Fibrocell and Intrexon Announce Poster Presentation on FCX-007 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB) at American Society of Human Genetics Annual Meeting
Highlights in vivo Pre-Clinical Data for Potential First-in-Class Treatment for RDEB
October 08, 2015 08:05 ET
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Trust;Fifth Street Senior Floating Rate Corp.;Fifth Street Senior Floating Rate Corp.;Professional Diversity Network, Inc., Lightbridge Corp., Energy Fuels, Inc., Methes Energies International Ltd.;Calpian, Inc., Legacy Education Alliance, Inc., Bitcoin Shop, Inc., Lattice Incorporated;U-Vend,Inc.;Apollo Medical Holdings, Inc.;BioCorRx, Inc.;Intrexon Corporation;SSP;Royal Philips;New Generation Consumer Group, Inc.;Midrex Technologies, Inc.;RFMW Ltd.;Shenandoah Telecommunications Co;Medical Marijuana, Inc.;University of Colorado;LinnCo, LLC;Jiangsu Hengrui Medicine Co., Ltd.;Legacy Education Alliance, Inc.;Tekmira Pharmaceuticals Corporation;Diamondback Energy, Inc.;Sprott Physical Gold Trust;Sprott Physical Silver Trust;LinnCo, LLC ;Pascack Bancorp, Inc.;National Charity League, Inc., Glendale Chapter;Windstream ;Diamondback Energy, Inc.;Acasti Pharma Inc.;Rose Rock Midstream L.P.;SemGroup Corporation;Sprott Physical Gold Trust;Sprott Physical Silver Trust;New Penn;Reddaway;Holland;Merck;Genome Compiler Corp.;Shenandoah Telecommunications Co;Rethink Robotics;New Penn;Reddaway;Holland;Cancer Genetics, Inc.;Apollo Medical Holdings, Orbital Tracking;Zimbra;Visible Alpha;Immuron Limited;Lattice Incorporated ;Legacy Education Alliance, Inc.;LinnCo, LLC ;STEMCELL Technologies;State Investors Bancorp, Inc.;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Blyth, Inc.;Shared-Use Mobility Center;LinnCo, LLC;LinnCo, LLC ;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Reddaway, Holland;American Water Works;Apollo Medical Holdings;A.H. Belo;Global Brands Group Holding Limited;Sprott Physical Gold Trust;Sprott Physical Silver Trust
;Independence Holding Company;Imagine Communications Corp.;E4 Computer Engineering;Collagen Solutions plc;BNY Mellon;Dynetics Inc.;Sirona Dental Systems Inc.;Square 1 Financial, Inc.;Medical Marijuana, Inc.;BASF;Intrexon Corporation;Pineapple Express, Inc.;TeamConnor Childhood Cancer Foundation;Cabinet Grow, Inc.;CenterPoint Energy, Inc.;Transeastern Power Trust;Baxalta Incorporated;Targa Resources Corp.;LinnCo, LLC;AD;Domain Real Estate Partners, LLC ;Intrexon Corporation;Transeastern Power Trust;Rose Rock Midstream, L.P.;NewBridge Bancorp;AppYea Inc.;Distilled Spirits Council;Infor;Bristol-Myers Squibb;ARMO BioSciences, Inc.;Envestnet;Terra Tech Corp.;Targa Resources Corp.;SmartCard Marketing Systems;Linn Co, LLC;Green Plains Partners LP;Foundation for a Drug-Free World;Sprott Physical Gold Trust;Sprott Physical Gold Trust;Reis, Inc;TriVascular Technologies, Inc.;LinnCo;PositiveID Corporation;State Investors Bancorp, Inc.;Viper Energy Partners LP;Furmanite Corporation;Western