QIAGEN Reports Second Quarter 2008 Results and Increases Full Year 2008 Adjusted EPS Guidance




 * 61% Revenue Growth, 11% Organic Growth
 * 68% Adjusted Operating Income Growth
 * $0.20 Adjusted EPS

VENLO, The Netherlands, Aug. 4, 2008 (PRIME NEWSWIRE) -- QIAGEN N.V. (Nasdaq:QGEN) (Frankfurt, Prime Standard:QIA) today announced the results of operations for the second quarter and the six-month period ended June 30, 2008.

The reported net sales for the second quarter 2008 were in line with and adjusted earnings per share exceeded the guidance provided by the Company on May 6, 2008.

QIAGEN's second quarter 2008 results include the results of operations of Digene Corporation and eGene, Inc. as well as certain charges related to these acquisitions which occurred after the second quarter of 2007.

Second Quarter and First Six-Month Period 2008 Results

The Company reported that consolidated net sales for its second quarter 2008 increased 61% to $217.9 million from $135.0 million for the same quarter in 2007. Reported operating income for the quarter increased 10% to $34.0 million from $31.0 million in the second quarter of 2007, and net income for the second quarter 2008 increased slightly to $23.2 million from $22.6 million in the same quarter of 2007. Diluted earnings per share for the second quarter decreased to $0.11 in 2008 (based on 205.5 million weighted average shares and share equivalents outstanding) from $0.14 in 2007 (based on 156.9 million weighted average shares and share equivalents outstanding).

On an adjusted basis, second quarter operating income increased 68% to $60.6 million in 2008 from $36.0 million in 2007, and second quarter adjusted net income increased 57% to $40.4 million in 2008 from $25.8 million in 2007. Adjusted diluted earnings per share increased to $0.20 in the second quarter 2008 from $0.16 in 2007.



 ---------------------------------------------------------------------
 QIAGEN's Second Quarter 2008
 (in US$ millions, except per share information)
 ---------------------------------------------------------------------
                                    Q2 2008     Q2 2007     Growth
 ---------------------------------------------------------------------
 Net sales                           217.9       135.0        61%
 Operating income, adj.               60.6        36.0        68%
 Net income, adj.                     40.4        25.8        57%
 EPS, adj. (US$)                      0.20        0.16        25%
 ---------------------------------------------------------------------
 Adjusted figures excluding acquisition, integration and restructuring
 related charges as well as amortization of acquired IP and equity-
 based compensation (SFAS 123R) as detailed in the table below.

For the six-month period ended June 30, 2008, net sales increased 62% to $425.0 million compared to $262.9 million in the comparable period of 2007. Operating income as reported for the first half of 2008 increased 12% to $67.0 million from $59.8 million for the same period in 2007, net income increased 3% to $43.6 million from $42.5 million in 2007, and diluted earnings per share decreased to $0.21 in 2008 from $0.27 in 2007.

On an adjusted basis, operating income for the six-month period ended June 30, 2008 increased 73% to $119.2 million in 2008 from $68.8 million in 2007, and adjusted net income increased 60% to $77.3 million from $48.4 million. Adjusted diluted earnings per share in the six months ended June 30, 2008 increased 23% to $0.38 per share from $0.31 per share in the same period of 2007.

QIAGEN has regularly reported adjusted results to give additional insight into its financial performance. Adjusted results should be considered in addition to the reported results prepared in accordance with generally accepted accounting principles, but should not be considered a substitute. The Company believes certain items should be excluded from adjusted results when they are either outside of our ongoing core operations or vary significantly from period to period, which affects the comparability of results with the Company's competitors and its own prior periods. Costs and charges excluded from adjusted results include acquisition, integration, and restructuring-related costs, acquisition-related amortization, and equity based compensation in accordance with Statement of Financial Accounting Standards No. 123 (Revised) (SFAS 123R).



