The Tonks lab studied PTP1B inhibition in a mouse model of Alzheimer’s disease. When PTP1B was deleted, as shown in the bottom row, the brain’s immune cells (green) were better at engulfing harmful amyloid-β plaques (grey), as shown in the left column.
The Tonks lab studied PTP1B inhibition in a mouse model of Alzheimer’s disease. When PTP1B was deleted, as shown in the bottom row, the brain’s immune cells (green) were better at engulfing harmful amyloid-β plaques (grey), as shown in the left column.