Refining, Inc.;Murphy USA Inc.;Targa Resources Corp.;Diamondback Energy, Inc.;Windsor Castle Park Foundation;LinnCo;Pomerantz LLP;Baxalta Incorporated;Fifth Street Senior Floating Rate Corp. ;Momentous Entertainment Group;LinnCo, LLC;Targa Resources Partners LP;SemGroup Corporation;UIL Holdings Corporation;TriVascular Technologies, Inc.;AEON Clinical Laboratories;Sprott Physical Gold Trust, Sprott Physical Silver Trust;Capital Bank Financial Corp. ;Rocky Mountain Ayre, Inc.;SmartCard Marketing Systems Inc.;STG Group, Inc.;STG Group, Inc.;Sprott Physical Gold Trust, Sprott Physical Silver Trust;Trax;BioElectronics Corporation;Seen On Screen TV, Inc.;Targa Resources Corp.;Sprott Physical Gold Trust,Sprott Physical Silver Trust;Rose Rock Midstream, L.P.;Sprott Physical Gold Trust, Sprott Physical Silver Trust;Wilshire Bancorp, Inc.;Wilshire Bancorp, Inc.;Broadcom Corporation;The Johnson Studio;Sprott Physical Gold Trust, Sprott Physical Silver Trust;BASF;Sprott Physical Gold Trust, Sprott Physical Silver Trust;Daiichi Sankyo, Inc.;American Securities, P2 Capital Partners;Borsa Istanbul;Towers Watson;Zenbanx;Zenbanx;Hopewell Valley Community Bank;Pierre Fabre Laboratories;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Sprott Physical Gold Trust;TowneBank;Hopkins Bancorp, Inc.;Baxalta Incorporated;Western Refining, Inc.;Terra Tech Corp.;Turkcell;Intrexon Corporation;Independence Holding Company;Cape Bancorp, Inc.;Tel Aviv Stock Exchange;The General;The Conservation Fund;CenterPoint Energy, Inc.;Auscrete Corporation;Rose Rock Midstream, L.P.;Baxalta Incorporated;Anchor BanCorp Wisconsin Inc.;Envoy Group Corp.; 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YRC Worldwide;Striped Pig Distillery;Pulaski Financial Corp.;American Independence Corp.;CorreLog;MonoSol Rx;USI;CenterPoint Energy, Inc.;LinnCo;Wilshire Bancorp, Inc.;Advanced Medical Isotope Corporation ;PureSnax International, Inc. ;Consensus;Rose Rock Midstream;Navios Maritime Acquisition Corporation;Polycom;LinnCo, LLC;Efma;LinnCo, LLC;Intrexon Corporation;iStream Financial Services;Roc Nation;SnipGold Corp.;Microchip Technology;PetroShare Corp.;AbbVie;Green Plain Partners LP;Rocky Mountain High Brands, Inc.;LinnCo, LLC;Black Knight Financial Services, Inc.;Advanced Analytical Technologies, Inc.;LinnCo, LLC ;Behavioral Health Center of Excellence ;Cape Bancorp, Inc.;Advanced Medical Isotope Corporation;Auscrete Corporation;Viper Energy Partners LP;Diamondback Energy, Inc.;Garmin Ltd.;Gritstone Oncology;Vifor Pharma;FlexFridge Inc.;Royal Philips;LinnCo.;ascribe;Wilshire Bancorp, Inc.;LinnCo, LLC;Hudson & Marshall;Excalibur Resources Ltd.;Wilshire Bancorp, Inc.;Medical Marijuana, Inc. ;Townsquare Media;Prime Care Technologies;Pfizer Inc. ;Interstate Batteries;Harmony Bank;Advanced Distribution Solutions, Inc.;LinnCo, LLC;LINN Energy, LLC;Avoka;Rose Rock Midstream, L.P.;Rose Rock Midstream;SnipGold Corp.;Rocky Mountain High Brands;Westwood Holdings Group, Inc.
