Global $19.4 Bn Gene Expression Markets to 2028 - Rise in Investments for the Development of Alternative Drug Discovery Approaches

Dublin, Sept. 20, 2021 (GLOBE NEWSWIRE) -- The "Global Gene Expression Markets, 2021-2028" report has been added to's offering.

The global gene expression market size is anticipated to reach USD 19.4 billion by 2028 registering a CAGR of 9.96% from 2021 to 2028.

Rise in investments for the development of alternative drug discovery approaches coupled with an increase in research activities for genetic studies is expected to drive the global market.

A rise in awareness about the potential application of genetic studies has led to an increase in investments for the development and launch of novel products. For instance, in August 2020, Lexogen GmbH launched the QuantSeq-Pool Sample-Barcoded 3' mRNA-Seq Library Prep Kit to expedite multiplexing capacities during gene expression profiling. The company's new QuantSeq-Pool kit also facilitates the sequencing of up to 36,864 RNA samples in parallel, thereby reducing cost and time.

Furthermore, the decrease in cost associated with sequencing posed as a major driver in the last few years. According to the National Human Genome Research Institute (NHGRI), the cost of sequencing per genome reduced from USD 46.77 thousand in 2010 to USD 0.689 thousand in 2020.

This dramatic 98.5% decline in sequencing costs within a decade has increased research involving genomic expression profiling studies.

Gene Expression Market Report Highlights

  • cDNA synthesis & conversion dominated the process segment in 2020. High demand for personalized medicine coupled with technological advancements in sequencing techniques has enhanced the application of cDNA synthesis to produce genomic libraries
  • Moreover, the introduction of systems that provide direct library synthesis has eliminated the need for prior steps, which increases revenue share
  • Kits and reagents product generated the largest revenue in 2020 due to their high usage during the process
  • In addition, ongoing innovation in the kits and reagents dedicated for specific applications contributes to the highest share of the segment
  • High-Plex capacity is expected to register the fastest CAGR during the forecast period owing to the higher accuracy and increased application in cancer research
  • RNA exp. was the largest revenue-contributing technique in 2020 owing to higher adoption of RNA exp. analysis
  • Moreover, the introduction of high-throughput validation methods, such as targeted RNA sequencing, which are useful in broader screening technologies, has increased the revenue generation in the segment
  • The drug discovery & development segment accounted for the largest revenue share in 2020 as Gene Exp. Signature (GES) is commonly used for the development of novel molecules for multifactorial cellular diseases like cancer, diabetes, tuberculosis, malaria, AIDS, and other infectious diseases
  • North America was the dominant regional market in 2020. This can be attributed to the high adoption of advanced gene exp. technology in the region
  • Major market participants, such as Thermo Fisher Scientific, Inc. and Agilent Technologies, have undertaken strategic initiatives to strengthen their position in the market
  • In March 2020, Thermo Fisher Scientific, Inc. launched the PowerTrack SYBR Green PCR Master Mix for real-time PCR workflow. The product is intended to amplify targets for precise analysis

Key Topics Covered:

Chapter 1 Research Methodology

Chapter 2 Executive Summary

Chapter 3 Gene Expression Market Variables, Trends& Scope
3.1 Market Segmentation & Scope
3.1.1 Market driver analysis Declining price of sequencing Decline in cost of per genome sequencing Decline in cost of per megabase DNA sequencing Technological advances that enhance gene expression analysis results High investment in genomic research Estimates of Research, Condition, and Disease Categories (RCDC) funding for cancer genomics High cancer incidence Increased focus on precision medicine
3.1.2 Market restraint analysis High price of important instruments Challenges in data analysis
3.2 Penetration &Growth Prospect Mapping for Process, 2020
3.3 Gene Expression -Swot Analysis, By Factor (Political & Legal, Economic And Technological)
3.4 Industry Analysis - Porter's

Chapter 4 Gene Expression Market Categorization: Process Estimates & Trend Analysis
4.1 Global Gene Expression Market: Process Movement Analysis, 2020 & 2028
4.2 Sample Collection
4.3 Purification
4.4 cDNA Synthesis & Conversion
4.5 PCR Analysis
4.6 Data Analysis & Interpretation

Chapter 5 Gene Expression Market Categorization: Product Estimates & Trend Analysis
5.1 Global Gene Expression Market: Product Movement Analysis, 2020 & 2028
5.2 Kits & Reagents
5.3 DNA Chip/Microarray

Chapter 6 Gene Expression Market Categorization: Capacity Estimates & Trend Analysis
6.1 Global Gene Expression Market: Capacity Movement Analysis, 2020 & 2028
6.2 Low- to Mid-Plex
6.3 High-Plex

Chapter 7 Gene Expression Market Categorization: Technique Estimates & Trend Analysis
7.1 Global Gene Expression Market: Technique Movement Analysis, 2020 & 2028
7.2 RNA Expression
7.2.1 Global RNA expression market, 2017 - 2028 (USD Million)
7.2.2 Northern blotting
7.2.3 DNA microarrays
7.2.4 PCR
7.2.5 RNA-Seq
7.3 Promoter Analysis
7.3.1 Global promoter analysis market, 2017 - 2028 (USD Million)
7.3.2 In vitro transcription/nuclear run-on assays
7.3.3 Gel shift assays
7.3.4 Chromatin immunoprecipitation (ChIP) assays
7.4 Protein Expression & Post-translational Modification Analysis
7.4.1 Global protein expression & post-translational modification analysis market, 2017 - 2028 (USD Million)
7.4.2 Western blotting
7.4.3 2-D Gel Electrophoresis
7.4.4 Immunoassays
7.4.5 Mass spectrometry

Chapter 8 Gene Expression Market Categorization: Application Estimates & Trend Analysis
8.1 Global Gene Expression Market: Application Movement Analysis, 2020 & 2028
8.2 Drug Discovery & Development (DD&D)
8.2.1 Global drug discovery & development market, 2017 - 2028 (USD Million)
8.3 Clinical Diagnostics
8.3.1 Global clinical diagnostics market, 2017 - 2028 (USD Million)
8.3.2 Clinical diagnostics using RNA expression
8.3.3 Clinical diagnostics using other techniques
8.4 Biotechnology & Microbiology
8.5 Others (Forensic, Environmental, Agriculture, Bioenergy)

Chapter 9 Gene Expression Market Categorization: Regional Estimates & Trend Analysis, by Process, Product, Capacity, Technique & Application
9.1 Gene Expression Market Share by Region, 2020 & 2028

Chapter 10 Competitive Landscape
10.1 Market Players List
10.2 Strategy Framework
10.3 Market Participation Categorization
10.4Company Profiles

  • Quest Diagnostics Incorporated
  • F. Hoffmann-La Roche Ltd
  • Illumina, Inc.
  • Novogene Corporation
  • PerkinElmer, Inc.
  • Bio-Rad Laboratories, Inc.
  • Thermo Fisher Scientific, Inc.
  • Agilent Technologies
  • GE Healthcare Dharmacon, Inc.
  • Promega Corporation
  • Luminex Corporation
  • Oxford Gene Technology
  • Danaher
  • ELITech Group
  • Myriad Genetics
  • AutoGenomics
  • Biocartis
  • IntegraGen.
  • Interpace Diagnostics, LLC.
  • Fluidigm Corporation

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