 ---------------------------------------------------------------------
 QIAGEN's Adjustments to Gross Profit, Operating Income,
  Net Income and EPS
 ---------------------------------------------------------------------
  in US$ millions
  unless indicated       Q2 2008      Q2 2007      6M 2008     6M 2007
 ---------------------------------------------------------------------
 Gross profit
  reported                148.1         91.5        289.3        178.6
 Amortization of
  acquired IP              11.9          2.0         22.8          3.9
 SFAS 123R impact           0.3           --          0.5           --
 Gross profit, adjusted   160.3         93.5        312.6        182.5

 Operating income,
  reported                 34.0         31.0         67.0         59.8
 Acquisition and
  integration related
  charges                   9.3          1.3         18.1          2.0
 Relocation and re-
  structuring charges       0.1          0.1          0.5          0.5
 Amortization of
  acquired IP
  (incl. COS)              14.8          2.7         29.2          5.3
 SFAS 123R impact
  (incl. COS)               2.4          0.9          4.4          1.2
 Operating income,
  adjusted                 60.6         36.0        119.2         68.8

 Net income, reported      23.2         22.6         43.6         42.5
 Acquisition and
  integration related
  charges                   6.1          0.9         11.7          1.3
 Relocation and re-
  structuring charges        --           --          0.3          0.4
 Amortization of
  acquired IP               9.5          1.7         18.8          3.4
 SFAS 123R impact           1.6          0.6          2.9          0.8
 Net income, adjusted      40.4         25.8         77.3         48.4

 Weighted average
  number of diluted
  common shares     205,475,000  156,902,000  205,300,000  156,550,000
 EPS, reported
  in US$                   0.11         0.14         0.21         0.27
 EPS, adjusted
  in US$                   0.20         0.16         0.38         0.31
 ---------------------------------------------------------------------

"QIAGEN experienced a successful second quarter 2008," said Peer Schatz, QIAGEN's Chief Executive Officer. "We saw strong revenue and net income growth and continue to expand our leadership and strategic position. We launched 19 new products in the area of sample and assay technologies with a focus on gene and protein function analysis and in June also started shipping of our new flagship platform, the QIAsymphony which was launched in January 2008 and already received significant interest from our customers across all segments. In line with our projected timelines, in July we transitioned the few remaining projects related to the Digene integration to the line functions in the organization and concluded the Digene integration project in time and above target in terms of planned cost synergies."

"We further expanded our market and technology leadership in molecular diagnostics by adding two important products to QIAGEN's instrumentation platform through the acquisition of Corbett Life Science in July this year. Both products, the Rotor-Gene real-time PCR cycler and the CAS instrument, a reaction set-up system, can be seamlessly combined with QIAGEN's sample and assay technologies portfolio. In addition, the cycler technology can easily be integrated into the QIAsymphony platform to complete an automated system which covers the whole workflow from sample preparation to result measurement in all key areas of PCR-based assay analysis."

"We are very pleased with our financial performance in this second quarter of 2008. Reported revenues were in line with and adjusted earnings per share exceeded our expectations. We experienced a strong adjusted operating margin increase to 28% in the second quarter 2008 which corresponds to a growth rate of 68% year over year reflecting the achievement of cost synergies following the acquisition of Digene," said Roland Sackers, QIAGEN's Chief Financial Officer.

"Revenue growth for the second quarter was 61% and was fueled by a strong organic growth of 11% and a positive contribution of 41% at constant currencies from acquisitions. Our sample and assay portfolio contributed 64% growth (55% at constant exchange rates). QIAGEN's instrumentation business recorded a growth rate of 39% (30% at constant exchange rates) based on the new instruments (QIAsymphonySP and QIAxcel) which started shipping during the second quarter. Net sales in the Americas for the second quarter 2008 represented 49% of our overall business and recorded a growth rate of 96% (95% at constant currencies) while European sales, which represent 40% of our revenues, showed a growth rate of 38% (22% at constant exchange rates). Net sales in Asia remained strong, showing a growth rate of 35% (24% at constant exchange rates)."

Update on Guidance for Fiscal 2008

Based on the first six months and reflecting the revenue contribution of approximately $14 million and the dilution of approximately $0.02 to adjusted earnings per share related to the acquisition of Corbett Life Science, QIAGEN updated its guidance for the full year 2008. QIAGEN adjusted its revenue guidance for fiscal 2008 to $889-$919 million and increased its guidance for adjusted earnings per share from adjusted $0.74-$0.78 to $0.79-$0.80.



