United States Humanized Mice Model Research Report 2023: Markets, Competition, Forecast and Opportunities, 2018-2028

Dublin, Nov. 24, 2023 (GLOBE NEWSWIRE) -- The "United States Humanized Mice Model Market, Competition, Forecast and Opportunities, 2018-2028" report has been added to ResearchAndMarkets.com's offering.

United States Humanized Mice Model Market is anticipated to project steady growth rate to 2028

This groundbreaking technique serves as an indispensable tool in the field of biomedical research, specifically in the study of human diseases. By introducing human elements into mice, scientists gain the ability to closely observe and analyze disease progression, as well as assess the efficacy of potential treatments, all within a living organism.

This innovative approach not only provides valuable insights into the mechanisms underlying human diseases but also offers a means to test experimental therapies without the ethical concerns associated with human experimentation. Through the utilization of Humanized Mice Models, researchers are able to delve deeper into the complexities of human health and make significant strides towards improving medical treatments and interventions.

Increased Use in Oncology Research

The increased use of humanized mice models in oncology research is expected to boost their demand in the United States. This surge is attributed to the mouse models' exceptional ability to mimic human physiology and immune system responses, thus providing a valuable platform for cancer research.

Oncologists are using these models to study the diversity of human cancers, understand tumor progression, and explore potential treatment modalities. The rise in cancer cases nationwide further intensifies the need for innovative research tools, putting humanized mice models at the forefront. Additionally, advancements in genetic engineering techniques have improved the quality and diversity of these models, making them more appealing for complex cancer research.

With the United States being a global leader in medical research, the demand for these models is expected to grow. This surge is further amplified by increased funding for cancer research and the steady development of customized models for specific cancer types. Consequently, the utilization of humanized mice models in oncology research creates a robust demand in the United States, driving the market's growth.

Increased Preclinical Drug Testing

The demand for Humanized Mice Models in the United States is predicted to rise significantly due to an increase in preclinical drug testing. As drug discovery and development processes are becoming more complex, the need for reliable and predictive models is paramount.

Humanized Mice Models, with their human-like immune system responses, have proven to be invaluable tools in preclinical stages, especially in oncology, immunology, infectious diseases, and autoimmunity studies. They offer a robust platform for testing drug efficacy, safety, and pharmacokinetics before advancing to human trials. The growing prevalence of diseases, coupled with an upsurge in biotechnological and pharmaceutical R&D investments, is expected to drive the need for preclinical trials, subsequently fueling the demand for Humanized Mice Models.

Moreover, the recent FDA guidelines encouraging the adoption of such models for early toxicity and efficacy evaluation are likely to further stimulate the market growth. Consequently, as preclinical drug testing expands, the reliance on Humanized Mice Models is poised to increase, catering to the demand for more realistic and informative preclinical study outcomes.

Key Market Drivers

Increasing Need for Personalized Medicine

The escalating need for personalized medicine is predicted to surge the demand for humanized mice models in the United States. Personalized medicine, with its tailor-made approach, relies heavily on the concept of individual variability in genes, environment, and lifestyle.

The growth of personalized medicine therefore directly correlates with the increased need for humanized mice, reinforcing the crucial role these models play in medical research and development.

Advancement In Gene Editing Tools

The advancement in gene-editing tools, predominantly the CRISPR-Cas9 system, is expected to drive the demand for Humanized Mice Models (HMMs) in the United States significantly. HMMs have become invaluable in biomedical research for modeling human diseases, due to the genetic similarity between humans and mice.

Furthermore, the evolution of these technologies has also made it feasible to humanize mice with patient-specific cells, pushing personalized medicine forward. As these capabilities increase, so does the need for HMMs in cutting-edge biomedical research, driving their demand in the United States.

The backing of substantial federal research funding and the presence of major pharmaceutical and biotech companies in the U.S. will further compound this effect, emphasizing the role of gene-editing advancements in the increased demand for HMMs.

Increasing Number of Research Activities Involving Humanized Models

The growing number of research activities involving humanized models in the United States is projected to significantly fuel the demand for Humanized Mice Models. These models offer a unique platform for understanding human immunology, diseases, and therapeutic responses by replicating human-specific responses.

