Cell-based Assays Market Size to Hit Around USD 42.32 BN by 2032

The global cell-based assay market size was surpassed at USD 17.83 billion in 2022 and it is estimated to hit around USD 42.32 billion by 2032, growing at a CAGR of 9.03% between 2023 and 2032.


Ottawa, July 03, 2023 (GLOBE NEWSWIRE) -- As per Precedence Research, the U.S. cell-based assays market size was estimated at USD 6.7 billion in 2022. The global cell-based assay market growth is driven by rising investments in R&D for drug discovery, increasing preference for cell-based assays in drug discovery, innovative product launches by prominent market players, increasing government expenditure in the healthcare sector, the rising need for toxicity screening in drugs, the increasing demand for efficient treatment for rare diseases, rapid growth in biotechnology & biopharmaceutical industries, and increasing demand for novel drugs for treating chronic disorders.

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Market Overview

A cell-based assay is used in life science research and drug discovery for screening purposes. Cell-based assays offer a wealth of information and are crucial tools in drug discovery applications. Cell-based assay defines as a method of analysis of living cells on the basis of various parameters. Cell-based assays are used to assess various functional and biochemical effects, such as cell viability, cytotoxicity, proliferation, apoptosis, reporter gene activity, receptor occupancy, signal transduction, receptor binding, complement dependent cytotoxicity (CDC), and others. Cell-based assays are used by pharmaceutical companies, contract research organizations (CROs), academic research institutes, and others. Cell-based assays are widely used in high-throughput screening formats. Cell-based assays and analysis play a vital role in various stages of the drug development process such as early discovery, pre-clinical, clinical, and other stages.

Cell-based assays help in various ways such as lead candidate selection, drug efficacy, and providing invaluable information about the therapeutic mechanism of action (MOA). The innovative advances in cell-based assay technology have permitted researchers to use this method for drug discovery and toxicology studies. Cell-based assays are used to identify an impact or event within a cell, study gene, protein, or whole cellular functions and the regulatory mechanisms governing them, and screen for potential inducers or inhibitors of biological processes in drug development. Additionally, the market has grown as a result of the increasing prevalence of chronic disorders such as cardiovascular, cancer, infectious diseases, diabetes, neurological disorders, and others. Furthermore, technological advancements in cell-based methodologies are anticipated to drive the cell-based assay market in the coming years.

Regional Insights

North America accounted for the larger market share 42% in 2022, owing to the increasing prevalence of chronic diseases such as cancer, cardiovascular, cancer, diabetes, neurological disorders, osteoarthritis, diabetes, and others, increasing R&D expenditure, high adoption of cell-based assays, the presence of well-established healthcare infrastructure, rising drug discovery activities, innovative product launches by key market players is anticipated to fuel the demand for cell-based assays for newer drug discoveries, making it a crucial factor for the growth of the market in the region.

On the other hand, the Asia Pacific market is expected to grow at a significant CAGR during the forecast period due to the rise in healthcare expenditure, increase in cell-based applications in drug discovery, and increasing research and development investment by the government.

Report Highlights

  • By technology, in 2022, the high-throughput screening segment is predicted to hold the largest market share. High-throughput screening methods are extensively employed in pharmaceutical firms, HTS is the use of an automated tool to rapidly test thousands to millions of samples for biological activity at the model organism, cellular, pathway, or molecular level. High throughput screening is a drug discovery process that allows a biochemical or cellular event to be quickly tested against chemical entities hundreds of thousands of times.
  • By Application, in 2022, the drug discovery segment is expected to dominate the global cell-based assays market with 41% revenue share and is expected to retain its dominance during the forecast period owing to an increasing number of CROs providing drug discovery services, the launch of new drugs for the treatment of rare diseases, and increasing prevalence of infectious diseases, cardiovascular disorders, cancer, diabetes, genetic disorders, neurological disorder, and others.
  • By End User, the biotechnology & pharmaceutical firms segment has accounted 52% revenue share in 2022. Cell-based assays are widely used by biotechnology & pharmaceutical companies. Cell-based assays are very helpful in pharmaceutical firms for identifying how environmental stimuli or pharmacological substances affect cellular activity. The growth of this segment is attributed to the wide adoption of strategic approaches such as partnership or collaboration to develop drug candidates, a rapid rise in the number of drug discovery activities, and the increased funding for research & development activities.

