Medivir announces that development of the HCV nucleotide polymerase inhibitor AL-704 was terminated by Janssen


Stockholm, Sweden — Medivir AB (Nasdaq Stockholm: MVIR) today announces that the
development of AL-704 (also known as JNJ-54257099) has been terminated following
completion of phase I clinical studies conducted by Alios Biopharma Inc., one of
the Janssen Pharmaceutical Companies. These studies demonstrated that AL-704 was
safe, well tolerated and had acceptable pharmacokinetic properties. However its
clinical antiviral activity in persons infected with HCV genotype 1 was
insufficient to justify further clinical studies. No further compounds arising
from Medivir’s license agreement with Janssen on HCV NS5B polymerase inhibitors
are expected to be progressed into clinical studies, and therefore no further
revenues from this agreement will be received.

Termination of this project does not affect the MIV-802 project, which is wholly
owned by Medivir, nor any of the products or compounds in other partnerships
with Janssen.

For further information, please contact:
Ola Burmark, CFO Medivir AB, mobile: +46 (0) 725 480 580
Richard Bethell, EVP Discovery Research Medivir AB, mobile: +46 (0) 727 043 211
Medivir is required under the Securities Markets Act to make the information in
this press release public.
The information was submitted for publication at 8.30 CET on 21 December 2015.

About Medivir
Medivir is a research based pharmaceutical company with a research focus on
infectious diseases and oncology. We have a leading competence within protease
inhibitor design and nucleotide/nucleoside science and we are dedicated to
develop innovative pharmaceuticals that meet great unmet medical need. Our
commercial organization provides a growing portfolio of specialty care
pharmaceuticals on the Nordic market. Medivir is listed on the Nasdaq Stockholm
Mid Cap List.

Attachments

12218118.pdf