Furthermore, the ongoing R&D investments and government funding for biomedical research are expected to contribute to the increased adoption of these models. As the number of these research activities continues to rise in the United States, so too will the demand for Humanized Mice Models.

Increasing Number Of R&D Activities in Pharmaceutical & Biotechnology Companies

The pharmaceutical and biotechnology industries in the United States are witnessing an unprecedented surge in research and development (R&D) activities. This expansion is set to significantly drive demand for Humanized Mice Models (HMMs), an essential tool used in these sectors.

Key Market Challenges

High Costs Associated with Development of Humanized Mice Models

The high costs associated with the development of Humanized Mice Models (HMMs) may curtail their demand in the United States. Creating HMMs demands sophisticated biotechnological processes and highly skilled professionals, factors that contribute significantly to the overall cost.

As a result, the high development and maintenance costs associated with HMMs are expected to decrease their demand in the U.S., potentially slowing advancements in this critical area of medical research. The onus, then, is on both public and private sectors to address these cost issues, possibly through funding initiatives or cost-effective innovation, to maintain the momentum of research involving HMMs.

Stringent Regulations and Laws Formulated for The Ethical Use Of Animals

Stringent regulations and laws formulated for the ethical use of animals are expected to decrease the demand for humanized mice models in the United States. The public concern over animal welfare has led to the development and implementation of comprehensive legislation and guidelines that govern the use of animals in scientific research.

Additionally, public accountability and the potential reputational damage that can result from perceived unethical practices further contribute to the declining demand. Thus, the combination of regulatory constraints, advancing technologies, and public sentiment is likely to see a reduction in the use of humanized mice models within the United States.

Segmental Insights

Genetic Humanized Mice Model:

  • Genetic Humanized Mice Models are expected to dominate the US Humanized Mice Model Market.
  • They mimic the human immune system, facilitating accurate preclinical research and drug development.
  • Increasing use in therapeutic areas like oncology, immunology, and infectious diseases drives their adoption.
  • Genetic similarity to humans allows the study of specific genes and genetic variations.
  • Precision and relevance in modeling human biology make them invaluable in biomedical research.

Oncology Studies Application:

  • In the US Humanized Mice Model Market, Oncology Studies hold the largest market share.
  • These models are crucial in cancer research, providing insights into tumorigenesis, metastasis, and therapeutic interventions.
  • They enable the evaluation of immunotherapies, enhancing cancer treatment strategies.
  • The interaction between the immune system and cancer cells can be studied for identifying immunotherapeutic targets.
  • Oncology Studies segment is expected to drive advancements in cancer research and treatment.

Regional Insights (North-East US):

  • The North-East region of the US is set to dominate the Humanized Mice Model Market.
  • Robust research and development infrastructure with world-class academic institutions and cutting-edge laboratories.
  • Collaboration-friendly environment attracting top researchers and scientists.
  • High concentration of leading pharmaceutical and biotechnology companies fostering partnerships and collaborations.
  • Substantial government funding dedicated to advancing scientific discoveries and research.
  • Leading the way in preclinical research, therapeutic development, and biotech industry growth.

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the United States Humanized Mice Model Market.

  • Charles River Laboratories International, Inc.
  • The Jackson Laboratory
  • Taconic Biosciences Inc.
  • Hera BioLabs
  • Ingenious Targeting Laboratory Inc.
  • Champions Oncology, Inc.
  • Yecuris Corporation

Report Scope:

United States Humanized Mice Model Market, By Type:

  • Genetic Humanized Mice Model
  • Cell-based Humanized Mice Model

United States Humanized Mice Model Market, By Application:

  • Oncology Studies
  • Immunology and Inflammation Studies
  • Others

United States Humanized Mice Model Market, By End User:

  • Pharmaceutical & Biotechnology Companies
  • Academic & Research Institutes
  • Contract Research Organizations

United States Humanized Mice Model Market, By Region:

  • Northeast Region
  • Midwest Region
  • West Region
  • South Region

For more information about this report visit https://www.researchandmarkets.com/r/4wo8o7

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