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Scope of the report

CoverageDetails
Market Size in 2030USD 35.6 billion
CAGR9.03% from 2023 to 2032
North America Market Share42% in 2022
Europe Market Share38% in 2022
Asia Pacific Market Share23% in 2022
Key PlayersDanaher Corporation, Promega Corporation, F. Hoffmann-La Roche AG, Lonza Group AG, Charles River Laboratories International, Inc., Menarini Silicon Biosystems, Inc., Bio-Rad Laboratories, Inc., Macrogen Inc, DiscoverX Corporation, Corning Inc., Becton, Dickinson and Company, Thermo Fisher Scientific Inc., Perkinelmer, Inc., Biognosys, Cell Signaling Technology, Inc., Merck KGaA, Lebermuth, Inc., Eurofins DiscoverX Products, and Others

Market Dynamics

Drivers

Increase in drug discoveries and approvals

The researchers continuously work towards discovering next-generation drugs to treat patients with chronic diseases. Cell-based assays are extensively used in the drug discovery process for validating potential drug candidates. In recent years, pharmaceutical firms have discovered an increasing number of drugs. Cell-based assays speed up and enhance drug development, enabling the speedy and effective commercialization of therapeutics. In 2021, the CDER approved about 50 novel therapeutics.

Increasing prevalence of the chronic diseases

The increasing prevalence of chronic disorders such as cardiovascular, cancer, diabetes, neurological disorders, and others is expected to boost the cell-based assay market growth during the forecast period. As per CDC, 6 in 10 Americans suffer from one or other chronic disorders such as cardiovascular, cancer, stroke, diabetes, and others. These and other chronic disorders are the leading causes of death and disability in America, and also a crucial driver of health care costs. Therefore, with increasing cases of chronic disorders across the globe, the demand for effective treatment is growing which is anticipated to fuel the growth of the cell-based assay market in the coming years.

Restraint

High maintenance cost and initial investment for instruments 

The initial investment for instruments is projected to impede revenue growth of the global cell-based assay market. Technology advancement including high-content screening and high-throughput screening, the costs of these technologies are quite high which results in slow adoption in many developing countries. In addition, the high maintenance cost is likely to limit the expansion of the global cell-based assay market during the forecast period.

Opportunities

Growing Biotechnology & Biopharmaceutical companies

The increase in the number of Biotechnology & Biopharmaceutical companies is projected to offer lucrative growth opportunities for the market growth. Biotechnology & Biopharmaceutical companies are rapidly gaining popularity. Biotechnology & Biopharmaceutical companies increasingly use cell-based assays. As a part of their lead discovery and optimization processes for drug development, the Biotechnology & Biopharmaceutical companies are employing cell-based assays.

Recent Developments:

  • In June 2021, Danaher Corporation announced that Danaher has entered into a definitive agreement to acquire Aldevron company, for a cash purchase price of nearly USD 9.6 billion. This acquisition is expected to lead the field of development of genomic medicine.
  • In January 2021, Thermo Fisher Scientific completed its acquisition of Phitonex, a North Carolina-based company that has created a spectral dye platform for high-resolution biology applications. Phitonex's Phiton platform is designed to accelerate cell therapy, immuno-oncology, and immunology research and development. The acquisition will help Thermo Fisher to provide greater flow cytometry and imaging multiplexing capabilities for protein and cell analysis research needs.
  • In May 2021, DILI 3D cell culture assay services using corning-qualified 3D PHH spheroid assay-ready plates launched by Visikol. Visikol is a contract research services company that emphasizes on speed up drug discovery and development through the use of its digital pathology, imaging, and advanced cell culture assay services

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Market Segmentation

By Type

  • Cell Viability Assay
  • Cytotoxicity Assay
  • Cell Death Assay
  • Cell Proliferation Assay
  • Others

By Products & Services

  • Reagents
  • Assay Kits
  • Cell Growth Assays
  • Reporter Gene Assays
  • Cell Death Assays
  • Second Messenger Assays
  • Microplates
  • Probes & Labels
  • Instruments & Software
  • Cell Lines
  • Primary Cell Lines
  • Stem Cell Lines
  • Immortalized Cell Lines

By Application

  • Basic Research
  • Drug Discovery
  • Other Applications

By Technology

  • Automated Handling
  • Flow Cytometry
  • Label-free Detection
  • High-throughput Screening
  • Others

By End-use

  • Pharmaceutical and Biotechnology Companies
  • Academic & Government Institutes
  • Contract Research Organizations

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

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