Amendments to the Articles of Association: (A) Amendments to the Articles of Association due to the changes in the new Danish Companies Act. (i) Mandatory changes, being: terminology, manner and length of convening notice, deadline for motions from the shareholders, new minority of shareholders' right to demand that an extraordinary general meeting is held, introduction of the concept of a registration date, new deadline for requesting attendance, obligation to make documents and information available 3 weeks before general meetings. (ii) Optional changes due to the New Companies Act, being: deletion of the Company's registered office, new section dealing with the shareholders' right to vote per mail, change to the rules concerning proxies and advisors. (B) Other proposed amendments to the Articles of Association, being: (i) Change the Share Registrar to Computershare A/S (due to name change) and inclusion of a generic reference to “central securities depository”. (ii) Delete “discharge is granted to the Board of Directors and the Management” and “election of alternates, if any” from the agenda for the Annual General Meeting. (iii) Amendment of Article 8 to authorize the Board of Directors to issue up to 3,000,000 warrants. (iv) Adoption of new Article 23 which allows the company to use electronic communication with its shareholders instead of ordinary mail. (v) The board of directors proposes that English is formally adopted as the corporate language (new Article 24). 7.2. Authorization for the Company to acquire own shares. 7.3. Authority for the chairman of the Annual General Meeting. Details concerning the proposals made by the Board of Directors: Re Agenda Item 4 Under this agenda item, the Board of Directors proposes that the actual Fee for the previous year as well as the level for the election period 2010-2011 is approved. The Fee to the Board of Directors for 2009 is disclosed on page 32 in the Annual Report for 2009. The Board of Directors proposes the same structure and level for the election period 2010-2011. As the Company will have an additional member, it is expected that the remuneration level for the Board of Directors as a group will increase by the fee to an additional member of the Board of Directors. Re Agenda Item 5 The Board of Directors proposes that the following current members of the Board of Directors being Dr. Thomas Dyrberg, Kurt Anker Nielsen, Dr. Jean Deleage, Dr. Gérard Soula, Paul Edick and Anders Götzsche are re-elected until the Annual General Meeting to be held in 2011. Information concerning each member can be found in the Company's Annual Report for 2009 and on the Company's homepage www.lcpharma.com. The Board of Directors proposes that Mrs. Mette Kirstine Agger is elected member of the Board of Directors for a one-year period. About Mette Kirstine Agger: Mette Kirstine Agger is an Executive Director and Head of LFI Life Science Investments A/S. She joined LFI A/S, a company fully owned by the Lundbeck Foundation, September 1st 2009. Prior to this, Mette Kirstine Agger was CEO of 7TM Pharma A/S, which she co-founded late 2000, and from 1996 - 200 she was part of the management team at NeuroSearch A/S, responsible for business development and licensing. Prior to this she worked with business development and as a patent agent. Mette Kirstine Agger is a member of the Board of Directors at Harboe Breweries A/S and Statens Serum Institute and is Chairman of the Board of Directors at Klifo A/S. Mette Kirstine Agger has a Master of Science in biology from Copenhagen University and an MBA from Henley, UK. Mette Kirstine Agger will be regarded a dependant Board Member, based on the definition in the Corporate Governance Recommendation (2008) due to her employment with LFI A/S. Mette Kirstine Agger's special competences, important for her capacity as a Board Member, are her extensive biotech industry experience and network together with her extensive business development experience and knowledge of intellectual properties within the pharmaceutical sector. Mette Kirstine Agger is a Danish citizen, born in 1964. Re Agenda Item 7.1. Amendments to the Articles of Association As a result of the new Danish Companies Act, the Board of Directors proposes a number of changes to the Company's Articles of Association. The changes that are required as a result of the new Companies Act, are proposed as one single proposal under agenda item no. 7.1.(A)(i), while the other changes that relate to, but are not mandatory to make, are proposed as one single proposal under agenda item no. 7.1 (A)(ii). Other proposed changes to the Articles of Association are made individually under agenda item no. 7.1.(B). Re Agenda Item 7.1. (A) (i) (mandatory amendments) (1) In Articles 10 and 11 the word “share register” is proposed changed to “Register of Owners”. (2) In Article 11(2) it is proposed that the notice period for convening general meetings be changed to a minimum of three weeks and a maximum of five weeks and it is added that the convening notice shall also be made public via the Company's website. The changes to Article 11(2) are the following: “General Meetings shall be convened with a notice of minimum 8 days 3 weeks and maximum 4 5 weeks by publication in minimum 1 national newspaper and, by announcement on the Danish Commerce and Companies Agency's IT information system and on the Company's webpage. A convening notice shall, furthermore, be forwarded in writing by ordinary mail to all shareholders recorded in the Share Register of Owners who have requested such notification. The convening notice