REPURCHASE OF SHARES IN ASTRAZENECA PLC

REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 9 August to 10 December 2010,
AstraZeneca PLC announced that under the terms of that programme it
purchased for cancellation 144,957 ordinary shares of AstraZeneca PLC at
a price of 3091 pence per share on 9 November 2010. Upon the
cancellation of these shares, the number of shares in issue will be
1,419,552,239.
 

A C N Kemp
Company Secretary
10 November 2010