AstraZeneca appoints Dr Sean Bohen


ASTRAZENECA APPOINTS DR SEAN BOHEN AS EXECUTIVE VICE PRESIDENT OF GLOBAL
MEDICINES DEVELOPMENT AND CHIEF MEDICAL OFFICER

AstraZeneca today announced the appointment of Sean Bohen MD, PhD, as Executive
Vice President of Global Medicines Development and Chief Medical Officer. He
will join the company on 15 September.

Dr. Bohen will be responsible for driving the progress of AstraZeneca's
portfolio of small molecules and biologics investigational medicines through
late-stage development to regulatory approval. As Chief Medical Officer, he will
be responsible for patient safety across the entire AstraZeneca and Medimmune
portfolio.

Dr. Bohen joins AstraZeneca from Genentech where he was most recently Senior
Vice President of Early Development. He oversaw preclinical and clinical
development programmes across all therapy areas, including oncology, respiratory
and autoimmune diseases, to deliver trial-ready drug candidates to late-stage
development. Before this, he held a number of positions in early and late-stage
development, playing a key role in the growth and progress of the
Genentech/Roche portfolio. Dr. Bohen was instrumental in bringing a large number
of new medicines to patients, in particular for cancer, and led activities to
incorporate diagnostics into clinical programmes.

Prior to joining Genentech, Dr. Bohen was a Clinical Instructor in Oncology at
Stanford University School of Medicine, a research associate at the Howard
Hughes Medical Institute and a postdoctoral fellow at the National Cancer
Institute.

Pascal Soriot, Chief Executive Officer, said: "I'm delighted to welcome Sean to
AstraZeneca at a very exciting time for our company. Our continued strategic
investment in science is driving momentum across all therapy areas. Sean is a
tremendous scientist and an accomplished drug developer. His impressive
expertise in key areas of our exciting pipeline, including oncology and
immunology, will further strengthen and accelerate the delivery of new medicines
for patients. His extensive diagnostics experience will also reinforce our
efforts in precision medicine."

Dr. Bohen will be a member of AstraZeneca's Senior Executive Team, reporting
into Pascal Soriot. He is a graduate of the University of Wisconsin-Madison and
later earned his doctorate in biochemistry and his medical degree at the
University of California, San Francisco.

NOTES TO EDITORS

To obtain a photograph of Dr. Bohen, please visit
www.astrazeneca.com/media/photo-library or contact the global media relations
team (details below).

About AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business that
focuses on the discovery, development and commercialisation of prescription
medicines, primarily for the treatment of cardiovascular, metabolic,
respiratory, inflammation, autoimmune, oncology, infection and neuroscience
diseases. AstraZeneca operates in over 100 countries and its innovative
medicines are used by millions of patients worldwide. For more information
please visit: www.astrazeneca.com

CONTACTS

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Key: RIA - Respiratory, Inflammation and Autoimmunity, CVMD - Cardiovascular and
Metabolic Disease,

ING - Infection, Neuroscience and Gastrointestinal

24 August 2015

-ENDS-

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