shall contain the agenda for the General Meeting. If the agenda contains proposals, the adoption of which require a qualified majority, the convening notice shall contain a specification of such proposals and their material contents.” (3) In Article 12(1) the deadline for motions from the shareholders for the annual general meeting shall be changed so that the shareholders must make a motion in writing no later than 6 weeks before the annual general meeting and description of the Board of Directors' ability to accept motions received after the deadline. (4) In Article 12(2) the shareholders' right to demand that an extraordinary general meeting is held is changed, so that this may be requested by shareholders who represent 1/20 of the share capital (rather than 1/10). “14 days” in the last sentence is changed to “2 weeks”. Article 12 is proposed to be changed as follows: “Article 12 The Annual General Meeting shall be held within 4 months after the expiry of the financial year. Motions from shareholders shall, in order to be considered at the Annual General Meeting, be filed in writing with the Board of Directors at the latest 4 6 weeks before the Annual General Meeting unless the Board of Directors resolves that motions filed later were filed in such timely fashion that the motion can be included on the agenda. Extraordinary General Meetings shall be held according to resolutions by the General Meeting or the Board of Directors or upon written request to the Board of Directors from one of the elected auditors, and if a request is presented by shareholders representing in aggregate at least 1/10 1/20 of the share capital. A request from shareholders representing at least 1/10 1/20 of the share capital shall specify the motion to be considered by the General Meeting. The General Meeting shall in this case be convened within 2 weeks 14 days from the date the motion has been presented to the Board of Directors.” (5) Introduction of the concept of a registration date so that the shareholders' right to participate and vote at the General Meeting is determined on the basis of the ownership, which has been recorded or filed for recording in the Company's Register of Owners no later than 1 week before the General Meeting. Change to the deadline for the shareholders' request for admission card to attend the General Meeting to three days rather than five days. Article 14(2) is proposed to be replaced in its entirety as follows: “Any shareholder is entitled to attend General Meetings, vote and exercise other shareholder rights provided that the shareholder, not later than 5 days prior to the General Meeting, has requested the Company to issue an admission card. Admission cards will be issued to shareholders who are recorded in the Company's Share Register or against presentation of a deposit transcript from VP Securities Services or the relevant bank. The transcript must not be dated more than 8 days before the date of presentation.” A shareholder's right to attend General Meetings and to vote at General Meetings is determined on the basis of the shares that the shareholder owns on the registration date. The registration date shall be 1 week before the General Meeting is held. The shares which the individual shareholder owns are calculated on the registration date on the basis of the registration of ownership in the Register of Owners as well as notifications concerning ownership, which the Company has received with a view to update the ownership in the Register of Owners. In addition, any shareholder who is entitled to attend a General Meeting and who wishes to attend must have requested an admission card from the Company no later than 3 days in advance of the General Meeting.” (6) The requirements contained in Article 13(1) to make documents available before the General Meeting are expanded so that they now comply with section 98 cf. section 99 of the Companies Act with respect to contents and timelines. Article 13(1) is proposed to be changed as follows: “At the latest 8 days before a General Meeting, the agenda and the complete proposals which shall be considered by the General Meeting, and in respect to the Annual General Meeting also the audited annual report and the annual statement from the Board of Directors and management, shall be available for inspection by the shareholders at the Company's office and shall be forwarded to all shareholders recorded in the Share Register who has requested this. “At the latest 3 weeks before a General Meeting (inclusive of the day of the General Meeting), the Company shall make the following information and documents available on the Company's webpage: the convening notice, the total number of shares and voting rights on the date of the convening, the documents that shall be presented at the General Meeting, the agenda and the complete proposals as well as the forms to be used for proxy voting or voting by letter unless these are sent directly to the shareholders. If said forms cannot be made available for technical reasons on the internet, the Company shall on its webpage inform how the form can be obtained in hardcopy; in which case the Company shall send the forms to any shareholders who requests this.” Re Agenda Item 7.1 (A) (ii) (voluntary amendments) (1) The Board of Directors proposes to delete Article 2 regarding the Company's registered office as this is no longer required under the Companies Act. (2) The Board of Directors proposes to include the following section dealing with the shareholders' right to vote per mail as a new last section of Article 14: “Shareholders who