Cadiz, Inc.;iDreamSky Technology Limited ;Impact Telecom;CNS Response, Inc.;Akers Biosciences, Inc.;Inteliquent, Inc.;Meridian Audio;Triax,Unitron Group;Triax;Unitron Group;Global Invacom Group Limited;MARUSYS;Diamondback Energy, Inc.;Fifth Street Senior Floating Rate Corp.;Fujitsu America, Inc.;CB Financial Services, Inc.;Diamondback Energy, Inc.;First Citizens Bancorporation, Inc.;ZAIS Group, LLC;Udi's Gluten Free;LinnCo, LLC;Blue Bird Corporation;CB Financial Services, Inc.;Nielsen;Rose Rock Midstream;Western Refining, Inc.;CB Financial Services, Inc.;7digital;Horizon Technology Finance Corporation;Bernstein Litowitz Berger & Grossmann LLP ;Fifth Street Senior Floating Rate Corp.;LinnCo, LLC;LinnCo, LLC;Globe Specialty Metals Inc. ;The Channel Company;American Water Works Company, Inc.;Top Ships, Inc.;Energy Fuels, Inc.;ForceField Energy, Inc.;Profire Energy, Inc.;InterCloud Systems, Inc.;Lattice, Inc.;GlyEco, Inc.;Quadrant 4 System Corp.;Bitcoin Shop, Inc.;Iveda Solutions, Inc., Direct Insite Corp., Drone Aviation Holding Corp., Big North Graphite Corp., The Coin Tree;Starstream Entertainment, Inc., Giggles N' Hugs, Inc., StationDigital Corp., Exeo Entertainment, Inc., I-Tap, Inc.;Clal Biotechnology Industries Ltd.;Presbyterian Senior Living;Actinium Pharmaceuticals, Inc.;Pac-12 Networks;NETGEAR, Akers Biosciences, TOP Ships;Rose Rock Midstream, L.P.;LinnCo, LLC;SoftIron;Cosmodyne, LLC;Cosmodyne, LLC;aioTV;Fyffes;Targa Resources Corp.;Western Refining, Inc.;Targa Resources Corp. ;Diamondback Energy, Inc.;Azteca America;Fundacion Azteca America;RBC Wealth Management;RBC Wealth Management;Targa Resources Corp.;BBC Worldwide;Market America, Inc. & SHOP.COM;LinnCo, LLC;eBay;Baker Donelson;Riverside Bank;Viper Energy Partners LP;Takeda Pharmaceutical Company Limited;OxySure Systems, Inc.;Southwest Airlines;LinnCo, LLC;Berkshire Hills Bancorp, Inc.;The Care and Concern Free Health Clinic;LifeLock, Inc.;Diamondback Energy, Inc.;Panasonic Corporation;Actinium Pharmaceuticals;SemGroup Corporation;Rose Rock Midstream L.P.;Fifth Street Senior Floating Rate Corp.;Valley Community Bank ;Actinium Pharmaceuticals, Inc.;Aptys Solutions;Cancer Genetics, Inc. ;E4 Computer Engineering;NXP Semiconductors N.V.;Bristol-Myers Squibb Company, Pfizer Inc.;Profire Energy;BNC Bancorp;Bigstock;DCR Strategies Inc. | TruCash;Akers Biosciences Inc.;OxySure Systems, Inc.;NETGEAR;TESARO, Inc.;Lattice Incorporated;Perritt Capital Management;Merck;Holland;Bristol-Myers Squibb;GlyEco, Inc.;LinnCo, LLC;The Home Depot;Lionbridge Technologies, Inc.;NatureWorks;TriQuint Semiconductor, Inc. ;Perspecta Trust LLC ;Fluor Corporation ;Rose Rock Midstream, L.P.;j2 Global;INC Research, Inc. ;Targa Resources Corp.;Holland;Women's Health USA;BillerudKorsnas AB;Oregon Health & Science University;LinnCo, LLC ;Y-TEC;Beyond Semiconductor;Trulia, Inc.;Holland;Diamondback Energy, Inc.;Federal Home Loan Bank of Seattle ;Phoenix Bancorp, Inc.;State Investors Bancorp, Inc. ;LinnCo, LLC;Akers Biosciences, Inc.;Sensory, Inc.;Targa Resources Corp.;American Red Cross;ProSyst;Otsuka Pharmaceutical Development & Commercialization, Inc.;Fifth Street Senior Floating Rate Corp.;Leapfrog;Phoenix Bancorp, Inc.;Cash Connect;Loomis;OnCore Biopharma, Inc.;Invetech Pty Ltd;Giggles N' Hugs, Inc.;LINN Energy, LLC;Princess Grace Hospital;Jack