Director/PDMR Shareholding

Transaction by Person Discharging Managerial Responsibilities
Disclosure Rule DTR 3.1.4

On 8 May 2015, Marc Dunoyer, a Director of the Company, notified us that, on 7
May 2015, he purchased 10,000 AstraZeneca PLC Ordinary Shares of $0.25 each at a
price of 4397 pence per share.

A C N Kemp
Company Secretary
8 May 2015