Oligonucleotide Synthesis Market to Register CAGR of 9.5% from 2019 to 2027, TMR Report

Pioneering role of pharmaceutical and biotechnology companies to synthesize oligonucleotides of extreme lengths is key toward oligonucleotide synthesis market expansion


Wilmington, Delaware, United States, June 29, 2022 (GLOBE NEWSWIRE) -- Extensive applications of oligonucleotides in biotechnology, molecular biology, and research studies to lead to handsome revenue of oligonucleotide synthesis market at the end of the forecast period. Expanding use of oligonucleotides in clinical and diagnostics spaces to boost prospects of oligonucleotide synthesis market.

Need to substitute natural oligonucleotides that are extensively used for the selection and determination of DNA sequences, gene construction, and site-directed mutagenesis has led to crucial technological advancements in synthetic chemistry. Selective inhibiting of gene expression for in vitro studies for diagnostics, ability to interact with proteins to create opportunity for therapeutics, and research studies are some key functional areas of natural oligonucleotides that need to be substituted with synthetic ones.

Advanced processes for synthesis of oligonucleotides provides longer oligos with improved sequence strength and higher purity that can be used in a number of molecular biology applications. This provides impetus to oligonucleotide synthesis market.

Consistent efforts of various pharmaceutical and biotechnology companies toward developing newer and advanced methods in synthetic chemistry to open largest opportunity in the oligonucleotide synthesis market. For instance, Integrated DNA Technologies pioneered methods to synthesize oligonucleotides with base lengths up to 200 used with mass spectrometry for the manufacture of mini-genes.

Vast applications in research as well as in diagnostics and therapeutics substantiates immense market demand for oligonucleotide synthesis. Synthesized oligonucleotides are also available as customized oligos that are prepared as per need. Broadly, the two commercially available synthesized oligonucleotides are: DNA oligonucleotides and RNA oligonucleotides.

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Oligonucleotide Synthesis Market – Key Findings of the Report

  • Synthesized oligonucleotides product type led among other key market segments of oligonucleotide synthesis in 2018 and is anticipated to continue to stay ahead during the forecast period
  • Research application segment held the leading share of oligonucleotide synthesis market in 2018. Factors such as focus on R&D along with advances in techniques such as polymerase chain reaction and next generation sequencing fuel growth of research segment. Nonetheless, therapeutics application segment is anticipated to emerge significant on the back of rising applications in therapeutics and growing R&D in RNAi therapeutic drugs.
  • North America accounted for major share of oligonucleotide synthesis market in 2018. Substantial number of ongoing or recently completed clinical trials in the oligonucleotide segment in the U.S. create opportunities in oligonucleotide synthesis market of the region.
  • Asia Pacific is anticipated to emerge as a key region in the oligonucleotide synthesis market during the forecast period. Factors such as growing focus on personalized medicine and expanding biotechnology and life science research activities in China, India, and Japan are fueling the growth of oligonucleotide synthesis market of the region.

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Oligonucleotide Synthesis Market – Growth Drivers

  • Slew of technological advancements in synthetic chemistry such as advances in development of organic molecules and advanced synthesis of oligonucleotides propels the oligonucleotide synthesis market
  • Key role of pharmaceutical and biotechnology companies to work on newer and advanced methods in synthetic chemistry underscores growth in oligonucleotide synthesis market

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Oligonucleotide Synthesis Market – Key Players

Some of the key players operating in the oligonucleotide synthesis market are;

  • GE Healthcare
  • Agilent Technologies Inc.
  • Integrated DNA Technologies Inc.
  • BioAutomation
  • Eurofins Genomics
  • Thermo Fisher Scientific
  • Merck KGaA
  • Kaneka Eurogentec S.A
  • Gene Design Inc.
  • ATDBio Ltd

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The oligonucleotide synthesis market is segmented as follows;

Oligonucleotide Synthesis Market, by Product Type

  • Reagents & Consumables
  • Equipment
  • Synthesized Oligos

    • DNA Oligonucleotides
    • RNA Oligonucleotides
    • Others

Oligonucleotide Synthesis Market, by Application

  • Research
    • Polymerase Chain Reaction
    • Next Generation Sequencing
    • Others
  • Therapeutics
    • Antisense Oligonucleotides
    • Nucleic Acid Aptamers

  • Diagnostic

Oligonucleotide Synthesis Market, by End User

  • Biotech & Pharma Companies
  • Research Inst.
  • Diagnostic Labs

Oligonucleotide Synthesis Market, by Region

  • North America
    • U.S.
    • Canada

  • Europe

    • Germany
    • U.K.
    • France
    • Italy
    • Spain
    • Rest of Europe

  • Asia pacific

    • China
    • India
    • Japan
    • Australia & New Zealand
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC Countries
    • South Africa
    • Rest of Middle East & Africa

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