Results from in vitro Brain chip models demonstrate that: Treatment with aSyn fibrils disrupted vascular integrity of brain chip (blue) compared to untreated control (black); Concurrent pepinemab treatment significantly inhibited effects of aSyn (green closed squares); Delayed pepinemab treatment significantly reversed effects of aSyn (green open squares)
Results from in vitro Brain chip models demonstrate that: Treatment with aSyn fibrils disrupted vascular integrity of brain chip (blue) compared to untreated control (black); Concurrent pepinemab treatment significantly inhibited effects of aSyn (green closed squares); Delayed pepinemab treatment significantly reversed effects of aSyn (green open squares)