Global Human Liver Model Market 2025-2030: Growth Driven by 3D Bioprinting & Liver Disease Research

The global human liver model market, valued at $1.34 billion in 2024, is projected to grow at a CAGR of 14.04% through 2030, reaching $2.92 billion. This surge is fueled by the rising prevalence of liver diseases, advancements in 3D organ printing, and increasing demand for liver cancer therapeutics. Human liver models are revolutionizing drug development, toxicology testing, and disease research by providing more accurate and personalized study platforms. This report delivers insights into key industry trends, market segmentation, and leading companies like Merck, Organovo Holdings, and BioIVT, making it essential for stakeholders navigating this evolving market.


Dublin, Feb. 27, 2025 (GLOBE NEWSWIRE) -- The "Human Liver Model Market Size, Share & Trends Analysis Report By Product (2D Models, 3D Models), By Application (ADME Studies, Toxicology Testing), By End Use, By Region, And Segment Forecasts, 2025 - 2030" report has been added to ResearchAndMarkets.com's offering.

The global human liver model market size was valued at USD 1.34 billion in 2024 and is projected to grow at a CAGR of 14.04% from 2025 to 2030. The industry is driven by the increasing prevalence of liver diseases, advancements in organ printing technologies, and increased demand for therapeutic drugs for liver cancer, which is expected to propel its growth.



According to the Health Resources & Services Administration, in 2023, in the U.S., 106,800 individuals are waiting for organ transplants. The healthcare landscape is evolving, and advancements in 3D printing technology are set to transform healthcare by addressing organ shortages and improving patient care globally.

The prevalence of liver diseases is on the rise globally, leading to a growing demand for advanced research tools, including human liver models. Chronic liver conditions such as non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, viral hepatitis, and liver cancer are becoming increasingly common due to factors such as unhealthy diets, sedentary lifestyles, alcohol consumption, and viral infections. For instance, NAFLD emerged as the most prevalent chronic liver disorder in Western countries, affecting approximately 25% of the global population. This significant rise in the prevalence of liver diseases has driven the urgent need for more accurate and efficient human liver models to support research and drug development efforts.

Organ 3D printing technologies have advanced significantly recently, particularly in developing human liver models. These advancements have revolutionized regenerative medicine and drug testing by providing more accurate and personalized models for research purposes. For instance, in February 2023, researchers at the University of California San Diego made significant progress in addressing challenging issues in bio-printing 3D-engineered tissues, achieving high cell density, viability, and precise fabrication resolution.

Global Human Liver Model Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, the analyst has segmented the global human liver model market report on the basis of product, application, end-use, and region.

Key Attributes:

Report AttributeDetails
No. of Pages120
Forecast Period2024 - 2030
Estimated Market Value (USD) in 2024$1.34 Billion
Forecasted Market Value (USD) by 2030$2.92 Billion
Compound Annual Growth Rate14.0%
Regions CoveredGlobal



Key Topics Covered:

Chapter 1. Methodology and Scope

Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segment Snapshot
2.3. Competitive Landscape Snapshot

Chapter 3. Human Liver Model Market Variables, Trends & Scope
3.1. Market Lineage Outlook
3.2. Market Dynamics
3.2.1. Market driver analysis
3.2.1.1. Increasing prevalence of liver diseases
3.2.1.2. Advancements in organ printing technologies
3.2.1.3. Increased demand for therapeutic drugs for liver cancer
3.2.2. Market restraint analysis
3.2.2.1. High costs and complexity associated with maintaining human liver models
3.3. Human Liver Model Market Analysis Tools
3.3.1. Industry Analysis - Porter's
3.3.2. PESTEL Analysis
3.3.3. COVID-19 Impact Analysis

Chapter 4. Human Liver Model Market: Product Estimates & Trend Analysis
4.1. Product Segment Dashboard
4.2. Global Human Liver Model Market Product Movement Analysis, 2024 & 2030 (USD Million)
4.3. Global Human Liver Model Market Size and Trend Analysis, by Product, 2018 to 2030 (USD Million)
4.4. 2D Models
4.4.2. Cell Lines
4.4.3. Primary Cells
4.5. 3D Models
4.5.1. 3D models market estimates and forecasts 2018 to 2030 (USD Million)
4.5.2. Liver on Chip
4.5.3. Organoids
4.5.4. Spheroids
4.5.5. Others

Chapter 5. Human Liver Model Market: Application Estimates & Trend Analysis
5.1. Application Segment Dashboard
5.2. Global Human Liver Model Market Application Movement Analysis, 2024 & 2030 (USD Million)
5.3. Global Human Liver Model Market Size and Trend Analysis, by Application, 2018 to 2030 (USD Million)
5.4. ADME Studies
5.5. Toxicology Testing
5.6. Disease Modelling
5.7. Others

Chapter 6. Human Liver Model Market: End-use Estimates & Trend Analysis
6.1. End-use Segment Dashboard
6.2. Global Human Liver Model Market End-use Movement Analysis, 2024 & 2030 (USD Million)
6.3. Global Human Liver Model Market Size and Trend Analysis, by End-use, 2018 to 2030 (USD Million)
6.4. Academic & Research Institutes
6.5. Pharmaceutical & Bioproduct Companies
6.6. Contract Research Organizations

Chapter 7. Human Liver Model Market: Regional Estimates & Trend Analysis
7.1. Human Liver Model Market: Regional Estimates & Trend Analysis by Product, Application, and End-use
7.2. Regional Market Dashboard
7.3. Regional Market Share Analysis, 2024 & 2030

Chapter 8. Competitive Landscape
8.1. Company/Competition Categorization
8.2. Strategy Mapping
8.3. Company Market Position Analysis, 2024
8.4. Company Profiles

  • ATCC
  • Merck
  • AcceGen
  • ZenBio
  • Organovo Holdings
  • BioIVT
  • InSphero
  • Emulate
  • Mimetas
  • CN Bio Innovations

For more information about this report visit https://www.researchandmarkets.com/r/s7z7p4

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Human Liver Model Market

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