I. Zwick, Esq.;eWorld Companies, Inc.;Diamondback Energy, Inc.;NeuroBioPharm Inc.;Targa Resources Corp.;All Medical Solutions;The Medical Alliance, Inc.;Holland;SQN Banking Systems;Energy Fuels, Inc., Trecora Resources, Zivo Bioscience, Inc., AV Therapeutics, Inc., Lattice, Inc.;Targa Resources Corp. ;Cell Therapy Catapult;Allpoint Network;Targa Resources Partners LP;Rose Rock Midstream, L.P. ;Targa Resources Partners LP;ForceField Energy Inc.;Rose Rock Midstream, L.P.;Bristol Myers-Squibb;LinnCo, LLC;MaxLinear, Inc.;LinnCo, LLC;Acasti Pharma Inc.;Discovery Center of Idaho ;Courier Corporation ;QEST;LinnCo, LLC;BMV Group;Diamondback Energy, Inc.;Facilis Technology;Expedia, Inc.;Targa Resources Corp.;Viper Energy Partners LP;BMC Software, Inc. ;Centrosolar America, Inc.;Hanse Orga;Diamondback Energy, Inc.;OncoSec Medical Inc.;Stemgent;RM Auctions;LinnCo, LLC;AV Therapeutics, Inc.;Kyocera Communications Inc.;Walgreens;Liberty Mutual Insurance;Rose Rock Midstream, L.P.;Qualys, Inc.;Rose Rock Midstream;SemGroup Corporation;Reddaway;Federal Home Loan Bank of Seattle;MaxLinear, Inc.;Targa Resources Partners LP;NantHealth;LinnCo, LLC;thePlatform;Alliance Bancorp, Inc. of Pennsylvania;American Airlines Center;Bell Helicopter;Northpointe Bank;YRC Freight;Trading Technologies;OptionsCity Software;Orc;Quadrant 4 Systems Corp;OxySure Systems Inc;Lattice Inc.;Asia Pacific Stock Exchange;Inovalon;Nintendo Co., Ltd.;GridPoint;Holland;Pacific Coast Producers;Acasti Pharma Inc.;Noble Markets;Courier Corporation;LinnCo, LLC, Quantum Energy Partners ;YRC Freight;Rose Rock Midstream;CUR Media, Legacy Education Alliance, Apollo Medical Holdings;Fujifilm Holdings Corporation;Intrexon Corporation;Bitcoin Shop Inc.;Towers Watson & Co;Servier;Sporting Kansas City;LinnCo, LLC ;OxySure Systems, Inc.;Comptel Oyj;LinnCo, LLC;Putnam County Savings Bank;Outbrain Inc.;Squalan Natural Health B.V.;Lattice Incorporated;Trinity Health;Buena Vida Media;1347 Property Insurance Holdings, Inc., Cancer Genetics, Inc., Galectin Therapeutics, Inc., OxySure Systems, Inc., TOP Ships, Inc.;Asure Software, Inc.;CUR Media, Inc.;Bitcoin Shop, Inc.;Giggles N� Hugs, Inc.;Vapir Enterprises, Inc. ;Lightbridge Corp.;Profire Energy, Inc.;Lattice, Inc.;StationDigital, Inc.;Texas Rare Earth Resources, Inc.;Cardio3 BioSciences;Akers Biosciences, Inc., Arch Therapeutics, Inc., Zivo Bioscience, Inc., AV Therapeutics, Inc., Legacy Education Alliance, Inc.;Medytox Solutions, Inc.;Medytox Solutions, Inc.;Rose Rock Midstream
;Cardio3 BioSciences;LRR Energy, L.P.;Palmetto Bancshares, Inc.;New Penn;CareWell Urgent Care;MedImmune;Early Warning;CUR Media, Inc.;Fortress Biotech, Inc.;Kajeet;LinnCo, LLC;Bleckmann;Nordson Corporation;The Burlington Capital Group;Materialise;LinnCo LLC;Targa Resources Corp.;Cardio3 BioSciences;Juno Therapeutics, Inc.;Margaritaville Enterprises ;Diamondback Energy, Inc.;Fliphound ;SEPHORA;Florida Turbine Technologies, Inc.;Amazing Charts;Cancer Genetics, Inc.;Toyota;ProSyst;GreenPocket;Sorrento Therapeutics, Inc.;SmallCapVoice.com, Inc.;ReviveHealth;ReviveHealth;MeadWestvaco Corporation;Cancer Genetics, Inc.;Legacy Education Alliance, Inc.;StationDigital Corporation;VaultLogix;bluebird bio, Inc. ;Sprott Physical Gold Trust;Sprott Physical Silver Trust;OxySure Systems, Inc.;Appliance Recycling Centers of