Figure. Interim Rotarod (left) and qMR (EchoMRI) fat-mass (right) results in super-aged male rats (approximately 24 to 26 months old at enrollment) treated with vehicle or PTC-2105 0.5 or 12.5 mg/kg SC once weekly. Values are mean ± SEM percent change from each animal’s own baseline; n per group as shown. Week-16 Rotarod data are from the oldest cohort only. p values: Welch’s t-test vs. vehicle.
Figure. Interim Rotarod (left) and qMR (EchoMRI) fat-mass (right) results in super-aged male rats (approximately 24 to 26 months old at enrollment) treated with vehicle or PTC-2105 0.5 or 12.5 mg/kg SC once weekly. Values are mean ± SEM percent change from each animal’s own baseline; n per group as shown. Week-16 Rotarod data are from the oldest cohort only. p values: Welch’s t-test vs. vehicle.