 ---------------------------------------------------------------------
 QIAGEN's Second Quarter 2008 at Constant Currencies
 ---------------------------------------------------------------------
                             2008
                              Q2                        Growth Rate
 As percentage        ------------------    2007    ------------------
  of net sales,                 Constant     Q2               Constant
  unless indicated    Reported  Currency  Reported  Reported  Currency
 ---------------------------------------  --------  ------------------
 Consumables             90%      91%       89%        64%       55%
 Instruments              9%       9%       10%        39%       30%
 Others                   1%       0%        1%        41%       26%
 ---------------------------------------------------------------------
 Total revenues         100%     100%      100%        61%       52%
 ---------------------------------------------------------------------

 Gross margin            68%      68%       68%        62%       53%
 Gross margin, adj       74%      74%       69%        72%       63%

 Operating income
  margin                 16%      16%       23%        10%        8%
 Operating income
  margin, adj            28%      29%       27%        68%       66%

 Net income margin       11%      11%       17%         3%        2%
 Net income margin, adj  19%      19%       19%        57%       55%

 EPS in US$
  per share             0.11     0.11      0.14       -21%      -21%
 EPS in US$ per
  share, adj            0.20     0.19      0.16        25%       19%
 ---------------------------------------------------------------------
 Adjusted figures excluding acquisition, integration and restructuring
 related charges as well as amortization of acquired IP and equity-
 based compensation (SFAS 123R) - as detailed in the table above.

Detailed information on QIAGEN's business and financial performance will be presented in its conference call on August 5, 2008 at 9:30am ET. The corresponding presentation slides will be available for download on QIAGEN's website at www.qiagen.com/goto/050808. A webcast of the conference call will be available on the same website at www.qiagen.com/goto/050808.

QIAGEN - Sample and Assay Technologies Highlights:



 * QIAGEN acquired Corbett Life Science Pty. Ltd., a privately held
   developer, manufacturer, and distributor of life sciences
   instrumentation headquartered in Sydney, Australia on July 1. Corbett
   is best known for the world's first rotary real-time PCR cycler system
   -- the Rotor-Gene(tm) -- a system used to detect and measure real-time
   polymerase chain reaction (PCR) reactions. The addition of this
   proprietary PCR detection technology extends QIAGEN's molecular testing
   solution portfolio and enhances QIAGEN's options to offer sample and
   assay technology solutions spanning from sample to result. The Corbett
   Rotor-Gene real-time PCR cycler is an excellent complement to QIAGEN's
   portfolio of current and future molecular testing solutions, including
   its modular processing platform QIAsymphony. Shortly prior to the
   acquisition of Corbett by QIAGEN, Corbett acquired a license for
   certain Idaho Technologies patents related to real-time PCR
   instrumentation and applications.

 * QIAGEN launched 19 new products in the area of sample & assay
   technologies including a series of innovative products for micro RNA
   (miRNA) and epigenetic processing and analysis. In addition, QIAGEN
   launched a number of assay technologies including two CE-marked tests
   (HIV-1 and borrelia) as well as tests for the applied testing markets
   (bovine virus diarrhea virus (BVD) in cattle and Taylorella
   equigenitalis in horses).

 * The German Association of Gynaecology and Obstetrics (Deutsche
   Gesellschaft fur Gynakologie und Geburtshilfe, DGGG) announced 
   clinical guidelines "S-2-guidelines for the prevention, diagnostic and
   therapy of HPV infections and pre-invasive lesions of female genitals"
   and recommend the implementation of an HPV test in conjunction with 
   the Pap Smear test for routine screening of women age 30 and above in
   Germany. The reimbursement and the implementation of the HPV test with
   routine screening "will help to identify pre-stages of cervical cancer
   that are treatable and at the same time will avoid more significant
   surgeries with patients when presenting late-stage symptoms of cervical
   cancer."