America;Ecobank;Pacific Coast Producers ;The Hamburg Port Authority;Open Access Technology International;LinnCo, LLC ;AppYea, Inc.;Valeant Pharmaceuticals International, Inc.;Pazoo, Inc.;ZenBanx Holding Ltd.;Jonas Fitness;Cancer Genetics Inc., Giggles N' Hugs Inc.;Intrexon Corporation;Building Materials Holding Corporation ;SmallCapVoice.com;Tokio Marine Holdings, Inc.;Nuveen Investments;Rambam Health Care Campus;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Jamba Juice;Harmonix Music Systems, Inc.;Merz North America, Inc.;HNA Group;Sprott Inc.;Mediacom Communications Corporation;Calpian, Inc.;Marriott International;Colliers International Group Inc ;Colliers International Group Inc.;Kofi Annan Foundation;bluebird bio, Inc.;KKM Financial;Martha Stewart Living Omnimedia, Inc.;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Sprott Physical Gold Trust;Chris4Life Colon Cancer Foundation;Dinaco;ZestFinance;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Rhonda's Kiss;Usina Sao Martinho;LinnCo, LLC;LinnCo, LLC;Freescale Semiconductor ;Rose Rock Midstream;LinnCo, LLC;LinnCo, LLC;LinnCo, LLC;Sprott Physical Gold Trust;Sprott Physical Silver
Trust;Fifth Street Senior Floating Rate Corp.;Fifth Street Senior Floating Rate Corp.;Professional Diversity Network, Inc., Lightbridge Corp., Energy Fuels, Inc., Methes Energies International Ltd.;Calpian, Inc., Legacy Education Alliance, Inc., Bitcoin Shop, Inc., Lattice Incorporated;U-Vend,Inc.;Apollo Medical Holdings, Inc.;BioCorRx, Inc.;Intrexon Corporation;SSP;Royal Philips;New Generation Consumer Group, Inc.;Midrex Technologies, Inc.;RFMW Ltd.;Shenandoah Telecommunications Co;Medical Marijuana, Inc.;University of Colorado;LinnCo, LLC;Jiangsu Hengrui Medicine Co., Ltd.;Legacy Education Alliance, Inc.;Tekmira Pharmaceuticals Corporation;Diamondback Energy, Inc.;Sprott Physical Gold Trust;Sprott Physical Silver Trust;LinnCo, LLC ;Pascack Bancorp, Inc.;National Charity League, Inc., Glendale Chapter;Windstream ;Diamondback Energy, Inc.;Acasti Pharma Inc.;Rose Rock Midstream L.P.;SemGroup Corporation;Sprott Physical Gold Trust;Sprott Physical Silver Trust;New Penn;Reddaway;Holland;Merck;Genome Compiler Corp.;Shenandoah Telecommunications Co;Rethink Robotics;New Penn;Reddaway;Holland;Cancer Genetics, Inc.;Apollo Medical Holdings, Orbital Tracking;Zimbra;Visible Alpha;Immuron Limited;Lattice Incorporated ;Legacy Education Alliance, Inc.;LinnCo, LLC ;STEMCELL Technologies;State Investors Bancorp, Inc.;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Blyth, Inc.;Shared-Use Mobility Center;LinnCo, LLC;LinnCo, LLC ;Sprott Physical Gold Trust;Sprott Physical Silver Trust;Reddaway, Holland;American Water Works;Apollo Medical Holdings;A.H. Belo;Global Brands Group Holding Limited;Sprott Physical Gold Trust;Sprott Physical Silver Trust
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EXTON, Pa. and GERMANTOWN, Md., Oct. 08, 2015 (GLOBE NEWSWIRE) -- Fibrocell Science, Inc., (NASDAQ:FCSC), an autologous cell and gene therapy company focused on developing first-in-class treatments for rare and serious skin and connective tissue diseases with high unmet needs, and Intrexon Corporation (NYSE:XON), a leader in synthetic biology, today announced that a poster entitled “Pre-Clinical Development of a Genetically-Modified Human Dermal Fibroblast (FCX-007) for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)” will be presented at the American Society of Human Genetics Annual Meeting from October 6-10, 2015 in Baltimore, Maryland. The poster contains additional details of the previously reported positive in vivo pre-clinical data for FCX-007, Fibrocell’s orphan gene-therapy product candidate for the treatment of RDEB.