are entitled to vote cf. article 14 (2) may vote by letter. Votes made by letter must be received by the Company no later than 12.00 noon on the business day before the General Meeting.” (3) The Board of Directors proposes to change the rules concerning proxies and advisors so that only proxies to the Company's management or Board of Directors is time-limited to 12 months, and that these may in addition only be given to a specific General Meeting with an agenda, which is known in advance. Inclusion of a description that a proxy-holder may attend together with an advisor. The current Article 14(3) is proposed to be replaced by the following: “Any shareholder is entitled to attend in person or be represented by proxy and may attend together with an advisor. It is a condition that the representative presents a written power of attorney, which is dated. A power of attorney cannot be given for a period in excess of 1 year Any shareholder is entitled to attend in person or be represented by proxy, and both the shareholder and the proxyholder may attend together with an advisor. A shareholder may vote by proxy. It is a condition that the representative presents a written power of attorney, which is dated. A power of attorney cannot be given to the company's Board of Directors or management for a period in excess of 1 year and must be given to a specific General Meeting with an agenda known in advance.” Re Agenda Item 7.1 (B) (i) The Share Registrar has changed his name from “I-nvestor A/S” to “Computershare A/S”. It is proposed to adopt a generic reference to “central securities depository” to replace the reference to “VP Securities Services”, in order to avoid subsequent amendments to the Articles of Association due to name change or change in central securities depository. The revised Article 10 is set forth below: “Article 10 The Company's shares shall be bearer shares, but may be recorded on name in the Company's Share Register of Owners. The Company's Share Register of Owners shall be kept and maintained by I-nvestor Computershare A/S, Kongevejen 418, DK-2840 Holte. The Company's shares are issued through VP Securities Services a central securities depository and dividends are in accordance with the rules applicable from time to time for VP Securities Services such central securities depository paid by way of transfer to accounts designated by the shareholders. Re Agenda Item 7.1 (B) (ii) The Board of Directors proposes to amend the standard agenda for the Annual General Meeting so (i) in Article 13(2) “granting of discharge to the Board of Directors and management“, (ii) in Article 13(5) “and election of alternates, if any” are deleted in line with corporate governance standards. The revised Article 13(2) and Article 13(5) are set forth below: “Article 13 [. . .] The agenda of the Annual General Meeting shall include: 1. Report on the Company's activities during the past year. 2. Presentation of audited annual report with auditor's statement for approval and granting of discharge to the Board of Directors and management. 3. Resolution on application of profits or covering of losses as per the adopted annual report. 4. Approval of Fee to the Board of Directors. 5. Election of board members and alternates, if any. 6. Election of auditor. 7. Any motions from the Board of Directors and/or shareholders.” Re Agenda Item 7.1 (B) (iii) Under the existing authorization for the Board of Directors to issue warrants in Article 8 of the Articles of Association, 1,018,000 warrants remain unissued. The Board of Directors proposes to amend Article 8 to authorize the issue of additional warrants - without pre-emption rights for the existing shareholders - that give the right to subscribe up to a total of nominally DKK 3,000,000 shares in the Company to employees, executive directors, board members, consultants and advisors to the Company and its subsidiaries and to implement the corresponding capital increases. Also, the Board of Directors proposes to prolong the authorization to expire 5 years after this year's Annual General Meeting. The Board of Directors believes that it is necessary for the Company, in order for it to be able to retain and attract a sufficient number of qualified employees, board members and consultants, to be able to offer warrants as part of the employment or affiliation with the Company etc. The revised Article 8 is set forth below: “Article 8 The Board of Directors is until 20 April 2010 20 April 2015 authorised, at one or more times, to issue up to 1,018,000 3,000,000 warrants, each conferring a right to subscribe for 1 share of nominal DKK 1 in the Company, and to implement the corresponding increase of the share capital. The warrants can be issued to employees, executive directors, board members, consultants and advisors to the Company and its subsidiaries without pre-emptive subscription rights for the Company's shareholders. The exercise price for warrants, which are issued pursuant to the authorisation, shall at a minimum correspond to the market price of the Company's shares on the date of issuance of the warrants. The other terms for the warrants issued pursuant to this authorisation, including payment for the warrants, duration, exercise periods, vesting periods, adjustments as a result of corporate changes etc. shall be determined by the Board of Directors. The Board of Directors is according to the Companies Act section 40 b, subsection 3 entitled to make such amendments to the Articles of Association, which are connected with the issuance of warrants comprised by this clause or the exercise