About QIAGEN:

QIAGEN N.V., a Netherlands holding company, is the leading global provider of sample and assay technologies. Sample technologies are used to isolate and process DNA, RNA and proteins from biological samples such as blood or tissue. Assay technologies are used to make such isolated biomolecules visible. QIAGEN has developed and markets more than 500 sample and assay products as well as automated solutions for such consumables. The company provides its products to molecular diagnostics laboratories, academic researchers, pharmaceutical and biotechnology companies, and applied testing customers for purposes such as forensics, animal or food testing and pharmaceutical process control. QIAGEN's assay technologies include one of the broadest panels of molecular diagnostic tests available worldwide. This panel includes the only FDA-approved test for human papillomavirus (HPV), the primary cause of cervical cancer. QIAGEN employs more than 2,800 people in over 30 locations worldwide. Further information about QIAGEN can be found at www.qiagen.com.

The QIAGEN N.V. logo is available at http://www.primenewswire.com/newsroom/prs/?pkgid=3692

Certain of the statements contained in this news release may be considered forward-looking statements within the meaning of Section 27A of the U.S. Securities Act of 1933, as amended, and Section 21E of the U.S. Securities Exchange Act of 1934, as amended. To the extent that any of the statements contained herein relating to QIAGEN's products, markets, strategy or operating results are forward-looking, such statements are based on current expectations that involve a number of uncertainties and risks. Such uncertainties and risks include, but are not limited to, risks associated with management of growth and international operations (including the effects of currency fluctuations and risks of dependency on logistics), variability of operating results, the commercial development of the applied testing markets, clinical research markets and proteomics markets, women's health/HPV testing markets, nucleic acid-based molecular diagnostics market, and genetic vaccination and gene therapy markets, changing relationships with customers, suppliers and strategic partners, competition, rapid or unexpected changes in technologies, fluctuations in demand for QIAGEN's products (including fluctuations due to the level and timing of customers' funding, budgets, and other factors), our ability to obtain regulatory approval of our infectious disease panels, difficulties in successfully adapting QIAGEN's products to integrated solutions and producing such products, the ability of QIAGEN to identify and develop new products and to differentiate its products from competitors' products, market acceptance of QIAGEN's new products and the integration of acquired technologies and businesses. For further information, refer to the discussions in reports that QIAGEN has filed with, or furnished to, the U.S. Securities and Exchange Commission (SEC).



                              QIAGEN N.V.
              CONDENSED CONSOLIDATED STATEMENTS OF INCOME
                              (unaudited)

                                                  Three months ended
 (in US$ thousands, except per share data)              June 30,
                                                  --------------------
                                                    2008        2007
                                                  --------    --------
 Net sales                                        $217,888    $135,039
 Cost of sales                                      57,863      41,577
 Cost of sales - acquisition related
  intangible amortization                           11,949       1,943
                                                  --------    --------
     Gross profit                                  148,076      91,519
                                                  --------    --------
 Operating Expenses:
  Research and development                          23,840      12,690
  Sales and marketing                               57,696      31,995
  General and administrative                        20,297      13,666
  Acquisition, integration and related costs         9,342       1,346
  Acquisition related intangible amortization           74          70
  Relocation and restructuring costs                 2,816         715
                                                  --------    --------
 Total operating expenses                          114,065      60,482
                                                  --------    --------
 Income from operations                             34,011      31,037
                                                  --------    --------
 Other Income (Expense):
  Interest income                                    2,324       5,260
  (Interest expense)                                (9,187)     (4,923)
  Other income, net                                    424       1,135
                                                  --------    --------
 Total other income (expense)                       (6,439)      1,472
                                                  --------    --------
  Income before provision for income
   taxes and minority interest                      27,572      32,509
  Provision for income taxes                         4,291       9,926
  Minority interest                                     56          --
                                                  --------    --------
     Net income                                   $ 23,225    $ 22,583
                                                  ========    ========
   Weighted average number of diluted
    common shares                                  205,475     156,902

   Diluted net income per common share            $   0.11    $   0.14

   Diluted net income per common share excluding
    acquisition, integration and restructuring
    related charges as well as amortization of
    acquired IP and equity-based compensation
    (SFAS 123R)                                   $   0.20    $   0.16


