(A) Illustration of the extracellular Perineural network (PNN), highlighted in green. (B) Immunohistology of one protein in the PNN in differentiated neuronal culture demonstrate that the new treatment on human neuronal culture successfully degraded the PNN. (C) Quantification of one PNN building block protein that was successfully inhibited by the new treatment.
(A) Illustration of the extracellular Perineural network (PNN), highlighted in green. (B) Immunohistology of one protein in the PNN in differentiated neuronal culture demonstrate that the new treatment on human neuronal culture successfully degraded the PNN. (C) Quantification of one PNN building block protein that was successfully inhibited by the new treatment.