Invitation to Roche's live audio webcast on data presented at AAN 2019 - 13 May 2019

We are pleased to invite investors and analysts to participate in a live audio webcast and conference call on Monday, 13 May 2019, highlighting Roche data presented at the American Academy of Neurology (AAN) Annual Meeting (4-10 May 2019) in Philadelphia, United States. We would like to invite all interested parties to dial in as outlined below: 17:00 - 18:15 CEST / 16:00 - 17:15  BST 11:00 am - 12:15 pm EDT / 8:00 - 9:15 am PDT Audio webcast and conference call will start with presentations followed by a Q&A session (live access to the speakers). The live audio webcast can be accessed via ir.roche.com. In order to receive your personal dial-in details and expedite your access to the conference call, please pre-register under this link.  If you have not pre-registered, please find the dial-in numbers below, we recommend you to dial in to the conference 10-15 min prior to the scheduled start. +41 (0) 58 310 5000 (Europe and ROW) +44 (0) 207 107 0613 (UK) +1 (1) 631 570 5613 (USA Toll Free) Presentation slides will be posted on the Roche IR website click here. A replay of the webcast will be available via ir.roche.com.

Best regards, Karl Mahler Head of Investor Relations	Gerard Tobin Investor Relations Officer
Roche Investor Relations
Dr. Karl Mahler Phone: +41 61 68-78503 e-mail: karl.mahler@roche.com	Jon Kaspar Bayard Phone: +41 61 68-83894 e-mail: jon_kaspar.bayard@roche.com
Dr. Sabine Borngräber Phone: +41 61 68-88027 e-mail: sabine.borngraeber@roche.com	Dr. Bruno Eschli Phone: +41 61 68-75284 e-mail: bruno.eschli@roche.com
Dr. Birgit Masjost Phone: +41 61 68-84814 e-mail: birgit.masjost@roche.com	Dr. Gerard Tobin Phone: +41 61 68-72942 e-mail: gerard.tobin@roche.com
Investor Relations North America
Loren Kalm Phone: +1 650 225 3217 e-mail: kalm.loren@gene.com	Dr. Lisa Tuomi Phone: +1 650 467 8737 e-mail: tuomi.lisa@gene.com