Global Upstream Bioprocessing Market Projected to Reach $25 Billion by 2030 - Analysis by Product Type, Workflow, Usage Type, Mode, and Region

Dublin, March 20, 2024 (GLOBE NEWSWIRE) -- The "Upstream Bioprocessing Market Size and Forecast, Global and Regional Share, Trends, and Growth Opportunity Analysis" report has been added to's offering.

The global upstream bioprocessing market is on a steep trajectory of growth, with projections to reach a valuation of US$ 25.046 billion by 2030. This market, which stood at US$ 9.174 billion in 2022, is expected to flourish at a CAGR of 13.4% between 2022 and 2030.

The adoption of single-use bioreactors, growth of the biopharmaceutical sector, and robust outsourcing trends in bio-manufacturing drive the upstream bioprocessing market forward. With a focus on developments like the integration of Repligen Corporation's XCell ATF technology with Sartorius Biostat STR in September 2023, the market has been introduced to technological innovations enhancing process efficiency and adaptability.

Recent Technological Advancements in Upstream Bioprocessing

Innovative technological advancements in the sector, such as advanced cell culture systems and bioreactor designs, are revolutionizing upstream bioprocessing. The integration of automation, digitization, and analytical tools is shaping a new era of data-driven bioprocessing. This transformation opens up new opportunities for improved yields, quality, and efficient production of complex biological products.

Regulatory Challenges Facing the Upstream Bioprocessing Industry

Despite the optimistic outlook, the market faces regulatory hurdles that may encumber growth. Stringent regulations and the necessity for adherence to cGMP and GLP are highlighted as constraints. These challenges emphasize the need for compliance and high-quality standards in the bioprocessing industry.

Comprehensive Segment Analysis of the Upstream Bioprocessing Market

  • The market is segmented based on product type, workflow, usage type, and mode, with bioreactors/fermenters holding a significant market share in 2022.
  • Cell culture and cell separation workflows are identified as key market segments, with cell separation attracting considerable attention due to its critical role in bioprocessing.
  • Single-use technologies are influencing the market by offering benefits such as reduced contamination risk and operational flexibility, leading to a surge in their adoption.
  • In-house and outsourced manufacturing options provide diverse strategies for biopharmaceutical enterprises, with in-house manufacturing taking precedence in 2022 but outsourced services anticipated to grow rapidly.

Geographical Dominance and Growth Outlook

North America, particularly the US, dominates the upstream bioprocessing market landscape, with an impressive growth rate expected through 2030. Strategic initiatives such as BioMADE's commitment to addressing bioreactor research and Cytiva's launch of X-platform bioreactors are testaments to the region's pioneering status in bioprocessing innovations.

The Role of Key Market Players and Regulatory Bodies

The growth of the upstream bioprocessing market is also influenced by the active participation of key market players and guidance from regulatory bodies like the FDA and EMA. The emphasis on improving clinical trial outcomes and patient safety via increased R&D investments plays a crucial role in market growth, particularly in the US.

Key Attributes

Report AttributeDetails
No. of Pages210
Forecast Period2022-2030
Estimated Market Value (USD) in 2022$9.17 Billion
Forecasted Market Value (USD) by 2030$25.05 Billion
Compound Annual Growth Rate13.4%
Regions CoveredGlobal

A selection of companies mentioned in this report includes:

  • Thermo Fisher Scientific Inc
  • Esco Micro Pte. Ltd.
  • Cellexus International Ltd.
  • Sartorius AG
  • Danaher Corp.
  • Getinge AB
  • Merck KGaA
  • Corning Inc.
  • Entegris Inc.
  • PBS Biotech Inc.

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Upstream Bioprocessing Market

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