Turnstone Biologics to Present Preclinical Data for Selected Tumor-Infiltrating Lymphocyte (TIL) Therapy at Society for Immunotherapy of Cancer’s (SITC) 38th Annual Meeting


SAN DIEGO, Sept. 28, 2023 (GLOBE NEWSWIRE) -- Turnstone Biologics Corp. (“Turnstone” or the “Company”) (Nasdaq: TSBX), a clinical-stage biotechnology company developing new medicines to treat and cure solid tumors by pioneering a differentiated approach to tumor-infiltrating lymphocyte (TIL) therapy, today announced four posters reporting preclinical data for Turnstone’s Selected TIL therapies will be presented at the 38th Annual Meeting of the Society for Immunotherapy of Cancer (SITC). The SITC 38th Annual Meeting will be held from November 1-5, 2023, in San Diego, California.

The details of the posters are as follows:

In collaboration with Moffitt Cancer Center

TitleExpansion and Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes (TIL) from Metastatic Colorectal (CRC) and GI Cancers
AuthorsMatthew Beatty, Madeline Rodriguez-Valentin, MacLean Hall, Fatema Khambati, Amy Hall, Larissa Pikor, Timothy Langer, Barbara Sennino, Jamie Teer, Jason Fleming, Shari Pilon-Thomas
Presentation TypePoster
Session Date and TimeNovember 4, 2023: 9:00 AM - 8:30 PM PT
Abstract Number346

 

TitleEnhancing Directly Selected Tumor-Reactive TIL Function Through Genetic Modification
AuthorsEmily Carron, Sowbarnika Ratliff, April Fraley, Justin Rahman, Niloufar Khojandi, Bryant Thompson, Mathew Thayer, Christophe Pedros, Larissa Pikor, Barbara Sennino
Presentation TypePoster
Session Date and TimeNovember 4, 2023: 9:00 AM - 8:30 PM PT
Abstract Number350

 

In collaboration with Illumina, Inc.

TitleTumor Neoantigen Prioritization from Liquid Biopsy Whole Exome Sequencing for Selected Tumor-Infiltrating Lymphocyte Therapy
AuthorsUrminder Singh, Christian Laing, Jacob Gibson, Anna Kluew, Mahdi Golkaram, Sven Bilke, Larissa Pikor, Nathalie Brassard, Matthew Beatty, Doris Wiener, Brian Czerniecki, Shari Pilon-Thomas, Simon Turcotte, Li Liu, Stewart Abbot, Timothy Langer, Grace DeSantis, Michael Ciancanelli, Jeff Tsai
Presentation TypePoster
Session Date and TimeNovember 4, 2023: 9:00 AM - 8:30 PM PT
Abstract Number178


TitleTBio BFX 4101: A Neoantigen Prioritization Pipeline for Selected Tumor-Infiltrating Lymphocyte Therapy
AuthorsChristian Laing, Quanyuan He, Tony Collins, Meghan Verschoor, Chantal Martin, Stewart Abbot, Michael Ciancanelli
Presentation TypePoster
Session Date and TimeNovember 4, 2023: 9:00 AM - 8:30 PM PT
Abstract Number900


About Turnstone

Turnstone Biologics is a clinical-stage biotechnology company developing new medicines to treat and cure solid tumors by pioneering a differentiated approach to TIL therapy. Turnstone’s innovative TIL therapy is based upon the identification, selection, and expansion of the most potent tumor-reactive T cells, known as Selected TILs, and is designed to overcome the limitations of first-generation bulk TILs that have demonstrated objective responses only in limited tumor types. Turnstone’s most advanced program, TIDAL-01, is currently being evaluated in two Phase 1 studies in patients with melanoma, breast cancer and colorectal cancer, and the Company is also actively advancing its preclinical pipeline programs including TIDAL-02, its next Selected TIL program, and its TIDAL-01 and viral immunotherapy combination program. For additional information about Turnstone, please visit www.turnstonebio.com, and follow us on LinkedIn.

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Contact

Ahmed Aneizi
Investor Relations
Turnstone Biologics
(347) 897-5988
ahmed.aneizi@turnstonebio.com