SAN DIEGO, Sept. 28, 2015 (GLOBE NEWSWIRE) -- BioNano Genomics, Inc., the leader in physical genome mapping, today announced that it will present five posters supporting the utility of its Irys® System in human genome research at the upcoming 2015 American Society of Human Genetics (ASHG) Annual Meeting being held October 6 – 10, 2015 at the Baltimore Convention Center in Baltimore, Maryland.
Erik Holmlin, Ph.D., President and Chief Executive Officer of BioNano Genomics, commented, "We are excited to present findings from a host of different studies that underscore the utility of the Irys System for next generation mapping. The Irys System is proving to be an essential tool for genome analysis because it provides a comprehensive view of genomic architecture. The findings reported in these studies show our ability to provide independent detection of known structural variations and to identify novel large complex structural variations that are beyond the limits of next generation sequencing. We also demonstrate the compatibility of next generation mapping with sequencing to produce highly contiguous hybrid scaffolds that reveal chromosome architecture at a reduced time and cost compared to traditional methods of generating complete genome assemblies."
The five accepted posters will be presented during multiple sessions throughout the meeting; additional details include:
- Poster 1832T: Resizing N-Base Gaps in the Human Reference Genome
| First / Presenting Author: | Zeljko Dzakula, Ph.D. |
| Poster Session: | Bioinformatics and Genomic Technology |
| Date, Time: | Thursday Oct 8th, 12:00 – 1:00 p.m. ET |
| Location: | Exhibit Hall, Level 1 |
- Poster 2496F: De Novo Assembly of the Genome-in-a-Bottle Reference Ashkenazi Trio, Structural Variation Discovery and Comparison with Other Individuals by Genome Mapping
| First / Presenting Author: | Alex Hastie, Ph.D. |
| Poster Session: | Cytogenetics |
| Date, Time: | Friday Oct 9th, 11:45 a.m. – 12:45 p.m. ET |
| Location: | Exhibit Hall, Level 1 |
- Poster 3118T: Mapping the "Dark Matter" of the Genome – Complex Structural Variations and Towards True Contiguity of De Novo Assembly with NanoChannel Technology
| First / Presenting Author: | Han Cao, Ph.D. |
| Poster Session: | Genome structure, variation and function |
| Date, Time: | Thursday Oct 8th, 12:00 – 1:00 p.m. ET |
| Location: | Exhibit Hall, Level 1 |
- Poster 2721W: Towards Understanding the Genomic Architecture of Cancer Genomes
| First / Presenting Author: | Ernest Lam, Ph.D. |
| Poster Session: | Cancer Genetics |
| Date, Time: | Wednesday Oct 7th, 5:00 – 6:00 p.m. ET |
| Location: | Exhibit Hall, Level 1 |
- Poster 1632F: Integrated Genome Mapping in NanoChannel Arrays and Sequencing for Better Human Genome Assembly and Structural Variation Detection
| First / Presenting Author: | A.W.C. Pang, Ph.D. |
| Poster Session: | Bioinformatics and Genomic Technology |
| Date, Time: | Friday Oct 9th, 11:45 a.m. – 12:45 p.m. ET |
| Location: | Exhibit Hall, Level 1 |
The Irys System can provide valuable insights about the biology of the genome based on information about the order, orientation, arrangement, and interaction of genomic components. Irys also works as a complement to read-based sequencing technologies to yield long-range genomic information, identify structural variations and bridge repeats and other complex elements in the genome. The Irys System uses IrysPrep Reagents to extract and label long DNA molecules and the IrysView and IrysSolve software to provide powerful de novo assemblies and analysis of the genome.
About BioNano Genomics
BioNano Genomics, Inc., the leader in next generation mapping, provides customers with genome analysis tools that advance human, plant, and animal genomics and accelerate the development of clinical diagnostics. The Company's Irys® System uses NanoChannel arrays integrated within the IrysChip® to image genomes at the single molecule level with average single molecule lengths of about 350,000 base pairs, which leads the industry. The long-range genomic information obtained with the Irys System spans large, complex DNA repeats, which are the primary cause of inaccurate and incomplete genome assembly. On its own, next generation mapping with the Irys System enables detection of structural variants, which are increasingly associated with human disease as well as complex traits in plants and animals. As a companion to next generation sequencing, next generation mapping with the Irys System integrates with sequence assemblies to create contiguous hybrid scaffolds that reveal the highly-informative native structure of the chromosome. Only BioNano Genomics provides long-range genomic information with the cost-efficiency and throughput to keep up with advances in next generation sequencing. The Irys System has been adopted by a growing number of leading institutions around the world, including: National Cancer Institute (NCI), National Institutes of Health (NIH), Wellcome Trust Sanger Institute, Broad Institute of MIT and Harvard, BGI, Garvan Institute, Salk Institute, and McDonnell Genome Institute of Washington University. Investors in the Company include Battelle Ventures, Domain Associates, Legend Capital, Novartis Venture Fund, Federated Kaufmann, Monashee Investment Management, and Gund Investment Corporation.
For more information, please visit us at www.BioNanoGenomics.com.
Notes: BioNano Genomics is a trademark of BioNano Genomics, Inc. Any other names of actual companies, organizations, entities, products or services may be the trademarks of their respective owners.