Topotarget announces interim report for 1 January to 30 September 2010


Topotarget A/S
Symbion
Fruebjergvej 3
DK-2100 Copenhagen
Denmark
Tel: +45 39 17 83 92
Fax: +45 39 17 94 92
CVR-nr: 25695771
www.topotarget.com




Copenhagen, Denmark - 18 November 2010 - Topotarget A/S (NASDAQ OMX: TOPO)
announced today the company's interim report for the period 1 January to 30
September 2010. 



•	The cash and cash equivalents position as at the end of Q3 2010 was DKK 225.4
million compared with DKK 262.1 million at the end of Q2 2010. This is a cash
movement of DKK 36.7 million.  Topotarget confirms its guidance for cash and
cash equivalents of DKK 195 million to DKK 215 million as at 31 December 2010 
 
•	Topotarget recognised  revenues of DKK 95.9 million (281% increase) during
the period compared with DKK 34.1 million in the same period last year 

•	Operating expenses for the nine months period ended 30 September 2010 were
DKK 113.5 million  compared to DKK 115.4 million for the same period 2009 

•	Operating profit for the nine months period ended 30 September 2010 was DKK
14.9 million compared to a loss of DKK 81.3 million for the same period 2009 

•	Topotarget confirms its financial guidance of a pre-tax profit for the 2010
financial year of approximately DKK 0 million to DKK 20 million 

The whole report is attached as a PDF-file or can be found on Topotarget's
website. 


Topotarget A/S

For further information, please contact:

Francois Martelet, CEO: Direct: +45 39 17 83 43; Mobile: +45 51 32 83 41
Anders Vadsholt, CFO: Direct: +45 39 17 83 45; Mobile: +45 28 98 90 55


Background information

About Topotarget
Topotarget (NASDAQ OMX: TOPO) is a Scandinavian based international biotech
company headquartered in Denmark, dedicated to improve cancer therapies. In
collaboration with Spectrum Pharmaceuticals, Inc. Topotarget currently focuses
on the development in pivotal studies of its lead drug candidate, belinostat,
which has demonstrated a clear anti neoplastic effect in both hematological
malignancies and solid tumors. Belinostat can be used in combination with full
doses of chemotherapy, and is currently in a pivotal trial within PTCL
(peripheral T-cell lymphoma) and phase II in cancer of unknown primary (CUP).
Topotarget's key cancer drug targets are HDAC, NAD+, mTOR, Fas ligand and
topoisomerase II. Totect® is a product on the market developed from
Topotarget's drug discovery technology. Totect® is marketed by the company's
own sales specialists in the US. The European rights to Savene® were divested
in March 2010 as a consequence of the focus to develop and commercialise
belinostat. For more information, please refer to www.topotarget.com. 


Topotarget Safe Harbour Statement
This announcement may contain forward-looking statements, including statements
about our expectations of the progression of our preclinical and clinical
pipeline including the timing for commencement and completion of clinical
trials and with respect to cash burn guidance. Such statements are based on
management's current expectations and are subject to a number of risks and
uncertainties that could cause actual results to differ materially from those
described in the forward-looking statements. Topotarget cautions investors that
there can be no assurance that actual results or business conditions will not
differ materially from those projected or suggested in such forward-looking
statements as a result of various factors, including, but not limited to, the
following: The risk that any one or more of the drug development programs of
Topotarget will not proceed as planned for technical, scientific or commercial
reasons or due to patient enrolment issues or based on new information from
non-clinical or clinical studies or from other sources; the success of
competing products and technologies; technological uncertainty and product
development risks;  uncertainty of additional funding; Topotarget's history of
incurring losses and the uncertainty of achieving profitability; Topotarget's
stage of development as a biopharmaceutical company; government regulation;
patent infringement claims against Topotarget's products, processes and
technologies; the ability to protect Topotarget's patents and proprietary
rights; uncertainties relating to commercialization rights; and product
liability exposure; We disclaim any intention or obligation to update or revise
any forward-looking statements, whether as a result of new information, future
events, or otherwise, unless required by law.

Attachments

announcement no 29-10 interim report 1 january to 30 september 2010.pdf announcement no 29-10 topotarget announces interim report 1 january-30 september 2010.pdf