thereof.” Re Agenda Item 7.1 (B) (iv) In order to reduce the Company's costs when communicating with its shareholders and in order to facilitate shareholder communication, it is suggested that the Company may in the future use electronic communication with its shareholders instead of ordinary mail. The right to use electronic communication is suggested to be incorporated in a new article 23 of the Articles of Association with the following wording: “ELECTRONIC COMMUNICATION Article 23 The Company may make use of electronic document exchange and electronic mail (electronic communication) in its communications with shareholders cf. section 92 of the Danish Companies Act. The Company may at any time elect to communicate by ordinary mail but is not obligated to do so. All announcements and documents that pursuant to the Company's Articles of Association, the Danish Companies Act as well as stock exchange legislation and regulations must be exchanged between the Company and the shareholders, including, by example, notices to convene annual or extraordinary general meetings along with agendas and full wordings of proposed resolutions, proxies, interim reports, annual reports, stock exchange announcements, financial calendar and prospectuses, as well as general information from the Company to the shareholders may be sent as an attached file by e-mail or by including in an e-mail exact information as to where the document may be downloaded (a link). The Company shall request its name-registered shareholders to forward an electronic address which may be used for electronic notices. It is the responsibility of the individual shareholder to ensure that the Company is informed of the correct address. Information about system requirements and about the procedure for electronic communications can be found on the Company's website www.lcpharma.com.” Re Agenda Item 7.1 (B) (v) The Board of Directors proposes that English is formally adopted as the corporate language, since the board and employees are comprised by many different nationalities. The Board proposes that the following is adopted as a new Article 24 of the Articles of Association: “LANGUAGE Article 24 The corporate language shall be English.” Re Agenda Item 7.2 The Board of Directors proposes that the Board of Directors be authorized until the next Annual General Meeting to arrange for the Company to acquire own shares up to a total nominal value of 10% of the Company's nominal share capital. The purchase price of such shares may not differ by more than 10% from the price quoted on NASDAQ OMX Copenhagen at the time of purchase. The Board of Directors regards it as good corporate governance that the authorisation is limited in terms of number of shares, and that it shall be approved by the shareholder once annually. Re Agenda Item 7.3 It is proposed that the chairman of the Annual General Meeting with right of substitution, be authorized to register the resolutions passed by the General Meeting to the Danish Commerce and Companies Agency and to make such alterations as the Agency may require for registration or approval. -oo0oo- The adoption of the proposals to amend the Articles of Association contained under Items 7.1(A)(ii) and 7.1(B) of the agenda requires a majority in favour of the proposed resolution of at least two thirds of both the votes cast and of the voting share capital represented at the General Meeting. The adoption of the proposals to amend the Articles of Association contained under Item 7.1(A)(i) of the agenda only requiresthat one shareholder votes in favour. The other proposals are adopted by a majority of the votes cast. The Company's share capital is currently nominal DKK 56,567,810 consisting of 56,567,810 shares of nominal DKK 1 each. At the Annual General Meeting, each share of nominal DKK 1 carries one vote. Shareholders exercise their financial rights through their own custodian bank. No later than 21 days before the Annual General Meeting, the convening notice with the agenda and the complete proposals as well as all documents that shall be presented at the General Meeting including the annual report and the annual statement from the Board of Directors and management will be made available to the Company's shareholders at the Company's offices at Kogle Allé 4, DK-2970 Hørsholm, Denmark. The documents together with the forms to be used for proxy voting are also available on the Company's website, www.lcpharma.com, and will be forwarded to all shareholders recorded in the Share Register who have requested such notification. Admission card: Any shareholder is entitled to attend the Annual General Meeting after having submitted a request for an admission card no later than Friday April 16, 2010 at 4:00 pm. Admission cards may be requested by contacting Computershare A/S, Kongevejen 418, DK-2840 Holte, Tel.: +45 46 09 99, Fax: +45 46 09 98. Alternatively, via www.lcpharma.com. Shareholders who do not expect to be able to participate in the Annual General Meeting may grant proxy to the Board of Directors or to a person appointed by the shareholder. Any shareholder, to whom admission card already has been issued, but who is prevented from attending the Annual General Meeting, is kindly asked to notify the Company - preferably before Friday April 16, 2010. For more information, please contact: LifeCycle Pharma A/S William J. Polvino Peter Schøtt Knudsen President and CEO Head of Investor Relations Phone: + 45 70 33 33 00 Phone: + 45 20 55 38 17 Email: WJP@lcpharma.com Email: PSK@lcpharma.com For further information, please also visit www.lcpharma.com.