Protea Expands Its Global Distribution Network

Establishes New Sales Outlets in Spain, Portugal, Poland, Israel and Turkey

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| Source: Protea Biosciences, Inc.

MORGANTOWN, W.Va., Oct. 4, 2012 (GLOBE NEWSWIRE) -- Protea, a leader in the field of bioanalytics, announced today it has established new international distributor partnerships, in Israel (Yair Technologies), Poland (BioAnalytic), Spain and Portugal (Irida Iberica S.L.), and Turkey (IDL Teknolojik).

"These new distribution agreements reflect our continued, successful expansion of our global bioanalytical product marketing," stated Dr. Alessandro Baldi, Protea's Vice President and General Manager. "These partners join Protea's existing network of international distributors. Along with Protea's growing lines of sample preparation and mass spectrometry products, our new distributors will also be marketing Protea's award winning LAESI DP-1000 instrument."

On June 28th Protea was also awarded the "Governor's Commendation for International Market Entry" by Governor Earl Ray Tomblin. This awarded recognizes West Virginia companies engaged in international sales to new markets.

Protea is a world leader in the development of new products that improve medical researcher's ability to analyze biological samples (including tissues, biopsies, blood and other biofluids). In operation for over 11 years, Protea continues to support researchers on the cutting edge of discovery; strengthening the sciences of biomolecular separation and biomolecular imaging by providing innovations for bioanalytics.

About Protea Biosciences Group, Inc.

Protea (www.proteabio.com) is focused on the development of new bioanalytical technologies that enable the direct analysis of proteins, metabolites, and other biomolecules. Its Bioanalytical Services organization provides expertise and innovation to support projects from concept to knowledge.

The Protea Biosciences, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=10808

Forward-Looking Statements

This press release may contain certain statements relating to future results which are forward-looking statements. These statements are not historical facts, but instead represent only the Company's belief regarding future events, many of which, by their nature, are inherently uncertain and outside of the Company's control. It is possible that the Company's actual results and financial condition may differ, possibly materially, from the anticipated results and financial condition indicated in these forward-looking statements. Further information concerning the Company and its business, including factors that potentially could materially affect the Company's financial results, are contained in the Company's filings with the Securities and Exchange Commission. All forward-looking statements included in this press release are made only as of the date of this press release, and we do not undertake any obligation to publicly update or correct any forward-looking statements to reflect events or circumstances that subsequently occur or of which we hereafter become aware.

Protea website: www.proteabio.com

About LAESI: https://proteabio.com/LAESI

https://proteabio.com/LAESI/Resources/videos/LAESI+DP-1000+-+see+beyond

For more Information:
Protea Biosciences Group, Inc.
955 Hartman Run Road, Morgantown, WV 26507 USA
Phone: 304.284.2600
Fax: 304.292.7101