Apricus Biosciences Announces 2012 Year End Financial Results Conference Call

Conference Call/Webcast to be Held Monday, March 18, 2013 at 1:00 p.m. ET

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| Source: Apricus Biosciences, Inc.

SAN DIEGO, March 14, 2013 (GLOBE NEWSWIRE) -- Apricus Biosciences, Inc. ("Apricus Bio" or the "Company") (Nasdaq:APRI) (www.apricusbio.com) announced today that it will hold a conference call to discuss its year end 2012 financial results and recent corporate highlights on Monday, March 18, 2013 at 1:00 p.m. ET. The Company expects to file its Form 10-K for the year ended December 31, 2012 on Monday, March 18, 2013.

The call can be accessed in the U.S. by dialing 877-407-8031 and outside of the U.S. by dialing 201-689-8031 and asking the conference operator for the Apricus Bio Conference Call. The teleconference replay will be available for one week by dialing in the U.S. 877-660-6853 and outside of the U.S. by dialing 201-612-7415. Replay passcode 410469 is required for playback. The conference call will also be webcast live at http://www.investorcalendar.com/IC/CEPage.asp?ID=170645. The webcast replay will be available for three months.

About Apricus Biosciences, Inc.

Apricus Biosciences, Inc. (Nasdaq:APRI) is a pharmaceutical company that develops and markets innovative treatments that help large patient populations across numerous, large-market therapeutic classes including male and female sexual health. The Company has one approved product, Vitaros®, for the treatment of erectile dysfunction, which will be marketed in Canada by Abbott Laboratories, and Femprox®, a product candidate, for the treatment of female sexual arousal disorder, which successfully completed a nearly 400-subject Phase III study in China.

For further information on Apricus Bio, visit http://www.apricusbio.com. You can also receive information at http://twitter.com/apricusbio.

Apricus Bio Investor Relations:

David Pitts or Lourdes Catala
Argot Partners
212-600-1902