RDEB is caused by a mutation of the COL7A1 gene—the gene which encodes for type VII collagen (COL7), a protein that forms anchoring fibrils to hold together the layers of skin. Without these fibrils, skin layers separate causing severe blistering, open wounds and scarring in response to any kind of friction, including normal daily activities like rubbing or scratching.
In this in vivo pre-clinical study, FCX-007 was evaluated for toxicology and biological proof-of-concept in RDEB and normal human skin xenografts implanted onto severe combined immunodeficiency (SCID) mice. Toxicology results for FCX-007 showed at two- and six-weeks post-administration:
No test article-related findings; No tumors in the skin grafts or other organs; No statistical changes in blood chemistry; and No apparent systemic distribution of the vector. In addition, data supporting the biological proof-of-concept indicated FCX-007 cells in a human skin xenograft model expressed COL7 that localized to the basement membrane zone (BMZ) where anchoring fibrils are formed.
The poster will be available in the “Publications” section of Fibrocell’s website at: http://www.fibrocellscience.com/technology/publications/ .
About FCX-007
FCX-007 is Fibrocell's novel gene-therapy product candidate for the treatment of recessive dystrophic epidermolysis bullosa (RDEB), a congenital and progressive orphan skin disease caused by the deficiency of the protein type VII collagen (COL7). FCX-007 is a genetically-modified autologous fibroblast that encodes COL7 and is being developed in collaboration with Intrexon. By genetically modifying autologous fibroblasts, ex vivo , to produce COL7, culturing them and then treating blisters and wounds locally via injection, FCX-007 offers the potential to address the underlying cause of the disease by providing high levels of COL7 directly to the affected areas, thereby avoiding systemic treatment.
About Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Recessive dystrophic epidermolysis bullosa (RDEB) is the most severe form of dystrophic epidermolysis bullosa (DEB), a congenital, progressive, devastatingly painful and debilitating genetic disorder that often leads to death. RDEB is caused by a mutation of the COL7A1 gene, the gene which encodes for type VII collagen, a protein that forms anchoring fibrils. Anchoring fibrils hold together the layers of skin, and without them, skin layers separate causing severe blistering, open wounds and scarring in response to any kind of friction, including normal daily activities like rubbing or scratching. Children who inherit the condition are often called "butterfly children" because their skin is as fragile as a butterfly's wings. We estimate there are approximately 1,100 – 2,500 RDEB patients in the U.S. Currently, treatments for RDEB address only the sequelae, including daily bandaging, hydrogel dressings, antibiotics, feeding tubes and surgeries.
