Burlingame, CA, Dec. 15, 2025 (GLOBE NEWSWIRE) -- The Global Gene Expression Market is estimated to be valued at USD 16.56 Bn in 2025 and is expected to reach USD 23.61 Bn by 2032, exhibiting a compound annual growth rate (CAGR) of 5.2% from 2025 to 2032. This growth is fueled by rising investments in genomics research, continuous advancements in sequencing technologies, and the growing demand for personalized medicine. Together, these factors are accelerating the adoption of gene expression analysis across clinical and research environments worldwide.
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Global Gene Expression Market Key Takeaways
Instruments like PCR systems, next-generation sequencing systems, and microarray scanners are expected to account for 48.1% of the market share in 2025.
Drug discovery and development segment leads within the application segment with a market share of 45.6% in 2025, owing to need for personalized medicine and therapeutic research.
DNA microarray technology segment is slated to account for 32.4% of the gene expression industry in 2025.
North America is expected to lead the global gene expression industry with a share of 39.3% in 2025, followed by Asia Pacific region at 23.4%.
Rising Demand for Personalized Medicine Drives Gene Expression Market
The growing need for customized treatments is driving gene expression market, as healthcare providers adopt transcriptomics analysis to understand patient-specific gene activity. By using precise gene profiling technologies, researchers can examine DNA expression to identify disease susceptibility, therapeutic responses, and biomarkers, enhancing treatment efficacy. These applications will likely boost gene expression market size and influence investment in innovative healthcare solutions.
Targeted therapies, especially in oncology, rely on patient-specific genetic data, which is impacting gene expression market dynamics globally. Advanced RNA sequencing (RNA-Seq) and gene regulation research tools are enabling clinicians to design therapies with higher efficacy and fewer side effects. The continued focus on personalized medicine is expanding the gene expression market and shaping the future.
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High Costs Limiting Adoption in Gene Expression Market
The increasing costs of sophisticated tools such as the RNA sequencing (RNA-Seq) platforms and gene regulation study tools are limiting gene expression market. Smaller laboratories and other research institutes find it difficult to afford high-end gene profiling technologies, limiting the overall gene expression market size. These costs, as well as maintenance and skilled labor, also affect wider participation, which limits innovation in transcriptomics analysis.
High pricing poses the two biggest challenges to gene expression market. First, it is reducing the inclusivity in research, limiting information from various study contexts, which can impact the gene expression market trends. Second, there are financial limitations to the speed of transformation of the results into practical applications, affecting gene expression market value. Collaborative funding, low-cost technologies, and novel solutions are necessary to propel gene expression market forward and to maintain the growth in the field of genetics and personalized medicine.
Cost-Effective Technologies Driving Single-Cell Gene Profiling
The development of high-throughput gene profiling technologies is accelerating growth in the gene expression market demand, providing researchers with new insights into cellular heterogeneity. Advanced transcriptomics analysis tools allow the study of individual gene expression patterns, which is especially transformative in cancer research and personalized treatment planning. These innovations are expanding gene expression market by enabling precise identification of cellular differences in heterogeneous populations.
Single-cell technologies also support a better understanding of disease mechanisms and gene regulation. Improved RNA sequencing (RNA-Seq) solutions help identify rare cell subpopulations and disease-specific biomarkers, enhancing therapeutic precision. Overall, these tools are driving gene expression market value, supporting pharmaceutical companies in discovering novel drug targets and evaluating efficacy.
Emerging Trends in Gene Expression Market
The adoption of RNA sequencing platforms is growing across research institutions. This trend is driving gene expression market demand by making high-throughput experiments possible. It also supports the development of personalized medicine and targeted therapies.
Growing use of gene profiling technologies is affecting laboratory practices. These advancements are influencing gene expression market by enabling more accurate analysis of genes. The tools facilitate early disease detection and new therapeutic research.
Advancements in transcriptomics analysis are aiding scientists in gaining insights into the intricacies of cellular functions. This development has a positive impact on the gene expression market, as it allows for better data interpretation. It also contributes to better research on gene regulation and cellular mechanisms.
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Analyst’s View
“The global gene expression market is expected to experience significant growth as the demand for personalized medicine and advanced research tools rises. Companies offering innovative gene profiling technologies, RNA sequencing (RNA-Seq) market platforms, and transcriptomics analysis solutions are well-positioned to capture market share. Continuous developments in high-throughput sequencing, bioinformatics, and functional genomics are likely to drive gene expression market demand further,” said a senior analyst at CMI.
Competitor Insights
Key players in gene expression market report include:
- Thermo Fisher Scientific Inc
- Agilent Technologies Inc
- Illumina Inc
- QIAGEN N.V
- Bio-Rad Laboratories Inc
- Roche Diagnostics
- PerkinElmer Inc
- Takara Bio Inc
- Promega Corporation
- GE Healthcare
- Pacific Biosciences of California Inc
- Oxford Nanopore Technologies
- Fluidigm Corporation
- Lonza Group Ltd
- Eurofins Genomics
Recent Development
In January 2023, QIAGEN Digital Insights introduced the CLC Genomics Workbench Premium, a platform designed to speed up next-generation sequencing data analysis and overcome major processing bottlenecks.
In August 2024, scientists at Northwestern University discovered how RNA interactions with the TOP1 enzyme to regulate DNA during transcription, offering insights that may support new cancer therapy development.
Market Segmentation
Product Type Insights (Revenue, USD Bn, 2020 - 2032)
- Instruments (PCR Systems, Next-Generation Sequencing Systems, Microarray Scanners, etc.)
- Consumables and Reagents (Kits, Assays and Probes, DNA Chips etc.)
- Software and Services
Application Insights (Revenue, USD Bn, 2020 - 2032)
- Drug Discovery and Development
- Clinical Diagnostics
- Research and Development
Technology Insights (Revenue, USD Bn, 2020 - 2032)
- DNA Microarray
- PCR-Based (qPCR, RT-PCR)
- RNA Sequencing (RNA-Seq)
- Northern Blotting
- Next-Generation Sequencing (NGS)
- Serial Analysis of Gene Expression (SAGE)
Workflow Stage Insights (Revenue, USD Bn, 2020 - 2032)
- Sample Collection and Preparation
- RNA Isolation and Purification
- cDNA Synthesis and Amplification
- Detection and Quantification
- Data Analysis and Interpretation
Sample Type Insights (Revenue, USD Bn, 2020 - 2032)
- Human Samples
- Animal Samples
- Microbial Samples
End User Insights (Revenue, USD Bn, 2020 - 2032)
- Academic and Research Institutes
- Pharmaceutical and Biotechnology Companies
- Contract Research Organizations (CROs)
- Hospitals and Clinical Laboratories
Regional Insights (Revenue, USD Bn, 2020 - 2032)
- North America
- U.S.
- Canada
- Latin America
- Brazil
- Argentina
- Mexico
- Rest of Latin America
- Europe
- Germany
- U.K.
- Spain
- France
- Italy
- Russia
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- GCC Countries
- Israel
- Rest of Middle East
- Africa
- South Africa
- North Africa
- Central Africa
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