                              QIAGEN N.V.
              CONDENSED CONSOLIDATED STATEMENTS OF INCOME
                              (unaudited)
                                                    Six months ended
 (in US$ thousands, except per share data)               June 30,
                                                  --------------------
                                                    2008        2007
                                                  --------    --------
 Net sales                                        $424,994    $262,918
 Cost of sales                                     112,919      80,506
 Cost of sales - acquisition related intangible
  amortization                                      22,775       3,850
                                                  --------    --------
  Gross profit                                     289,300     178,562
                                                  --------    --------
 Operating Expenses:
  Research and development                          45,209      24,221
  Sales and marketing                              111,774      63,298
  General and administrative                        40,201      27,290
  Acquisition, integration and related costs        18,067       2,036
  Acquisition related intangible amortization          534         478
  Relocation and restructuring costs                 6,466       1,406
                                                  --------    --------
 Total operating expenses                          222,251     118,729
                                                  --------    --------

 Income from operations                             67,049      59,833
                                                  --------    --------
 Other Income (Expense):
  Interest income                                    5,296      10,426
  (Interest expense)                               (19,637)     (9,614)
  Other income, net                                  2,559         881
                                                  --------    --------
 Total other income (expense)                      (11,782)      1,693
                                                  --------    --------
  Income before provision for income taxes
   and minority interest                            55,267      61,526
  Provision for income taxes                        11,592      19,076
  Minority interest                                    116          --
                                                  --------    --------
  Net income                                      $ 43,559    $ 42,450
                                                  ========    ========
  Weighted average number of diluted
   common shares                                   205,300     156,550

  Diluted net income per common share             $   0.21    $   0.27

 Diluted net income per common share
  excluding acquisition, integration
  and restructuring related charges as
  well as  amortization of acquired IP and
  equity-based compensation (SFAS 123R)           $   0.38    $   0.31


                              QIAGEN N.V.
                 CONDENSED CONSOLIDATED BALANCE SHEETS

                                                June 30,   December 31,
                                                  2008         2007
 (in thousands US$)                           (unaudited)
                                               ----------   ----------
 Assets

 Current Assets:
   Cash and cash equivalents                   $  380,667   $  347,320
   Marketable securities                               --        2,313
   Notes receivable                                 3,482        5,139
   Accounts receivable, net                       148,675      136,707
   Income taxes receivable                         17,805       10,696
   Inventories                                    107,768       88,346
   Deferred income taxes                           38,697       23,732
   Prepaid expenses and other                      38,277       33,693
                                               ----------   ----------
     Total current assets                         735,371      647,946
                                               ----------   ----------
 Long-Term Assets:
   Property, plant and equipment, net             301,040      283,491
   Goodwill                                     1,116,518    1,107,882
   Intangible assets, net                         618,908      639,107
   Deferred income taxes                           69,836       72,128
   Other assets                                    31,859       24,620
                                               ----------   ----------
      Total long-term assets                    2,138,161    2,127,228
                                               ----------   ----------
      Total assets                             $2,873,532   $2,775,174
                                               ==========   ==========
 Liabilities and Shareholders' Equity

 Current Liabilities:
   Short term loans                            $       --   $        4
   Current portion of capital lease obligations     2,956        2,769
   Accounts payable                                39,354       40,379
   Accrued and other liabilities                  108,689      104,220
   Income taxes payable                            25,290       13,456
   Deferred income taxes                            6,628        4,903
                                               ----------   ----------
     Total current liabilities                    182,917      165,731
                                               ----------   ----------
 Long-Term Liabilities:
   Long-term debt, net of current portion         950,000      950,000
   Capital lease obligations, net of
    current portion                                32,441       33,017
   Deferred income taxes                          217,909      225,893
   Other                                           10,567        8,405
                                               ----------   ----------
     Total long-term liabilities                1,210,917    1,217,315
                                               ----------   ----------
 Minority interest in consolidated
  subsidiaries                                        669          553
                                               ----------   ----------
 Shareholders' Equity:
  Common shares, EUR .01 par value:
    Authorized--410,000,000 shares
     Issued and outstanding--196,519,000 shares
     in 2008 and 195,335,000 shares in 2007         2,193        2,175
    Additional paid-in-capital                    942,701      925,597
    Retained earnings                             432,338      388,779
    Accumulated other comprehensive income        101,797       75,024
                                               ----------   ----------
     Total shareholders' equity                 1,479,029    1,391,575
                                               ----------   ----------
     Total liabilities and
      shareholders' equity                     $2,873,532   $2,775,174
                                               ==========   ==========


            

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