Number of shares and votes in Orexo

Uppsala, Sweden – July 31, 2015 – The number of shares and votes in Orexo AB
have changed as a result of that the company has repurchased the entire issue of
class C shares.

Today, the last trading day of the month, there are in total 34,580,810 shares -
whereof 34,445,810 are ordinary shares and 135,000 class C shares - and
34,459,310 votes in the company.

For further information, please contact:
Henrik Juuel, EVP and Chief Financial Officer
Tel: +46 (0)18-780 88 00, E-mail: ir@orexo.com

About Orexo
Orexo is a specialty pharmaceutical company commercializing its proprietary
product Zubsolv® for maintenance treatment of opioid dependence in the US.
Zubsolv is an advanced formulation of buprenorphine and naloxone using Orexo’s
unique knowledge and expertise in sublingual drug delivery. R&D is focusing on
reformulation of known substances to new improved products that meet great unmet
medical needs by using its patented proprietary technologies. Orexo’s share is
listed on Nasdaq Stockholm Exchange Mid Cap (STO: ORX) and is available as ADRs
on OTCQX (ORXOY) in the US. Orexo’s global headquarters and R&D are based in
Uppsala, Sweden.

For information about Orexo please visit www.orexo.com