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Data presented at Kidney Week 2025 showed single subcutaneous administration of megalin-STRIKERs resulted in increased excretion of disease-related solute levels lasting for at least 2 months Dr....
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In vivo studies demonstrate robust and durable gene silencing across rodents and non-human primates Megalin-targeting ligand-siRNA conjugates (megalin-STRIKERs) deliver siRNAs to proximal tubular...