A - DTI tracts images of PBS (1,2) and ExoPTEN x15 (3,4) treated spinal cords in ventral (1,3) and lateral (2,4) views. Rostral side is to the left and caudal to the right. Dashed white line represents the approximate compression area. B – normalized FA values. A significant differences were shown between ExoPTEN x15 treated rats and control PBS treated rats ( ****p value < 0.0001, paired t-test). C – normalized MD values . A significant differences were shown between ExoPTEN x15 treated rats and control PBS treated rats ( ***p value = 0.0002, paired t-test).
A - DTI tracts images of PBS (1,2) and ExoPTEN x15 (3,4) treated spinal cords in ventral (1,3) and lateral (2,4) views. Rostral side is to the left and caudal to the right. Dashed white line represents the approximate compression area. B – normalized FA values. A significant differences were shown between ExoPTEN x15 treated rats and control PBS treated rats ( ****p value < 0.0001, paired t-test). C – normalized MD values . A significant differences were shown between ExoPTEN x15 treated rats and control PBS treated rats ( ***p value = 0.0002, paired t-test).