BIOTIE THERAPIES CORP. Stock Exchange Release 28 February 2014 AT 8.50 AM Biotie: Change in the number of votes Biotie Therapies Corp. ("Biotie" or the "Company") has conveyed Biotie shares held as treasury shares and that were issued on 2 January 2014 pursuant to the Stock Option Plan 2011 and the Equity Incentive Plan 2011 as follows: Shares conveyed Cumulative shares conveyed Remaining shares to be since 2 January 2014 conveyed 15,000 338,750 2,982,910 Under the Stock Option Plan 2011, the owners of the stock options may subscribe for a maximum total of 7,401,000 new shares in the Company or existing shares held by the Company. No shares have been subscribed for during the period 28 January 2014 and 27 February 2014. The first vesting period of the Equity Incentive Plan 2011 ended on 5 January 2014, after which the Company's shares shall be delivered to employees on the basis of the granted share units. It was resolved pursuant to the authorization of the Annual General Meeting of the Shareholders held on 4 April 2013 to issue 15,000 existing treasury shares to the employees without consideration for the purposes of remunerating the employees pursuant to the terms and conditions of the Equity Incentive Plan 2011 and thus, there is an especially weighty financial reason to derogate from the pre-emptive right of the shareholders, as referred to in Chapter 9 Section 4(1) of the Companies Act (624/2006, as amended). The conveyed shares previously held as treasury shares have not carried any voting rights. The conveyance does not affect the number of registered shares. After the conveyances the changes are as follows: Increase in number of Total amount of Number of the Total number outstanding shares voting rights Company's shares held of registered by the Group shares 15,000 446,552,698 9,479,700 456,032,398 Turku, 28 February 2014 Biotie Therapies Corp. Timo Veromaa, President and CEO For further information, please contact: Virve Nurmi, Investor Relations Manager, Biotie Therapies Corp. tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com www.biotie.com DISTRIBUTION: NASDAQ OMX Helsinki Ltd Main Media [HUG#1765332]