Source: OxySure Systems, Inc.

OxySure (OXYS) and AED Professionals Sign Distribution Agreement

FRISCO, Texas and PALATINE, Ill., Sept. 27, 2012 (GLOBE NEWSWIRE) -- OxySure® Systems, Inc. (OTCBB:OXYS) ("OxySure") and AED Professionals ("AED Professionals") today announced they have signed a distribution agreement for AED Professionals to market and promote OxySure's flagship product, the OxySure Model 615 portable emergency oxygen device, and all related accessories. AED Professionals will offer OxySure as an add-on product to their existing installed base of Automated External Defibrillators (AEDs), and as a companion product for new AED sales. AED Professionals, General Medical Devices, Inc. company is one of the largest distributors of AEDs in the United States.

Ms. Kanchan K. Lall, Chairman and Chief Executive Officer of General Medical Devices, Inc./AED Professionals stated: "The accepted clinical protocols require the application of supplemental oxygen as soon as possible – post-resuscitation, in cardiac emergencies and cardiac arrest in particular. OxySure provides a proven, safe and easy to use solution that allows a lay rescuer to administer the oxygen, while waiting for first responders to arrive. We are pleased to partner with OxySure, as this will make us a single source supplier of AEDs and first-aid emergency oxygen equipment to meet the needs of our customers."

"We are pleased about the opportunity to work with AED Professionals," said Julian Ross, CEO of OxySure." "We believe OxySure's Model 615 is a natural complement to AEDs, which is why this partnership makes so much sense," he added.

About OxySure Systems, Inc.

OxySure Systems, Inc. is a Frisco, Texas-based medical technology company that focuses on the design, manufacture and distribution of specialty respiratory and medical solutions. The company pioneered a safe and easy to use solution to produce medically pure (USP) oxygen from inert powders. The company owns numerous issued patents and patents pending on this technology which makes the provision of emergency oxygen safer, more accessible and easier to use than traditional oxygen provision systems. OxySure's products improve access to emergency oxygen that affects the survival, recovery and safety of individuals in several areas of need: (1) Public and private places and settings where medical emergencies can occur; (2) Individuals at risk for cardiac, respiratory or general medical distress needing immediate help prior to emergency medical care arrival; and (3) Those requiring immediate protection and escape from exposure situations or oxygen-deficient situations in industrial, mining, military, or other "Immediately Dangerous to Life or Health" (IDLH) environments. www.OxySure.com

About AED Professionals

AED Professionals is a General Medical Devices, Inc. company and is a leader in the supply of products relating to medical imaging, medical diagnostics, cardio-resuscitation, patient monitoring and emergency care systems. AED Professionals is regarded as the most trusted name in AEDs and AED Supplies nationwide, and was recently awarded Preferred AED Supplier status for the New York State Dental Association. AED Professionals is the Proud Lifetime Donor of all AEDs and AED accessories needed at the 9/11 Memorial & Museum at the Ground Zero in New York City. http://www.aedprofessionals.com

Forward-Looking Statements

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Statements contained in this release that are not historical facts, including, without limitation, statements that relate to the Company's expectations with regard to the future impact on the Company's results from new products in development, may be deemed to be forward-looking statements. Words such as "expects", "intends", "plans", "may", "could", "should", "anticipates", "likely", "believes" and words of similar import also identify forward-looking statements. These statements are subject to risks and uncertainties. Forward-looking statements are based on current facts and analyses and other information that are based on forecasts of future results, estimates of amounts not yet determined and assumptions of management. Readers are urged not to place undue reliance on the forward-looking statements, which speak only as of the date of this release. Except as may be required under applicable law, we assume no obligation to update any forward-looking statements in order to reflect any event or circumstance that may arise after the date of this release. Additional information on risks and other factors that may affect the business and financial results of OxySure Systems, Inc. can be found in the filings of OxySure Systems, Inc. with the U.S. Securities and Exchange Commission.

Media Contact(s):

Yves Dezawy

(646) 546-5151

Yves@OxySure.com

www.OxySure.com

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