ASTRAZENECA COMPLETES DIVESTMENT OF CAPRELSA


ASTRAZENECA COMPLETES DIVESTMENT OF RARE DISEASE MEDICINE CAPRELSA

AstraZeneca has announced the global completion of the divestment of Caprelsa®
(vandetanib), a rare disease medicine, to Genzyme, a Sanofi company.

Genzyme made an upfront payment to AstraZeneca of $165 million to acquire the
global rights to sell and develop Caprelsa, and will make further development
and sales milestone payments of up to $135 million. The transaction does not
include the transfer of any AstraZeneca employees or facilities.

The divestment reinforces AstraZeneca's strategic focus on its three main
therapy areas. As an asset divestment, the upfront receipt and any subsequent
payments for the agreement will be reported in Other Operating Income in the
Company's financial statements. The transaction does not impact AstraZeneca's
financial guidance for 2015.

About AstraZeneca
AstraZeneca is a global, innovation-driven biopharmaceutical business that
focuses on the discovery, development and commercialisation of prescription
medicines, primarily for the treatment of cardiovascular, metabolic,
respiratory, inflammation, autoimmune, oncology, infection and neuroscience
diseases. AstraZeneca operates in over 100 countries and its innovative
medicines are used by millions of patients worldwide. For more information
please visit: www.astrazeneca.com

CONTACTS

Media Enquiries
Esra Erkal-Paler                     UK/Global         +44 20 7604 8030
Vanessa Rhodes                       UK/Global         +44 20 7604 8037
Ayesha Bharmal                       UK/Global         +44 20 7604 8034
Karen Birmingham                     UK/Global         +44 20 7604 8120
Jacob Lund                           Sweden            +46 8 553 260 20
Michele Meixell                      US                +1 302 885 2677
Investor Enquiries
UK
Thomas Kudsk Larsen   Oncology       +44 20 7604 8199  +44 7818 524185
Eugenia Litz          RIA            +44 20 7604 8233  +44 7884 735627
Nick Stone            CVMD           +44 20 7604 8236  +44 7717 618834
Craig Marks           ING            +44 20 7604 8591  +44 7881 615764
Christer Gruvris                     +44 20 7604 8126  +44 7827 836825
US
Lindsey Trickett      Oncology, ING  +1 301 398 5118   +1 240 543 7970
Mitch Chan            Oncology       +1 301 398 1849   +1 301 398 1849
Dial / Toll-Free                     +1 301 398 3251    +1 866 381 7277

Key: RIA - Respiratory, Inflammation and Autoimmunity, CVMD - Cardiovascular and
Metabolic Disease,
ING - Infection, Neuroscience and Gastrointestinal

7 October 2015

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