About Fibrocell Science, Inc.
Fibrocell Science, Inc. (NASDAQ:FCSC) is an autologous cell and gene therapy company primarily focused on developing first-in-class treatments for rare and serious skin and connective tissue diseases with high unmet medical needs. Fibrocell’s most advanced product candidate, azficel-T, uses its proprietary autologous fibroblast technology and is in a Phase II clinical trial for the treatment of chronic dysphonia resulting from vocal cord scarring. In collaboration with Intrexon Corporation (NYSE:XON), a leader in synthetic biology, Fibrocell is also developing gene therapies for skin diseases using gene-modified autologous fibroblasts. Fibrocell is in pre-clinical development of FCX-007, its orphan gene-therapy product candidate, for the treatment of recessive dystrophic epidermolysis bullosa (RDEB). Fibrocell is also in pre-clinical development of FCX-013, its second gene-therapy product candidate, for the treatment of linear scleroderma. For more information, visit fibrocell.com .
About Intrexon Corporation
Intrexon Corporation (NYSE:XON) is Powering the Bioindustrial Revolution with Better DNA™ to create biologically-based products that improve the quality of life and the health of the planet. The Company’s integrated technology suite provides its partners across diverse markets with industrial-scale design and development of complex biological systems delivering unprecedented control, quality, function, and performance of living cells. We call our synthetic biology approach Better DNA® , and we invite you to discover more at www.dna.com .
Fibrocell Forward-Looking Statements
This press release contains, and our officers and representatives may from time to time make, statements that are “forward-looking statements” within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995. All statements that are not historical facts are hereby identified as forward-looking statements and include, among others, statements relating to our development plans and timing; the potential for FCX-007 to be a first-in-class treatment for RDEB; and the potential advantages of our product candidates.
Forward-looking statements are based upon management's current expectations, intentions and beliefs and are subject to a number of risks, uncertainties, assumptions and other factors that could cause actual results and events to differ materially and adversely from those indicated by such forward-looking statements including, among others: our ability to successfully complete the additional toxicology study requested by the FDA for FCX-007 and to adequately address the FDA's other feedback relating to our IND for FCX-007; our ability to obtain FDA approval to commence the planned Phase I/II trial for FCX-007; varying interpretation of pre-clinical data; our ability to maintain our collaboration with Intrexon Corporation; and the risks, uncertainties and other factors discussed under the caption "Item 1A. Risk Factors" in our most recent Form 10-K and Form 10-Q filings, as well as discussions of potential risks, uncertainties and other important factors in our subsequent filings with the Securities and Exchange Commission. As a result, you are cautioned not to place undue reliance on any forward-looking statements. While we may update certain forward-looking statements from time to time, we specifically disclaim any obligation to do so, whether as a result of new information, future developments or otherwise.
Intrexon Forward-Looking Statements
Some of the statements made in this press release are forward-looking statements. These forward-looking statements are based upon our current expectations and projections about future events and generally relate to our plans, objectives and expectations for the development of our business. Although management believes that the plans and objectives reflected in or suggested by these forward-looking statements are reasonable, all forward-looking statements involve risks and uncertainties and actual future results may be materially different from the plans, objectives and expectations expressed in this press release.
Investor & Media Relations Contact:
Karen Casey
Fibrocell Science, Inc.
Tel: +1 (484) 713-6133
kcasey@fibrocellscience.com
Investor Contact:
Christopher Basta
Vice President, Investor Relations
Intrexon Corporation
Tel: +1 (561) 410-7052
Investors@intrexon.com