Genovis launches GlycINATOR™ for analysis of antibody molecules


Genovis is launching GlycINATOR at the Well Characterized Biologicals conference
in Washington DC on October 21. The product is the result of a collaboration
between Genovis and a research group led by Mattias Collin at Lund University.
GlycINATOR is a recombinant EndoS2* enzyme and the product is marketed as a
single-use reagent to be used in characterization of monoclonal antibodies.
Customers are mainly active in pharmaceutical and biotech companies.
"It has been exciting to watch this development project progress to finished
product. The project involves working closely with Lund University and Genovis’
relationship with innovative scientists is an important competitive advantage
for strategic product development. GlycINATOR is an excellent addition to our
product portfolio and strengthens our offering of glycan analysis products. In
Washington we will also demonstrate a method in which IgGZERO can be used in
combination with GlycINATOR to carry out a relatively simple quantitative
analysis of high-mannose molecules on monoclonal antibodies. Mannose is a
particularly important parameter to understand and handle when developing
production processes for antibody-based drugs,” says Sarah Fredriksson, CEO of
Genovis.

Genovis has developed the product GlycINATOR, which can rapidly cleave
carbohydrate molecules from IgG molecules. GlycINATOR is a recombinant enzyme.
The yield is high, the reaction rate is fast and the enzyme does not affect the
antibody molecule in general, but is very specific. Customers will primarily use
the product for screening new drug substances, developing production processes
and for quality control of new antibody-based drugs.

*EndoS2 is a specific endoglycosidase from the microorganism Streptococcus
pyogenes. EndoS2 is a patented enzyme and Genovis owns all rights. GlycINATOR™
is the brand name of the recombinant EndoS2.
For more information, please contact: Sarah Fredriksson, CEO, Genovis AB Tel: 46
(0)46 -101235 sarah.fredriksson@genovis.com
ABOUT GENOVIS

Genovis’ business concept is to develop, produce and market innovative
technologies that facilitate and enable development of new treatment methods and
diagnostics for customers in the medical device and pharmaceutical industries.
The Group consists of Genovis AB and the subsidiary GeccoDots AB. Genovis
develops and sells unique enzymes (protein engineering portfolio) in innovative
product formats that facilitate development and quality control of and
biological drugs. GeccoDots uses nanotechnology to produce a new type of
contrast agent that is used in medical imaging.

Genovis shares are listed on NASDAQ OMX First North, and Thenberg Fondkommission
is Certified Adviser for the Company, t: 46 (0)31-745 50 00

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