The zoomed in area from image 1 allows a deeper analysis of specified ‘hotspots’. Different colors represent different cell types and biomarkers e.g., PD-1, PD-L1 (checkpoint targets in pink and red respectively), cytotoxic T cells (a type of immune cell, in yellow), regulatory T cells (in orange), macrophages (another type of immune cell, in green), and tumor cells (in cyan). The cellular composition and distribution reveals immune engagement with the tumor, evidenced by the immune cells (in yellow, green and orange) infiltrating the tumor areas (in cyan).
The zoomed in area from image 1 allows a deeper analysis of specified ‘hotspots’. Different colors represent different cell types and biomarkers e.g., PD-1, PD-L1 (checkpoint targets in pink and red respectively), cytotoxic T cells (a type of immune cell, in yellow), regulatory T cells (in orange), macrophages (another type of immune cell, in green), and tumor cells (in cyan). The cellular composition and distribution reveals immune engagement with the tumor, evidenced by the immune cells (in yellow, green and orange) infiltrating the tumor areas (in cyan).