Cheshire, UK -- (MARKET WIRE) -- December 7, 2006 --

                            Protherics PLC

                         Appointment of Auditors

London, UK; Brentwood, TN; 7 December 2006 - Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces the appointment of KPMG Audit PLC as auditors to the Company, replacing PricewaterhouseCoopers LLP ("PwC"). PwC have confirmed that there are no circumstances connected with their replacement which should be brought to the notice of the shareholders or creditors of the Company.

                                   |  Ends  |
For further information please contact:


Nick Staples, Director of Corporate Affairs   +44 (0) 7919  480510
Julie Vickers, Company Secretary              +44 (0)1928 518010

Financial Dynamics - press enquiries

London: Ben Atwell, David Yates               +44 (0) 20 7831 3113
New York: John Capodanno, Jonathan Birt       +1 212 850 5600

Or visit

                      This information is provided by RNS
            The company news service from the London Stock Exchange