DGAP-News: Neovacs S.A.: Stellar Biotechnologies and Neovacs S.A. Expand KLH Supply Relationship


DGAP-News: Neovacs S.A. / Key word(s): Miscellaneous
Neovacs S.A.: Stellar Biotechnologies and Neovacs S.A. Expand KLH
Supply Relationship

01.04.2015 / 08:00

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Stellar Biotechnologies and Neovacs S.A. Expand KLH Supply Relationship

Companies Sign KLH Supply Agreement for Neovacs' Kinoid Clinical Trials and
Initial Commercialization

PORT HUENEME, CA and PARIS, FRANCE, (April 1st, 2015) -- Stellar
Biotechnologies, Inc. ("Stellar" or the "Company") (OTCQB: SBOTF) (TSX-V:
KLH) and Neovacs S.A., ("Neovacs") (Alternext Paris: ALNEV) today announced
that the Companies have entered into an expanded supply agreement to meet
Neovacs' requirements for Keyhole Limpet Hemocyanin (KLH), a primary
component of Neovacs' proprietary Kinoid immunotherapy technology.

The new agreement extends and expands the supply contracts previously in
place between the Companies, in order to ensure the continued supply of
Stellar KLH(TM) to Neovacs during its Kinoid clinical trials and to support
the expected commercial roll-out of Neovacs' lead product candidate
IFNα-Kinoid, an immunotherapy being developed for the treatment of systemic
lupus erythematosus ("lupus").

Stellar is a leader in the sustainable manufacture of KLH, an
immune-stimulating protein widely used as a carrier molecule in
immunotherapies under development for a variety of disease indications.
Immunotherapy uses a patient's own immune system to target and treat
diseases. KLH can only be produced from a scarce marine source. Stellar
believes it is the only company with the proprietary technology to manage
sustainable, scalable production of GMP quality KLH to meet future
pharmaceutical industry demands.

Neovacs is a leader in the development of active immunotherapies for the
treatment of chronic autoimmune diseases. Neovacs' patented Kinoid
technology combines a select cytokine of interest attached to KLH as the
immune-stimulating carrier protein. The resulting immunotherapy uses the
patient's immune system to generate antibodies against the targeted
disease.

Neovacs' lead product candidate, IFN(-Kinoid, has successfully completed a
Phase I/IIa clinical trial for lupus. The Company's Scientific Advisory
Board (SAB) members have announced their full support for the planned Phase
IIb trial of IFNα-Kinoid in approximately 160 patients in Europe, Latin
America and Asia. This Phase IIb study is expected to begin mid-2015. A
U.S. Phase IIa trial of IFNα-Kinoid for the treatment of lupus in the U.S.
is expected to commence by early 2016.

"We have enjoyed a long-standing and successful relationship with Stellar
Biotechnologies as our key KLH supplier," said Miguel Sieler, Chief
Executive Officer of Neovacs. "This new agreement with Stellar comes at a
pivotal point for Neovacs, as we are preparing to launch multicenter
clinical trials with IFNα-Kinoid and are strengthening our U.S. operations
through the recent formation of a wholly-owned subsidiary, Neovacs, Inc.
The new supply agreement will ensure that Neovacs has access to a scalable,
stable supply of GMP grade KLH as our Kinoid products advance through
clinical development and we prepare for the expected commercial launch."

"Expanding our supply commitment to Neovacs to include late-stage clinical
trials and expected initial commercialization is an excellent demonstration
of the growing commercial prospects for our core KLH business," said Frank
Oakes, President and CEO of Stellar Biotechnologies. "We also see this is
as positive validation for the use of Stellar KLH(TM) in the development of
new immunotherapy treatments."

Under the terms of the agreement, Neovacs will purchase Stellar KLH(TM) for
use in its proprietary KLH-based Kinoid immunotherapies in the European
Union, Latin America, Asia, the U.S. and Canada. Neovacs will use Stellar
KLH(TM) for its planned Phase II and Phase III clinical trials and for
expected commercial manufacturing of its products for up to one year
following market approval. Neovacs will manage and fund all product
development and regulatory submissions for its immunotherapy products and
act as the sponsor company for the future clinical trials. Stellar will
supply GMP grade KLH to Neovacs according to agreed specifications,
quantities, and pricing, as well as maintain a master file with the U.S.
FDA for the KLH product. Stellar will also provide professional, technical,
and regulatory support to Neovacs. The agreement has an initial five-year
term, which may be renewed by Neovacs in one-year increments.

About Neovacs

Neovacs (Alternext Paris: ALNEV) is a leading biotechnology company focused
on an active immunotherapy technology platform (Kinoids) with applications
in autoimmune and/or inflammatory diseases. On the basis of the company's
proprietary technology for inducing a polyclonal immune response (covered
by five patent families that potentially run until 2032) Neovacs is
focusing its clinical development efforts on IFNα-Kinoid, an immunotherapy
being developed for the indication of lupus. Neovacs is also conducting
preclinical development works on other therapeutic vaccines in the fields
of auto-immune diseases, oncology and allergies. The goal of the Kinoid
approach is to enable patients to have access to safe treatments with
efficacy that is sustained in these life-long diseases.

For more information on Neovacs, visit www.neovacs.fr

About Stellar Biotechnologies, Inc.

Stellar Biotechnologies, Inc. (OTCQB: SBOTF) (TSX-V: KLH) is a leader in
sustainable manufacture of Keyhole Limpet Hemocyanin (KLH), an important
immune-stimulating protein used in wide-ranging therapeutic and diagnostic
markets. KLH is both an active pharmaceutical ingredient (API) in many new
immunotherapies (targeting cancer, immune disorders, Alzheimer's, and
inflammatory diseases) as well as a finished product for measuring immune
status. Stellar Biotechnologies is unique in its proprietary methods,
facilities, and KLH technology. It is committed to meeting the growing
demand for commercial-scale supplies of GMP grade KLH, ensuring
environmentally sound KLH production, and developing KLH-based active
immunotherapies.

Visit www.stellarbiotech.com and the Stellar KLH knowledge base
www.klhsite.org.

Stellar Biotechnologies Company Contact:

Mark A. McPartland
Vice President of Corporate Development and Communications
+1 (805) 488-2800 ext. 103
markmcp@stellarbiotech.com 
www.stellarbiotech.com

Neovacs Company Contacts:
    
NEOVACS - Investor Relations
Nathalie Trépo
+33 (0)1 53 10 93 00
ntrepo@neovacs.com

Investor Relations / Financial Communications - NewCap 
Valentine Brouchot / Pierre Laurent
+33 (0)1 44 71 94 94
theradiag@newcap.fr

Investor Relations / Financial Communications Germany - MC Services
Raimund Gabriel
+49-89-210228-30
raimund.gabriel@mc-services.eu

Press / U.S. Inquiries - The Ruth Group
Melanie Sollid-Penton
1.646.536.7023
msollid@theruthgroup.com



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Language:    English                                                   
Company:     Neovacs S.A.                                              
             3-5, Impasse Reille                                       
             75014 Paris                                               
             France                                                    
Phone:       +33 (0)1 53 10 93 00                                      
Fax:         +33 (0)1 53 10 93 03                                      
E-mail:      www.neovacs.fr                                            
Internet:    info@neovacs.fr                                           
ISIN:        FR0004032746                                              
WKN:         A1CVKR                                                    
Listed:      Regulated Unofficial Market in Stuttgart; Open Market in  
             Frankfurt                                                 
 
 
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